Development Level

Tbio 28 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal seminal vesicle morph... 2 | 114
abnormal digit morphology 1 | 10
abnormal duodenum morphology 1 | 4
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal limb position 1 | 3
abnormal lung morphology 1 | 26
abnormal nail morphology 1 | 8
decreased fluid intake 1 | 3
decreased startle reflex 1 | 75
hypoactivity 1 | 132
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 101
male infertility 1 | 123
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

psoriasis 18 | 6,694
Carcinoma 17 | 11,493
lung cancer 17 | 4,740
ovarian cancer 16 | 8,520
Cancer 14 | 2,499
glioblastoma 14 | 5,792
non-small cell lung cancer 11 | 2,890
osteosarcoma 11 | 7,950
lung adenocarcinoma 10 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
malignant mesothelioma 9 | 3,232
medulloblastoma, large-cell 9 | 6,241
Autosomal recessive predisposition 8 | 1,442
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
pancreatic cancer 8 | 2,398
ependymoma 7 | 4,679
interstitial cystitis 7 | 2,312
lung carcinoma 7 | 2,843
Breast cancer 6 | 3,578
breast carcinoma 6 | 1,638
invasive ductal carcinoma 6 | 2,951
tuberculosis 6 | 2,010
Atherosclerosis 5 | 291
Coronary artery disease 5 | 268
Kidney cancer 5 | 2,613
Kidney disease 5 | 430
Rheumatoid arthritis 5 | 1,191
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Cerebrovascular disease 4 | 238
Complement deficiency 4 | 14
Disseminated intravascular coagulation 4 | 38
Liver disease 4 | 237
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
esophageal adenocarcinoma 4 | 737
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Amyloidosis 3 | 67
Chemical and Drug Induced Liver Injury 3 | 195
Dementia 3 | 175
Diarrhea 3 | 253
Duchenne muscular dystrophy 3 | 601
Meningitis 3 | 67
Obesity 3 | 678
Schizophrenia 3 | 1,160
Systemic lupus erythematosus 3 | 194
Vascular disease 3 | 319
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
oligodendroglioma 3 | 2,850
Anemia 2 | 365
Antithrombin III deficiency 2 | 14
Arthritis 2 | 290
Arthritis, Juvenile 2 | 126
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Cardiovascular Diseases 2 | 59
Cardiovascular system disease 2 | 246
Cerebrovascular accident 2 | 63
Colonic Neoplasms 2 | 142
Down syndrome 2 | 499
Heart disease 2 | 306
Hypertension 2 | 396
Immunologic Deficiency Syndromes 2 | 113
Juvenile arthritis 2 | 126
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Melanoma 2 | 711
Neoplasm Invasiveness 2 | 161
Protein C deficiency 2 | 19
Pulmonary embolism 2 | 55
Recurrence 2 | 33
Relapsing fever 2 | 14
Skin cancer 2 | 469
Thrombophilia 2 | 38
Venous Thrombosis 2 | 47
active Crohn's disease 2 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
gastric carcinoma 2 | 807
interstitial lung disease 2 | 298
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468

Tissue

Endocrine System 32 | 18,159
Liver and Pancreas 32 | 16,750
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Male tissues 31 | 17,142
Urinary Tract 31 | 16,678
Skin and soft tissues 30 | 17,230
Blood and immune system 29 | 16,909
Nervous System 29 | 16,725
Respiratory system 29 | 16,393
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 8 | 4,145

GO Function

endopeptidase inhibitor activi... 33 | 33
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Opiorphin prepropeptide OPRPN Tdark Non-IDG -1.76019 58.0 15
ProSAAS PCSK1N Tbio Non-IDG -2.28833 188.0 73
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
N-acylglucosamine 2-epimerase RENBP Tbio Enzyme -1.54336 33.7 87
Inter-alpha-trypsin inhibitor heavy chain H3 ITIH3 Tbio Non-IDG -1.14795 14.5 38
Putative protein C3P1 C3P1 Tdark Non-IDG 0.00000 0
Pregnancy zone protein PZP Tbio Non-IDG -2.14493 148.1 88
Complement C4-B C4B Tbio Non-IDG -2.99381 1011.9 185
Complement C4-A C4B Tbio Non-IDG -3.04538 1109.8 297
Apolipoprotein(a) LPA Tbio Enzyme -3.51111 3598.6 227