Development Level

Tbio 132 | 11,178
Tchem 25 | 1,885
Tclin 11 | 612
Tdark 3 | 6,569

IMPC Phenotype

enlarged heart 7 | 210
preweaning lethality, complete... 7 | 979
decreased vertical activity 6 | 208
abnormal heart morphology 4 | 162
embryonic lethality prior to t... 3 | 278
increased mean corpuscular vol... 3 | 92
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
limb grasping 2 | 41
abnormal brain morphology 1 | 13
abnormal coat- hair morphology 1 | 19
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal lung morphology 1 | 26
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged lymph nodes 1 | 37
enlarged testis 1 | 6
female infertility 1 | 60
hydroencephaly 1 | 14
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
male infertility 1 | 123
pale yolk sac 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small testis 1 | 58
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

psoriasis 81 | 6,514
Cancer 73 | 2,388
Carcinoma 59 | 11,192
ovarian cancer 48 | 8,297
lung cancer 43 | 4,607
tuberculosis 42 | 1,963
glioblastoma 41 | 5,635
malignant mesothelioma 40 | 3,135
osteosarcoma 39 | 7,766
ulcerative colitis 38 | 1,765
adult high grade glioma 37 | 3,701
interstitial cystitis 36 | 2,237
medulloblastoma, large-cell 35 | 6,086
Asthma 34 | 370
Arthritis 33 | 276
Breast cancer 33 | 3,469
diabetes mellitus 33 | 1,683
lung carcinoma 33 | 2,755
Astrocytoma, Pilocytic 32 | 3,006
Hypersensitivity reaction type II disease 31 | 245
Inflammatory bowel disease 31 | 148
Rheumatoid arthritis 31 | 1,156
atypical teratoid / rhabdoid tumor 31 | 4,971
invasive ductal carcinoma 29 | 2,867
pancreatic cancer 29 | 2,322
Multiple Sclerosis 28 | 527
Schizophrenia 28 | 1,136
ependymoma 28 | 4,559
cystic fibrosis 27 | 1,629
lung adenocarcinoma 27 | 2,627
non-small cell lung cancer 26 | 2,799
Kidney disease 24 | 411
Inflammation 23 | 116
Liver Cirrhosis, Experimental 23 | 733
Anemia 22 | 353
Dermatitis 22 | 154
Lung disease 22 | 135
Pulmonary Fibrosis 21 | 101
Hepatitis C 20 | 90
Atherosclerosis 19 | 276
Atopic dermatitis 19 | 915
Breast Neoplasms 19 | 423
Heart disease 19 | 288
Influenza 19 | 136
Mammary Neoplasms 19 | 403
Pneumonia 19 | 169
ductal carcinoma in situ 19 | 1,686
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,872
pituitary cancer 19 | 1,915
Allergic hypersensitivity disease 18 | 124
Arthritis, Rheumatoid 18 | 169
Coronary artery disease 18 | 253
breast carcinoma 18 | 1,589
colon cancer 18 | 1,428
cutaneous lupus erythematosus 18 | 1,016
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,204
Hypereosinophilic syndrome 17 | 70
Osteoporosis 17 | 348
group 3 medulloblastoma 17 | 4,002
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,902
nasopharyngeal carcinoma 17 | 1,024
Allergic rhinitis 16 | 93
Prostatic Neoplasms 16 | 472
periodontitis 16 | 280
sarcoidosis 16 | 357
Autosomal recessive predisposition 15 | 1,407
Brain Injuries 15 | 63
Chemical and Drug Induced Liver Injury 15 | 188
Depressive disorder 15 | 401
Endometriosis 15 | 521
Fever 15 | 136
Hepatitis B 15 | 105
Major Depressive Disorder 15 | 293
Obesity 15 | 655
Thrombocytopenia 15 | 193
subependymal giant cell astrocytoma 15 | 2,230
Abortion, Spontaneous 14 | 93
Acquired immunodeficiency syndrome 14 | 192
Hypersensitivity 14 | 62
Hypertension 14 | 372
Leukopenia 14 | 72
Liver disease 14 | 227
Malaria 14 | 155
Myocardial Infarction 14 | 142
Neuropathy 14 | 254
Spontaneous abortion 14 | 97
Vascular disease 14 | 294
Vasculitis 14 | 76
oligodendroglioma 14 | 2,768
Crohn's disease 13 | 311
Diarrhea 13 | 245
Leishmaniasis 13 | 46
Liver Cirrhosis 13 | 173
Melanoma 13 | 689
Myocardial Ischemia 13 | 162
Unipolar Depression 13 | 244
astrocytic glioma 13 | 2,530
Mental Depression 12 | 325
hepatocellular carcinoma 12 | 536
primary pancreatic ductal adenocarcinoma 12 | 1,071

Tissue

Blood and immune system 148 | 16,909
Endocrine System 147 | 18,159
Digestive Tract 146 | 17,369
Skin and soft tissues 143 | 17,230
Urinary Tract 142 | 16,678
Female tissues 141 | 17,400
Liver and Pancreas 140 | 16,750
Male tissues 137 | 17,142
Respiratory system 128 | 16,393
Nervous System 123 | 16,725
Cardiovascular System 107 | 15,192

Target Family

Non-IDG 164 | 12,091
Enzyme 6 | 4,145
Transcription Factor 1 | 1,400

GO Function

cytokine activity 171 | 171
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Interleukin-17C IL17C Tbio Non-IDG -2.09462 124.6 192
Cardiotrophin-1 CTF1 Tbio Non-IDG -2.30700 246.7 333
Secreted Ly-6/uPAR-related protein 1 SLURP1 Tbio Non-IDG -2.06733 125.7 92
Interleukin-3 IL3 Tbio Non-IDG -3.35359 2101.5 583
Interleukin-5 IL5 Tclin Non-IDG -3.45852 2701.9 571
Glucose-6-phosphate isomerase GPI Tbio Enzyme -2.87105 706.1 447
Gremlin-1 GREM1 Tbio Non-IDG -2.91296 826.9 397
Cardiotrophin-like cytokine factor 1 CLCF1 Tbio Non-IDG -1.35883 23.2 162
CD40 ligand CD40LG Tchem Non-IDG -4.58203 37578.3 1461