Development Level

Tbio 11 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

abnormal lung morphology 2 | 26
abnormal ileum morphology 1 | 2
abnormal seminal vesicle morph... 1 | 114
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
microphthalmia 1 | 26
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ependymoma 11 | 4,679
Carcinoma 9 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
chronic rhinosinusitis 6 | 512
glioblastoma 5 | 5,792
nasopharyngeal carcinoma 5 | 1,058
ovarian cancer 5 | 8,520
Pick disease 4 | 1,894
Primary ciliary dyskinesia 4 | 76
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Asphyxiating thoracic dystrophy 3 | 44
Breast cancer 3 | 3,578
Ciliary Dyskinesia, Primary, 1 3 | 27
Ciliary Motility Disorders 3 | 38
Jeune thoracic dystrophy 3 | 10
Kartagener Syndrome 3 | 38
Male infertility 3 | 206
Polydactyly 3 | 107
Short Rib-Polydactyly Syndrome 3 | 13
Situs Inversus 3 | 65
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
primitive neuroectodermal tumor 3 | 3,035
Abnormal skeletal development 2 | 60
Abnormality of pelvic girdle bone morphology 2 | 37
Abnormality of the clavicle 2 | 14
Abnormality of the metaphyses 2 | 48
Abnormality of the ribs 2 | 32
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Brachydactyly 2 | 156
Cone-shaped epiphyses 2 | 24
Cryptorchidism 2 | 296
Failure to gain weight 2 | 365
Hypoplastic feet 2 | 66
Micromelia 2 | 58
Narrow thorax 2 | 53
Osteochondrodysplasias 2 | 72
Pediatric failure to thrive 2 | 365
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Short rib-polydactyly syndrome, Verma-Naumoff type 2 | 5
Short thorax 2 | 21
Short-rib thoracic dysplasia 3 with or without polydactyly 2 | 9
Situs ambiguus 2 | 25
Sternal anomalies 2 | 19
Ventricular Septal Defects 2 | 119
colon cancer 2 | 1,478
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of the fingernails 1 | 51
Acute disseminated encephalomyelitis 1 | 7
Ambiguous Genitalia 1 | 24
Atrial Septal Defects 1 | 85
Bronchiectasis 1 | 64
Chronic rhinitis 1 | 7
Ciliopathy 1 | 71
Communicating Hydrocephalus 1 | 8
Complement deficiency 1 | 14
Conductive hearing loss 1 | 123
Congenital hypoplasia of kidney 1 | 32
Corneal abnormalities 1 | 6
Cornela disease 1 | 6
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Ellis-Van Creveld syndrome 1 | 19
Headache 1 | 37
Heart valve disease 1 | 39
Hydrops Fetalis 1 | 21
Hypodontia 1 | 81
Hypoplastic toenails 1 | 22
Immotile cilia 1 | 2
Knee joint valgus deformity 1 | 56
Microdontia (disorder) 1 | 59
Mitral valve prolapse 1 | 14
Nail dysplasia 1 | 52
Peg shaped front tooth 1 | 6
Peg-shaped incisors 1 | 6
Peripheral Neuropathy 1 | 134
Pointed front tooth 1 | 6
Pointed incisor 1 | 6
Short distal phalanges 1 | 50
Short hands 1 | 50
Short limb dwarfism, disproportionate 1 | 22
Short ribs 1 | 30
Sinusitis 1 | 65
Thoracic dysplasia 1 | 3
Weight Gain 1 | 100
Wide nose 1 | 35
facioscapulohumeral dystrophy 1 | 288
non-small cell lung carcinoma 1 | 317

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 1 | 4,145

GO Function

dynein heavy chain binding 14 | 14
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WD repeat-containing protein 60 WDR60 Tbio Non-IDG -0.64761 3.98 23
Dynein intermediate chain 1, axonemal DNAI1 Tbio Non-IDG -1.90654 78.9 160
WD repeat-containing protein 63 WDR63 Tdark Non-IDG -0.80448 6.69 25
E3 ubiquitin-protein ligase TRIM58 TRIM58 Tbio Enzyme -1.22144 16.5 88
Cytoplasmic dynein 1 light intermediate chain 2 DYNC1LI2 Tbio Non-IDG -0.61455 3.87 95
WD repeat-containing protein 78 WDR78 Tdark Non-IDG -0.73300 5.33 15
Axonemal dynein light intermediate polypeptide 1 DNALI1 Tdark Non-IDG -0.42364 2.22 150
Cytoplasmic dynein 1 intermediate chain 2 DYNC1I2 Tbio Non-IDG -2.29634 178.5 104
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Cytoplasmic dynein 1 intermediate chain 1 DYNC1I1 Tbio Non-IDG -0.74893 5.97 92