Development Level

Tbio 39 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal QT variability 2 | 10
abnormal kidney morphology 2 | 65
decreased body length 2 | 101
hyperactivity 2 | 148
increased heart weight 2 | 62
increased startle reflex 2 | 112
abnormal brain morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
hydroencephaly 1 | 14
improved glucose tolerance 1 | 79
increased body temperature 1 | 9
increased circulating alkaline... 1 | 122
increased exploration in new e... 1 | 8
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
long tibia 1 | 25
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 37 | 11,493
ovarian cancer 33 | 8,520
medulloblastoma, large-cell 27 | 6,241
glioblastoma 25 | 5,792
osteosarcoma 25 | 7,950
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 23 | 4,679
lung cancer 22 | 4,740
adult high grade glioma 19 | 3,801
oligodendroglioma 17 | 2,850
pancreatic cancer 17 | 2,398
Astrocytoma, Pilocytic 16 | 3,081
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
invasive ductal carcinoma 16 | 2,951
primitive neuroectodermal tumor 16 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
malignant mesothelioma 15 | 3,232
Kidney cancer 14 | 2,613
non-small cell lung cancer 14 | 2,890
subependymal giant cell astrocytoma 14 | 2,287
Breast cancer 13 | 3,578
colon cancer 13 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
pituitary cancer 13 | 1,972
acute quadriplegic myopathy 12 | 1,158
astrocytic glioma 12 | 2,597
lung adenocarcinoma 12 | 2,716
lung carcinoma 12 | 2,843
Pick disease 10 | 1,894
group 4 medulloblastoma 9 | 1,855
Autosomal recessive predisposition 8 | 1,442
adrenocortical carcinoma 8 | 1,428
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,312
spina bifida 8 | 1,074
Cancer 7 | 2,499
cutaneous lupus erythematosus 7 | 1,057
tuberculosis 7 | 2,010
Cardiomyopathy 6 | 116
Dilated cardiomyopathy 6 | 56
Multiple myeloma 6 | 1,332
Myopathy 6 | 185
active ulcerative colitis 6 | 764
breast carcinoma 6 | 1,638
Duchenne muscular dystrophy 5 | 601
Familial isolated dilated cardiomyopathy 5 | 41
LEFT VENTRICULAR NONCOMPACTION 10 5 | 40
LEFT VENTRICULAR NONCOMPACTION 8 5 | 40
active Crohn's disease 5 | 922
aldosterone-producing adenoma 5 | 665
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
primary pancreatic ductal adenocarcinoma 5 | 1,109
ulcerative colitis 5 | 1,819
Cardiomyopathy, Dilated 4 | 83
Liver Cirrhosis, Experimental 4 | 769
Schizophrenia 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
pancreatic carcinoma 4 | 562
progressive supranuclear palsy 4 | 676
sonic hedgehog group medulloblastoma 4 | 467
Animal Mammary Neoplasms 3 | 136
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Cognitive delay 3 | 608
Creatine phosphokinase serum increased 3 | 110
Elevated creatine kinase 3 | 110
Global developmental delay 3 | 608
Hypertrophic Cardiomyopathy 3 | 117
Icterus 3 | 82
Intellectual disability 3 | 1,016
Mammary Neoplasms, Animal 3 | 136
Mental and motor retardation 3 | 608
Muscle hypotonia 3 | 571
Muscular dystrophy 3 | 75
Myocardial Ischemia 3 | 169
Myofibrillar Myopathy 3 | 9
Prostate carcinoma in situ 3 | 11
fibroadenoma 3 | 559
gastric cancer 3 | 459
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
non primary Sjogren syndrome sicca 3 | 891
periodontitis 3 | 293
tuberculosis and treatment for 6 months 3 | 409
Alzheimer's disease 2 | 658
Down syndrome 2 | 499
Endometriosis 2 | 540
Orofacial cleft 2 | 54
Polycystic ovary syndrome 2 | 360
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333

Tissue

Female tissues 50 | 17,400
Male tissues 50 | 17,142
Skin and soft tissues 50 | 17,230
Blood and immune system 49 | 16,909
Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Nervous System 49 | 16,725
Urinary Tract 49 | 16,678
Liver and Pancreas 48 | 16,750
Respiratory system 48 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 11 | 4,145
Ion Channel 2 | 344
Kinase 1 | 634
Transporter 1 | 473

GO Function

cytoskeletal protein binding 52 | 52
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
FERM, ARHGEF and pleckstrin domain-containing protein 1 FARP1 Tbio Non-IDG -1.56544 38.3 153
Rab effector Noc2 RPH3AL Tbio Non-IDG -1.26757 23.0 148
Sorbin and SH3 domain-containing protein 1 SORBS1 Tbio Non-IDG -1.57341 40.2 224
Tyrosine-protein phosphatase non-receptor type 3 PTPN3 Tbio Enzyme -1.40961 29.1 162
Abl interactor 1 ABI1 Tbio Non-IDG -1.99953 104.1 264
PDZ and LIM domain protein 3 PDLIM3 Tbio Non-IDG -1.20581 15.4 142