Development Level

Tbio 2 | 11,445

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased circulating insulin ... 1 | 76
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
psoriasis 2 | 6,694
Abdominal pain, episodic 1 | 9
Acromegaly 1 | 51
Adenoma 1 | 167
Adrenal cortical adenoma 1 | 19
Alcoholic Intoxication, Chronic 1 | 289
Alcoholism 1 | 45
Angiofibroma 1 | 7
Ataxia telangiectasia 1 | 34
Bladder Neoplasm 1 | 112
Cancer 1 | 2,499
Carcinoma 1 | 11,493
Carcinoma, Transitional Cell 1 | 32
Colonic Neoplasms 1 | 142
Diarrhea 1 | 253
Duchenne muscular dystrophy 1 | 601
Esophageal Squamous Cell Carcinoma 1 | 77
Esophagitis 1 | 35
Growth hormone excess 1 | 14
HIV Infections 1 | 102
Heart conduction disease 1 | 83
Hypercalcemia 1 | 59
Hyperinsulinaemic hypoglycaemia 1 | 16
Hyperinsulinemia, fasting 1 | 7
Hyperparathyroidism 1 | 48
Increased serum parathyroid hormone 1 | 14
Insulinoma 1 | 24
Intestinal Neoplasms 1 | 12
Kidney Diseases 1 | 114
Liver Cirrhosis, Experimental 1 | 769
Lung Neoplasms 1 | 232
Mesothelioma, Malignant 1 | 105
Multiple Endocrine Neoplasia Type 1 1 | 29
Muscular Dystrophy, Facioscapulohumeral 1 | 12
Non-Functioning Pituitary Gland Neoplasm 1 | 6
Papilloma 1 | 44
Parathyroid Adenoma 1 | 19
Parathyroid hyperplasia 1 | 6
Peptic Ulcer 1 | 27
Pituitary growth hormone cell adenoma 1 | 8
Prolactinoma 1 | 11
Prostatic Neoplasms 1 | 495
Reperfusion Injury 1 | 86
Squamous cell carcinoma of esophagus 1 | 77
Stomach Neoplasms 1 | 300
Subcutaneous lipomas 1 | 9
Thyroid Gland Follicular Adenoma 1 | 9
Urinary Bladder Neoplasms 1 | 114
Zollinger-Ellison syndrome 1 | 18
acute quadriplegic myopathy 1 | 1,158
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
ductal carcinoma in situ 1 | 1,745
gastric cancer 1 | 459
glioblastoma 1 | 5,792
intermittent abdominal pain 1 | 9
juvenile dermatomyositis 1 | 1,187
limb girdle muscular dystrophy 2A 1 | 213
lung cancer 1 | 4,740
non diabetic and post-ischemic heart failure 1 | 200
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pituitary cancer 1 | 1,972
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

cyclin-dependent protein kinas... 2 | 2
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase 20 CDK20 Tbio Kinase -1.82269 67.7 248
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509