Development Level

Tchem 15 | 1,890
Tbio 14 | 10,625
Tdark 1 | 7,003

IMPC Term

abnormal coat/hair pigmentatio... 1 | 54
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating fructosa... 1 | 31
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 34
decreased prepulse inhibition 1 | 52
decreased total body fat amoun... 1 | 186
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased or absent threshold ... 1 | 128
short tibia 1 | 82

Disease

ovarian cancer 16 | 8,484
glioblastoma 14 | 5,572
osteosarcoma 13 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,289
medulloblastoma, large-cell 12 | 6,234
malignant mesothelioma 11 | 3,162
lung cancer 10 | 4,466
psoriasis 10 | 6,685
atypical teratoid / rhabdoid tumor 9 | 4,369
lung carcinoma 9 | 2,844
subependymal giant cell astrocytoma 9 | 2,287
Cancer 8 | 2,346
Breast cancer 7 | 3,094
pilocytic astrocytoma 7 | 3,086
ulcerative colitis 7 | 2,087
diabetes mellitus 6 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
invasive ductal carcinoma 6 | 2,950
tuberculosis 6 | 1,557
Atopic dermatitis 5 | 944
cutaneous lupus erythematosus 5 | 1,056
gastric carcinoma 5 | 832
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
pediatric high grade glioma 5 | 2,712
posterior fossa group A ependymoma 5 | 1,511
Chronic hepatitis C 4 | 12
Leukemia, Myelocytic, Acute 4 | 113
breast carcinoma 4 | 1,614
cystic fibrosis 4 | 1,665
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,299
juvenile dermatomyositis 4 | 1,189
lung adenocarcinoma 4 | 2,713
non-small cell lung cancer 4 | 2,798
oligodendroglioma 4 | 2,849
primitive neuroectodermal tumor 4 | 3,031
Alzheimer's disease 3 | 644
Carcinoma 3 | 2,147
Duchenne muscular dystrophy 3 | 602
Stomach Neoplasms 3 | 282
Vascular disease 3 | 281
acute quadriplegic myopathy 3 | 1,157
adrenocortical carcinoma 3 | 1,427
colon cancer 3 | 1,475
ependymoma 3 | 2,514
group 4 medulloblastoma 3 | 1,875
pancreatic cancer 3 | 2,300
primary Sjogren syndrome 3 | 789
primary pancreatic ductal adenocarcinoma 3 | 1,271
Arthritis 2 | 248
Dermatitis, Allergic Contact 2 | 66
Disease Progression 2 | 125
Fascioliasis 2 | 18
Malaria 2 | 140
Mammary Neoplasms 2 | 410
Multiple myeloma 2 | 1,327
Myocardial Reperfusion Injury 2 | 34
Myopathy 2 | 128
Pancreatitis 2 | 97
Proteinuria 2 | 63
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
dermatomyositis 2 | 933
group 3 medulloblastoma 2 | 2,254
inflammatory breast cancer 2 | 404
interstitial lung disease 2 | 291
medulloblastoma 2 | 1,524
non diabetic and post-ischemic heart failure 2 | 200
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
posterior fossa group B ependymoma 2 | 1,530
sonic hedgehog group medulloblastoma 2 | 1,482
spina bifida 2 | 1,064
Antiphospholipid syndrome 1 | 18
Bladder Neoplasm 1 | 109
Carcinoma, Transitional Cell 1 | 31
Chagas disease 1 | 34
Chronic Lymphocytic Leukemia 1 | 242
Colorectal Neoplasms 1 | 217
Exanthem 1 | 39
Fungal meningitis 1 | 7
Gaucher disease type 1 1 | 171
Infertility 1 | 163
Lung Neoplasms 1 | 171
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 1 | 12
Melanoma 1 | 261
Myopia 1 | 99
Narcolepsy 1 | 58
Necrosis 1 | 51
Osteonecrosis 1 | 25
Osteoporosis 1 | 257
Papillon-Lefevre disease 1 | 4
Paratyphoid fever 1 | 10
Turner syndrome 1 | 31
Uterine Cervical Neoplasm 1 | 21
Yellow fever 1 | 14
limb-girdle muscular dystrophy 1 | 36
permanent atrial fibrillation 1 | 44

Tissue

Blood and immune system 30 | 17,995
Cardiovascular System 30 | 17,958
Digestive Tract 30 | 18,473
Female tissues 30 | 18,647
Liver and Pancreas 30 | 18,136
Male tissues 30 | 17,969
Nervous System 30 | 18,561
Urinary Tract 30 | 18,444
Endocrine System 29 | 18,512
Respiratory system 29 | 17,484
Skin and soft tissues 29 | 18,115

Target Family

Enzyme 25 | 4,146
Non-IDG 5 | 11,971

GO Function

cysteine-type peptidase activi... 30 | 30
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cysteine protease ATG4A ATG4A Tbio Enzyme -0.98696 7.89 199
Probable ubiquitin carboxyl-terminal hydrolase FAF-X USP9X Tbio Enzyme -1.79254 69.5 187
Caspase-5 CASP5 Tchem Enzyme -1.99198 92.6 359
Bleomycin hydrolase BLMH Tbio Enzyme -1.93422 85.3 168
Pyroglutamyl-peptidase 1 PGPEP1 Tbio Enzyme -2.36183 239.8 76
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.22597 1740.5 143
Cysteine protease ATG4B ATG4B Tchem Enzyme -1.63370 46.4 338
Pyroglutamyl-peptidase 1-like protein PGPEP1L Tdark Enzyme 0.00000 10
Calpain-2 catalytic subunit CAPN2 Tchem Non-IDG -1.66858 45.4 184
Ubiquitin carboxyl-terminal hydrolase 21 USP21 Tbio Enzyme -1.62273 43.6 243