Development Level

Tbio 4 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating insulin ... 1 | 76
decreased threshold for audito... 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 6 | 11,493
ovarian cancer 5 | 8,520
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
Cancer 3 | 2,499
Mood Disorders 3 | 184
Schizophrenia 3 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
primitive neuroectodermal tumor 3 | 3,035
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Carcinoma, Squamous Cell 2 | 110
Cardiovascular system disease 2 | 246
Chronic obstructive pulmonary disease 2 | 184
Endometriosis 2 | 540
Heart Diseases 2 | 43
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Peripheral T-cell lymphoma 2 | 25
Primary cutaneous T-cell lymphoma 2 | 29
Squamous cell carcinoma 2 | 129
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pancreatic cancer 2 | 2,398
psoriasis 2 | 6,694
Acute kidney injury 1 | 70
Alcoholic Intoxication, Chronic 1 | 289
Alzheimer's disease 1 | 658
Atherosclerosis 1 | 291
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Autoimmune Diseases 1 | 67
Brain infarction 1 | 22
Breast Neoplasms 1 | 445
Cardiomegaly 1 | 116
Colitis 1 | 54
Demyelinating Diseases 1 | 7
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Familial primary pulmonary hypertension 1 | 11
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Fibrosis 1 | 44
Gilles de la Tourette syndrome 1 | 47
Glucose Intolerance 1 | 19
HIV Infections 1 | 102
Heart disease 1 | 306
Heart failure 1 | 162
Hemolytic anemia 1 | 77
Huntington's disease 1 | 76
Hyperglycemia 1 | 137
Hypertrophy 1 | 17
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Kabuki syndrome 1 | 27
Kidney disease 1 | 430
Leukemia 1 | 104
Leukemia, Myeloid 1 | 18
Liver Cirrhosis 1 | 181
Liver disease 1 | 237
Liver neoplasms 1 | 130
Macular degeneration 1 | 65
Mammary Neoplasms 1 | 425
Metabolic syndrome X 1 | 52
Microsatellite Instability 1 | 12
Myeloid Leukemia 1 | 19
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Neurodegenerative Disorders 1 | 79
Non-alcoholic Fatty Liver Disease 1 | 42
Nonorganic psychosis 1 | 84
Paralysed 1 | 42
Paralysis 1 | 9
Parkinson's disease 1 | 392
Pneumonia 1 | 174
Pneumonia, Pneumococcal 1 | 6
Psychotic Disorders 1 | 151
Retinal Diseases 1 | 55
Shared Paranoid Disorder 1 | 5
Skin cancer 1 | 469
Streptococcal pneumonia 1 | 6
Substance-Related Disorders 1 | 115
Systemic scleroderma 1 | 60
Toxic encephalopathy 1 | 141
Type 2 diabetes mellitus 1 | 272
Waldenstrons macroglobulinemia 1 | 765
astrocytoma 1 | 1,146
chronic lymphosyte leukemia 1 | 204
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
tuberculosis 1 | 2,010

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192
Respiratory system 7 | 16,393

Target Family

Enzyme 5 | 4,145
Epigenetic 3 | 242

GO Function

deacetylase activity 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
O-acetyl-ADP-ribose deacetylase 1 OARD1 Tdark Enzyme -0.49886 3.04 35
O-acetyl-ADP-ribose deacetylase MACROD2 MACROD2 Tbio Enzyme -1.21785 14.5 19
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 NDST4 Tbio Enzyme -0.92585 7.84 90
Arylacetamide deacetylase AADAC Tbio Enzyme -1.33418 25.6 116
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201
NAD-dependent protein deacetylase sirtuin-1 SIRT1 Tchem Epigenetic -3.50639 3413.7 733
Histone deacetylase 2 HDAC2 Tclin Epigenetic -2.79651 587.9 712
O-acetyl-ADP-ribose deacetylase MACROD1 MACROD1 Tbio Enzyme -1.33327 23.1 34