Development Level

Tbio 16 | 11,178
Tchem 14 | 1,885
Tdark 2 | 6,569

IMPC Phenotype

decreased blood urea nitrogen ... 2 | 51
decreased prepulse inhibition 2 | 82
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 17 | 11,192
ovarian cancer 14 | 8,297
glioblastoma 12 | 5,635
osteosarcoma 12 | 7,766
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,204
medulloblastoma, large-cell 10 | 6,086
psoriasis 10 | 6,514
Cancer 9 | 2,388
lung carcinoma 9 | 2,755
Breast cancer 8 | 3,469
atypical teratoid / rhabdoid tumor 8 | 4,971
lung cancer 8 | 4,607
malignant mesothelioma 8 | 3,135
subependymal giant cell astrocytoma 8 | 2,230
Astrocytoma, Pilocytic 6 | 3,006
diabetes mellitus 6 | 1,683
invasive ductal carcinoma 6 | 2,867
tuberculosis 6 | 1,963
Kidney cancer 5 | 2,548
adult high grade glioma 5 | 3,701
cutaneous lupus erythematosus 5 | 1,016
gastric carcinoma 5 | 781
group 3 medulloblastoma 5 | 4,002
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,902
lung adenocarcinoma 5 | 2,627
ulcerative colitis 5 | 1,765
Atopic dermatitis 4 | 915
Autosomal recessive predisposition 4 | 1,407
Chronic hepatitis C 4 | 12
Leukemia, Myelocytic, Acute 4 | 120
Leukemia, Myeloid, Acute 4 | 105
Vascular disease 4 | 294
breast carcinoma 4 | 1,589
ependymoma 4 | 4,559
esophageal adenocarcinoma 4 | 696
non-small cell lung cancer 4 | 2,799
oligodendroglioma 4 | 2,768
Alzheimer's disease 3 | 640
Duchenne muscular dystrophy 3 | 587
Liver Cirrhosis, Experimental 3 | 733
Myocardial Reperfusion Injury 3 | 35
Stomach Neoplasms 3 | 287
acute quadriplegic myopathy 3 | 1,133
astrocytic glioma 3 | 2,530
colon cancer 3 | 1,428
cystic fibrosis 3 | 1,629
interstitial cystitis 3 | 2,237
juvenile dermatomyositis 3 | 1,147
pancreatic cancer 3 | 2,322
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,911
posterior fossa group A ependymoma 3 | 456
primary Sjogren syndrome 3 | 710
Abnormality of the fingernails 2 | 51
Arthritis 2 | 276
Bipolar Disorder 2 | 646
Breast Neoplasms 2 | 423
Dermatitis, Allergic Contact 2 | 67
Diabetes Mellitus, Insulin-Dependent 2 | 48
Diabetes Mellitus, Type 1 2 | 43
Disease Progression 2 | 133
Fascioliasis 2 | 17
Heart disease 2 | 288
Mammary Neoplasms 2 | 403
Multiple myeloma 2 | 1,296
Myopathy 2 | 185
Pancreatitis 2 | 118
Proteinuria 2 | 143
Short stature 2 | 514
Sleeping sickness 2 | 37
Toxic encephalopathy 2 | 139
adrenocortical carcinoma 2 | 1,385
aldosterone-producing adenoma 2 | 646
dermatomyositis 2 | 941
interstitial lung disease 2 | 287
non-small cell lung carcinoma 2 | 302
primary pancreatic ductal adenocarcinoma 2 | 1,071
primitive neuroectodermal tumor 2 | 2,957
spina bifida 2 | 1,053
Acquired flat foot 1 | 70
Acro-Osteolysis 1 | 12
Acrocallosal syndrome 1 | 12
Atrophy of alveolar ridges 1 | 1
Calcified choroid plexus 1 | 2
Congenital palmoplantar keratosis 1 | 1
Cycloplegia 1 | 12
Edema 1 | 80
Gingivitis 1 | 28
HAIM-MUNK SYNDROME 1 | 1
Keratosis 1 | 36
Periodontitis, Juvenile 1 | 1
Pimples 1 | 10
Plague 1 | 19
Pleural empyema 1 | 12
Recurrent bacterial skin infections 1 | 8
Short distal phalanges 1 | 49
Skin Abnormalities 1 | 37
Type 1 diabetes mellitus 1 | 106
Waterhouse-Friderichsen syndrome 1 | 9
pustule 1 | 10

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Enzyme 27 | 4,145
Non-IDG 5 | 12,091

GO Function

cysteine-type peptidase activi... 32 | 32
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative inactive cathepsin L-like protein CTSL3P CTSL3P Tdark Enzyme 0.00000 0
Probable ubiquitin carboxyl-terminal hydrolase FAF-Y USP9Y Tbio Enzyme -1.52317 31.8 27
Cathepsin Z CTSZ Tchem Enzyme -1.80363 70.2 233
Sentrin-specific protease 7 SENP7 Tchem Enzyme -1.49048 28.4 171
Cathepsin B CTSB Tchem Enzyme -3.72723 5011.5 448
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Cysteine protease ATG4B ATG4B Tchem Enzyme -1.79492 58.3 416
Pyroglutamyl-peptidase 1-like protein PGPEP1L Tdark Enzyme 0.00000 14