Development Level

Tbio 7 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal tibia morphology 1 | 14
corneal opacity 1 | 32
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
increased circulating bilirubi... 1 | 16
increased grip strength 1 | 41
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 6 | 6,241
atypical teratoid / rhabdoid tumor 5 | 5,112
lung cancer 5 | 4,740
ovarian cancer 5 | 8,520
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
psoriasis 4 | 6,694
Adrenoleukodystrophy 3 | 29
Arthritis, Experimental 3 | 39
Astrocytoma, Pilocytic 3 | 3,081
Atopic dermatitis 3 | 952
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
active Crohn's disease 3 | 922
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Cerebrovascular disease 2 | 238
Chronic intestinal vascular insufficiency 2 | 12
Coronary artery disease 2 | 268
Down syndrome 2 | 499
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Adenocarcinoma of lung 1 | 142
Alzheimer's disease 1 | 658
Amphetamine-Related Disorders 1 | 74
Animal Mammary Neoplasms 1 | 136
Anteverted nostril 1 | 191
Carcinoma, Hepatocellular 1 | 228
Chronic obstructive pulmonary disease 1 | 184
Concave bridge of nose 1 | 195
Congenital deafness 1 | 185
Deafness 1 | 198
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Depressive disorder 1 | 409
Disease Models, Animal 1 | 155
Downward slant of palpebral fissure 1 | 158
Hearing Loss, Partial 1 | 185
Hypotrophic malar bone 1 | 129
Kidney Failure 1 | 111
Liver Cirrhosis, Experimental 1 | 769
Liver carcinoma 1 | 240
Malar flattening 1 | 129
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Peroxisomal disease 1 | 22
Pick disease 1 | 1,894
Prostatic Neoplasms 1 | 495
Proteinuria 1 | 144
Psychotic Disorders 1 | 151
Renal Insufficiency 1 | 90
Renal failure in adulthood 1 | 76
Schizoaffective Disorder 1 | 55
Severe mental retardation (I.Q. 20-34) 1 | 99
Tapering fingers (finding) 1 | 25
Thin lips 1 | 49
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
glioblastoma multiforme 1 | 142
hair abnormalities (non-specific) 1 | 30
hearing impairment 1 | 199
hepatocellular carcinoma 1 | 547
hereditary spastic paraplegia 1 | 318
juvenile dermatomyositis 1 | 1,187
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
oligodendroglioma 1 | 2,850
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Nervous System 8 | 16,725
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Respiratory system 7 | 16,393
Cardiovascular System 6 | 15,192

Target Family

Enzyme 7 | 4,145
Transporter 1 | 473

GO Function

decanoate--CoA ligase activity 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Long-chain-fatty-acid--CoA ligase 4 ACSL4 Tbio Enzyme -1.88239 83.9 249
Long-chain-fatty-acid--CoA ligase 1 ACSL1 Tbio Enzyme -2.59850 388.5 222
Long-chain-fatty-acid--CoA ligase 5 ACSL5 Tbio Enzyme -1.98202 97.3 170
Long-chain-fatty-acid--CoA ligase 3 ACSL3 Tbio Enzyme -1.53077 28.8 152
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.86749 73.8 139
Very long-chain acyl-CoA synthetase SLC27A2 Tbio Transporter -1.73251 54.7 121
Long-chain-fatty-acid--CoA ligase ACSBG2 ACSBG2 Tdark Enzyme -0.38371 2.13 98
Long-chain-fatty-acid--CoA ligase ACSBG1 ACSBG1 Tbio Enzyme -2.36014 218.3 88