Development Level

Tbio 46 | 10,625
Tchem 8 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 3 | 633
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
abnormal behavior 1 | 226
abnormal retina morphology 1 | 100
decreased body weight 1 | 174
hyperactivity 1 | 108
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased fasted circulating g... 1 | 68
increased granulocyte number 1 | 8
increased grip strength 1 | 83
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 42 | 8,484
lung cancer 30 | 4,466
glioblastoma 29 | 5,572
medulloblastoma, large-cell 29 | 6,234
osteosarcoma 29 | 7,933
psoriasis 27 | 6,685
juvenile dermatomyositis 21 | 1,189
Breast cancer 20 | 3,094
pancreatic cancer 19 | 2,300
dermatomyositis 18 | 933
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
Cancer 17 | 2,346
pediatric high grade glioma 17 | 2,712
pilocytic astrocytoma 17 | 3,086
Multiple myeloma 16 | 1,327
atypical teratoid / rhabdoid tumor 16 | 4,369
invasive ductal carcinoma 16 | 2,950
lung carcinoma 16 | 2,844
acute quadriplegic myopathy 15 | 1,157
ependymoma 15 | 2,514
non-small cell lung cancer 15 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
lung adenocarcinoma 14 | 2,713
subependymal giant cell astrocytoma 14 | 2,287
Waldenstrons macroglobulinemia 13 | 765
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
primary Sjogren syndrome 13 | 789
ulcerative colitis 13 | 2,087
astrocytic glioma 12 | 2,241
cystic fibrosis 12 | 1,665
group 3 medulloblastoma 12 | 2,254
Influenza 11 | 142
cutaneous lupus erythematosus 11 | 1,056
malignant mesothelioma 11 | 3,162
oligodendroglioma 11 | 2,849
primitive neuroectodermal tumor 11 | 3,031
tuberculosis 10 | 1,557
Carcinoma 9 | 2,147
Pick disease 9 | 1,893
interstitial cystitis 9 | 2,299
systemic lupus erythematosus 9 | 156
Amyotrophic Lateral Sclerosis 8 | 431
Multiple Sclerosis 8 | 498
breast carcinoma 8 | 1,614
diabetes mellitus 8 | 1,663
gastric carcinoma 8 | 832
medulloblastoma 8 | 1,524
pituitary cancer 8 | 1,972
posterior fossa group A ependymoma 8 | 1,511
astrocytoma 7 | 1,493
nasopharyngeal carcinoma 7 | 1,056
pancreatic carcinoma 7 | 567
atypical teratoid/rhabdoid tumor 6 | 1,095
colon cancer 6 | 1,475
group 4 medulloblastoma 6 | 1,875
hepatocellular carcinoma 6 | 532
primary pancreatic ductal adenocarcinoma 6 | 1,271
Atopic dermatitis 5 | 944
Rheumatoid Arthritis 5 | 1,160
acute myeloid leukemia 5 | 780
adult high grade glioma 5 | 2,148
hereditary spastic paraplegia 5 | 313
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
progressive supranuclear palsy 5 | 674
sonic hedgehog group medulloblastoma 5 | 1,482
Down syndrome 4 | 548
Duchenne muscular dystrophy 4 | 602
Endometriosis 4 | 535
HIV Infections 4 | 100
Hepatitis C 4 | 90
Hypersensitivity reaction type II disease 4 | 235
West Nile encephalitis 4 | 8
active Crohn's disease 4 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
non primary Sjogren syndrome sicca 4 | 840
posterior fossa group B ependymoma 4 | 1,530
tuberculosis and treatment for 3 months 4 | 327
tuberculosis and treatment for 6 months 4 | 686
Becker muscular dystrophy 3 | 187
IGA Glomerulonephritis 3 | 454
Mammary Neoplasms 3 | 410
Melanoma 3 | 261
Neurodegenerative disease 3 | 383
Polycystic Ovary Syndrome 3 | 332
Prostatic Neoplasms 3 | 471
adrenocortical carcinoma 3 | 1,427
aldosterone-producing adenoma 3 | 664
chronic lymphosyte leukemia 3 | 232
gastric cancer 3 | 430
sarcoidosis 3 | 358
Arthritis 2 | 248
Contact Dermatitis 2 | 80
Myocardial Ischemia 2 | 169
fibroadenoma 2 | 557
inflammatory breast cancer 2 | 404
mucosa-associated lymphoid tissue lymphoma 2 | 480
non diabetic and post-ischemic heart failure 2 | 200
spina bifida 2 | 1,064

Tissue

Blood and immune system 59 | 17,995
Cardiovascular System 59 | 17,958
Digestive Tract 59 | 18,473
Endocrine System 59 | 18,512
Female tissues 59 | 18,647
Liver and Pancreas 59 | 18,136
Male tissues 59 | 17,969
Nervous System 59 | 18,561
Respiratory system 59 | 17,484
Skin and soft tissues 59 | 18,115
Urinary Tract 59 | 18,444

Target Family

Non-IDG 36 | 11,971
Enzyme 20 | 4,146
Kinase 2 | 634
Transporter 1 | 473

GO Function

double-stranded RNA binding 59 | 59
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin enhancer-binding factor 2 ILF2 Tbio Non-IDG -1.51960 36.4 249
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.41582 254.1 201
Toll-like receptor 7 TLR7 Tclin Non-IDG -2.92878 974.2 670
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.82506 66.9 35
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Toll-like receptor 3 TLR3 Tchem Non-IDG -3.00214 1147.2 751
Protein LSM14 homolog A LSM14A Tbio Non-IDG -1.08621 15.6 103
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.14451 13.1 119
SID1 transmembrane family member 2 SIDT2 Tbio Non-IDG -0.64917 8.13 70