Development Level

Tbio 52 | 11,651
Tchem 5 | 1,388
Tdark 3 | 6,593
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal behavior 1 | 298
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
absent spleen 1 | 3
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
hyperactivity 1 | 148
increased blood uric acid leve... 1 | 5
increased body temperature 1 | 9
increased circulating chloride... 1 | 41
increased fasted circulating g... 1 | 76
increased granulocyte number 1 | 1
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased total body fat amoun... 1 | 134
small kidney 1 | 16
small testis 1 | 58
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 54 | 11,493
ovarian cancer 44 | 8,520
lung cancer 31 | 4,740
medulloblastoma, large-cell 31 | 6,241
osteosarcoma 31 | 7,950
glioblastoma 30 | 5,792
psoriasis 29 | 6,694
ependymoma 24 | 4,679
Breast cancer 23 | 3,578
atypical teratoid / rhabdoid tumor 21 | 5,112
group 3 medulloblastoma 21 | 4,104
juvenile dermatomyositis 21 | 1,187
Kidney cancer 19 | 2,613
pancreatic cancer 19 | 2,398
Astrocytoma, Pilocytic 18 | 3,081
Cancer 18 | 2,499
Multiple myeloma 18 | 1,332
adult high grade glioma 18 | 3,801
dermatomyositis 18 | 966
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
acute quadriplegic myopathy 16 | 1,158
invasive ductal carcinoma 16 | 2,951
lung carcinoma 16 | 2,843
astrocytic glioma 15 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
Waldenstrons macroglobulinemia 14 | 765
subependymal giant cell astrocytoma 14 | 2,287
cystic fibrosis 13 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
malignant mesothelioma 13 | 3,232
primary Sjogren syndrome 13 | 735
Influenza 12 | 142
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
ulcerative colitis 12 | 1,819
cutaneous lupus erythematosus 11 | 1,057
tuberculosis 11 | 2,010
Pick disease 9 | 1,894
Systemic lupus erythematosus 9 | 194
diabetes mellitus 9 | 1,728
interstitial cystitis 9 | 2,312
Amyotrophic lateral sclerosis 8 | 451
Influenza, Human 8 | 51
breast carcinoma 8 | 1,638
group 4 medulloblastoma 8 | 1,855
pituitary cancer 8 | 1,972
Microphthalmia with limb anomalies 7 | 40
Multiple Sclerosis 7 | 540
gastric carcinoma 7 | 807
nasopharyngeal carcinoma 7 | 1,058
pancreatic carcinoma 7 | 562
primary pancreatic ductal adenocarcinoma 7 | 1,109
Hypersensitivity reaction type II disease 6 | 253
Schizophrenia 6 | 1,160
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
hepatocellular carcinoma 6 | 547
Atopic dermatitis 5 | 952
HIV Infections 5 | 102
Liver Cirrhosis, Experimental 5 | 769
Melanoma 5 | 711
Rheumatoid arthritis 5 | 1,191
acute myeloid leukemia 5 | 783
gastric cancer 5 | 459
hereditary spastic paraplegia 5 | 318
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
progressive supranuclear palsy 5 | 676
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Endometriosis 4 | 540
Hepatitis C 4 | 94
Mental Depression 4 | 333
West Nile encephalitis 4 | 9
active Crohn's disease 4 | 922
adrenocortical carcinoma 4 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
non primary Sjogren syndrome sicca 4 | 891
tuberculosis and treatment for 6 months 4 | 409
Alzheimer's disease 3 | 658
Arthritis 3 | 290
Becker muscular dystrophy 3 | 191
Depressive disorder 3 | 409
Liver cancer 3 | 604
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Myocardial Ischemia 3 | 169
Neurodegenerative disease 3 | 414
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
atypical teratoid/rhabdoid tumor 3 | 357
chronic lymphosyte leukemia 3 | 204
medulloblastoma 3 | 720
tuberculosis and treatment for 3 months 3 | 179

Tissue

Endocrine System 62 | 18,159
Skin and soft tissues 62 | 17,230
Blood and immune system 61 | 16,909
Cardiovascular System 61 | 15,192
Digestive Tract 61 | 17,369
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Male tissues 61 | 17,142
Nervous System 61 | 16,725
Respiratory system 61 | 16,393
Urinary Tract 61 | 16,678

Target Family

Non-IDG 37 | 12,091
Enzyme 21 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Function

double-stranded RNA binding 62 | 62
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 346 ZNF346 Tbio Non-IDG -2.28393 188.7 213
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like DUS2 Tbio Enzyme -0.88176 8.73 109
Protein argonaute-2 AGO2 Tbio Non-IDG -2.97243 867.1 202
Protein argonaute-1 AGO1 Tbio Non-IDG -2.22336 158.4 203
Double-stranded RNA-binding protein Staufen homolog 1 STAU1 Tbio Non-IDG -2.24156 174.1 258
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.46439 274.8 239
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.84543 68.4 48
Leucine-rich repeat flightless-interacting protein 1 LRRFIP1 Tbio Non-IDG -1.60708 41.5 237
ELAV-like protein 1 ELAVL1 Tchem Non-IDG -2.76074 585.8 338
Interferon-induced helicase C domain-containing protein 1 IFIH1 Tbio Enzyme -2.67869 455.3 335