Development Level

Tbio 31 | 11,445
Tdark 8 | 6,588
Tchem 4 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal coat-hair pigmentatio... 2 | 64
abnormal skin morphology 2 | 50
decreased circulating insulin ... 2 | 76
increased startle reflex 2 | 112
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal autopod morphology 1 | 1
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal maxilla morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal nail morphology 1 | 8
abnormal response to novel obj... 1 | 1
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
abnormal tail length 1 | 3
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal vertebrae morphology 1 | 18
brachydactyly 1 | 19
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
hydrometra 1 | 53
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8
vertebral fusion 1 | 23

Disease

osteosarcoma 25 | 7,950
ovarian cancer 22 | 8,520
Carcinoma 19 | 11,493
psoriasis 18 | 6,694
medulloblastoma, large-cell 15 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
group 3 medulloblastoma 13 | 4,104
lung cancer 12 | 4,740
glioblastoma 11 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
atypical teratoid / rhabdoid tumor 10 | 5,112
oligodendroglioma 10 | 2,850
Cancer 9 | 2,499
astrocytic glioma 9 | 2,597
ependymoma 9 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
malignant mesothelioma 9 | 3,232
Breast cancer 8 | 3,578
invasive ductal carcinoma 8 | 2,951
Waldenstrons macroglobulinemia 7 | 765
tuberculosis 7 | 2,010
Astrocytoma, Pilocytic 6 | 3,081
Autosomal recessive predisposition 6 | 1,442
Kidney cancer 6 | 2,613
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Atopic dermatitis 5 | 952
Multiple myeloma 5 | 1,332
adult high grade glioma 5 | 3,801
breast carcinoma 5 | 1,638
non primary Sjogren syndrome sicca 5 | 891
ulcerative colitis 5 | 1,819
Muscle hypotonia 4 | 571
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
pancreatic carcinoma 4 | 562
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Adenocarcinoma of lung 3 | 142
Cockayne syndrome 3 | 60
Epilepsy 3 | 792
Genetic Predisposition to Disease 3 | 27
Lymphoma 3 | 81
Neurodegenerative disease 3 | 414
Pick disease 3 | 1,894
Xeroderma pigmentosum group G 3 | 16
adrenocortical carcinoma 3 | 1,428
ductal carcinoma in situ 3 | 1,745
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
Allergic hypersensitivity disease 2 | 126
Allergic rhinitis 2 | 94
Anxiety 2 | 136
Anxiety disease 2 | 113
Asthma 2 | 385
Barth syndrome 2 | 23
Broad flat nasal bridge 2 | 236
Cortical gyral simplification 2 | 19
Death in early childhood 2 | 82
Death in infancy 2 | 82
Depressive disorder 2 | 409
Eosinophilic esophagitis 2 | 16
Failure to gain weight 2 | 365
Fatigue 2 | 182
Heart disease 2 | 306
Hypereosinophilic syndrome 2 | 71
Infantile onset 2 | 238
Melanoma 2 | 711
Muscle Hypertonia 2 | 88
Nasal bridge wide 2 | 236
Neoplasm Metastasis 2 | 168
Nerve Degeneration 2 | 121
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Patellofemoral pain syndrome 2 | 10
Pediatric failure to thrive 2 | 365
Peripheral Neuropathy 2 | 134
Rheumatoid arthritis 2 | 1,191
Severe combined immunodeficiency 2 | 51
Skeletal muscle atrophy 2 | 139
Stomach Neoplasms 2 | 300
Xeroderma pigmentosum group D 2 | 33
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
gastric cancer 2 | 459
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
hepatocellular carcinoma 2 | 547
inflammatory breast cancer 2 | 286
medulloblastoma 2 | 720
muscle degeneration 2 | 139
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 6 months 2 | 409

Tissue

Male tissues 43 | 17,142
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Skin and soft tissues 40 | 17,230
Urinary Tract 40 | 16,678
Liver and Pancreas 39 | 16,750
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Cardiovascular System 36 | 15,192

Target Family

Enzyme 31 | 4,145
Non-IDG 10 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634

GO Function

endonuclease activity 43 | 43
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxidasin-like protein PXDNL Tbio Non-IDG -1.10753 14.4 0
NEDD4-binding protein 2 N4BP2 Tbio Non-IDG -0.54327 3.39 19
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
Probable inactive ribonuclease-like protein 12 RNASE12 Tdark Enzyme 0.48 0.14 55
Endonuclease domain-containing 1 protein ENDOD1 Tdark Enzyme -0.50645 2.77 77
Protein pelota homolog PELO Tbio Non-IDG -1.33842 18.2 100
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.05993 1094.2 84