Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating alanine ... 2 | 47
decreased grip strength 2 | 116
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating potassiu... 1 | 20
decreased startle reflex 1 | 75
enlarged spleen 1 | 41
increased hematocrit 1 | 46
polycystic kidney 1 | 15
short tibia 1 | 97

Disease

Carcinoma 10 | 11,493
ovarian cancer 9 | 8,520
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
Breast cancer 6 | 3,578
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
Alzheimer's disease 5 | 658
glioblastoma 5 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
psoriasis 5 | 6,694
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
Dementia 3 | 175
Depressive disorder 3 | 409
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Neurodegenerative disease 3 | 414
Parkinson's disease 3 | 392
Toxic encephalopathy 3 | 141
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
oligodendroglioma 3 | 2,850
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer Disease 2 | 83
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Bradykinesia 2 | 34
Cancer 2 | 2,499
Cerebral atrophy 2 | 178
Cognition Disorders 2 | 32
Cognitive delay 2 | 608
Cortical white matter abnormalities seen on MRI 2 | 18
Down syndrome 2 | 499
Dull intelligence 2 | 645
Electroencephalogram abnormal 2 | 101
Epilepsy 2 | 792
Gait imbalance 2 | 17
Gliosis 2 | 56
Global developmental delay 2 | 608
Highly variable severity 2 | 157
Hypertensive disease 2 | 292
Isolated cases 2 | 72
Leukoaraiosis 2 | 18
Low intelligence 2 | 645
Mental Depression 2 | 333
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Mood Disorders 2 | 184
Muscular atrophy 2 | 71
Neuronal loss 2 | 25
Personality change 2 | 23
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Tauopathies 2 | 3
Variable expressivity 2 | 157
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Apathy 1 | 16
Aphasia 1 | 26
Apraxia 1 | 26
Apraxias 1 | 27
Carcinogenesis 1 | 8
Cardiovascular Abnormalities 1 | 31
Difficulty running 1 | 7
Diplopia 1 | 8
Irritation - emotion 1 | 68
Juvenile rheumatoid arthritis 1 | 111
Koolen de Vries syndrome 1 | 18
Memory Disorders 1 | 40
Morphological abnormality of the pyramidal tract 1 | 12
Neurodegenerative Diseases 1 | 38
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Ophthalmoparesis 1 | 11
Pain 1 | 103
Pick's disease 1 | 15
Poor speech 1 | 37
Postnatal microcephaly 1 | 24
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Problems speaking 1 | 37
Pyramidal sign 1 | 29
Pyramidal tract disease 1 | 12
Restlessness 1 | 14
Supranuclear gaze palsy 1 | 6

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

dynactin binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Sorting nexin-6 SNX6 Tbio Non-IDG -1.02156 10.9 235
BICD family-like cargo adapter 1 BICDL1 Tdark Non-IDG -0.04139 0.95 14
Protein bicaudal D homolog 1 BICD1 Tbio Non-IDG -1.55047 35.1 49
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955
Spectrin beta chain, non-erythrocytic 5 SPTBN5 Tbio Non-IDG -0.41365 2.99 32
Microtubule-associated protein tau MAPT Tchem Non-IDG -3.88207 7239.3 3951
Protein bicaudal D homolog 2 BICD2 Tbio Non-IDG -1.49685 33.0 117