Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal vibrissa morphology 1 | 25
decreased circulating alkaline... 1 | 46

Disease

Carcinoma 3 | 11,493
osteosarcoma 3 | 7,950
Colorectal Neoplasms 2 | 243
Dyschromatosis universalis hereditaria 2 | 6
ductal carcinoma in situ 2 | 1,745
glioblastoma 2 | 5,792
medulloblastoma, large-cell 2 | 6,241
ovarian cancer 2 | 8,520
Acute urate nephropathy 1 | 7
Adult onset 1 | 82
Basal Ganglia Calcification, Idiopathic, 1 1 | 5
Basal Ganglia Diseases 1 | 14
Basal ganglia calcification 1 | 27
Breast cancer 1 | 3,578
Cafe au lait spots, multiple 1 | 17
Calcinosis 1 | 70
Cardiac arrest 1 | 36
Cerebral calcification 1 | 43
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Chronic fatigue syndrome 1 | 25
Clouding of corneal stroma 1 | 50
Coloboma 1 | 51
Coloboma of eyelid 1 | 15
Coloboma of lens 1 | 4
Coloboma of macula 1 | 4
Congenital bile acid synthesis defect 1 | 15
Congenital coloboma of iris 1 | 4
Congenital deafness 1 | 185
Congenital ocular coloboma (disorder) 1 | 40
Corneal Opacity 1 | 53
Deafness 1 | 198
Decreased platelet count 1 | 111
Dementia 1 | 175
Dental caries 1 | 164
Depressive disorder 1 | 409
Diarrhea 1 | 253
Diastrophic dysplasia 1 | 21
Dilated ventricles (finding) 1 | 121
Dysarthria 1 | 192
Dyschromatosis symmetrica hereditaria 1 | 4
Dyschromatosis universalis 1 | 1
Dyskeratosis congenita 1 | 24
Epilepsy 1 | 792
Exhibitionism 1 | 7
Fahr's syndrome (disorder) 1 | 4
Forgetful 1 | 40
Freckles 1 | 33
Gout 1 | 106
Haemorrhage subcutaneous 1 | 10
Hearing Loss, Partial 1 | 185
Hepatomegaly 1 | 285
Hereditary macular coloboma 1 | 5
Hyperkalemia 1 | 17
Hyperpigmented macules 1 | 42
Hyperuricemia 1 | 49
Iron metabolism disease 1 | 20
Kidney cancer 1 | 2,613
Kleptomania 1 | 2
Liver cancer 1 | 604
Malformations of Cortical Development, Group II 1 | 31
Melanoma 1 | 711
Memory Loss 1 | 40
Memory impairment 1 | 40
Microphthalmia 1 | 76
Microphthalmia, Isolated, with Coloboma 1 1 | 8
Mycobacterium avium complex disease 1 | 11
N syndrome 1 | 6
Nephrolithiasis 1 | 56
Nonsyndromic deafness 1 | 142
Parkinsonian Disorders 1 | 56
Pendred Syndrome 1 | 22
Peripheral vascular disease 1 | 87
Photosensitivity of skin 1 | 51
Polycystic ovary syndrome 1 | 360
Progressive disorder 1 | 142
Pseudohyperkalemia, Familial, 2, due to Red Cell Leak 1 | 1
Seizures 1 | 596
Skin cancer 1 | 469
Spotty hypopigmentation 1 | 4
Stereotypic Movement Disorder 1 | 42
Stomatocytosis Result 1 | 6
Tangier disease 1 | 10
Thrombocytopenia 1 | 197
Trichotillomania 1 | 7
Uric acid concentration, serum, quantitative trait locus 4 1 | 1
X-linked sideroblastic anemia with ataxia 1 | 3
adult high grade glioma 1 | 3,801
cystic fibrosis 1 | 1,696
hearing impairment 1 | 199
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lingual-facial-buccal dyskinesia 1 | 13
lung cancer 1 | 4,740
nephrosclerosis 1 | 333
non-small cell lung cancer 1 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
primitive neuroectodermal tumor 1 | 3,035

Tissue

Blood and immune system 5 | 16,909
Endocrine System 5 | 18,159
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Respiratory system 5 | 16,393
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Female tissues 4 | 17,400
Nervous System 4 | 16,725
Skin and soft tissues 4 | 17,230

Target Family

Transporter 3 | 473
Ion Channel 1 | 344
Non-IDG 1 | 12,091

GO Function

efflux transmembrane transport... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.90119 75.2 94
Sodium-dependent phosphate transport protein 4 SLC17A3 Tbio Transporter -1.10877 13.3 46
ATP-binding cassette sub-family B member 6, mitochondrial ABCB6 Tbio Transporter -2.65393 430.3 137
ATP-binding cassette sub-family B member 5 ABCB5 Tbio Transporter -2.21763 136.1 270
Xenotropic and polytropic retrovirus receptor 1 XPR1 Tbio Non-IDG -1.98309 97.3 138