Development Level

Tbio 19 | 11,445
Tchem 9 | 1,598
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal epididymis morphology 2 | 42
abnormal heart morphology 2 | 162
enlarged epididymis 2 | 31
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased IgE level 1 | 6
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
shortened RR interval 1 | 17
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 22 | 11,493
ovarian cancer 20 | 8,520
Cancer 15 | 2,499
glioblastoma 15 | 5,792
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
adult high grade glioma 11 | 3,801
lung cancer 11 | 4,740
malignant mesothelioma 11 | 3,232
osteosarcoma 11 | 7,950
psoriasis 11 | 6,694
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
ependymoma 9 | 4,679
oligodendroglioma 9 | 2,850
Breast cancer 8 | 3,578
Astrocytoma, Pilocytic 7 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Multiple myeloma 6 | 1,332
astrocytoma 6 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
Kidney cancer 5 | 2,613
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Adenoma 4 | 167
Carcinoma, Hepatocellular 4 | 228
Intellectual disability 4 | 1,016
Liver carcinoma 4 | 240
astrocytic glioma 4 | 2,597
lung adenocarcinoma 4 | 2,716
medulloblastoma 4 | 720
primary pancreatic ductal adenocarcinoma 4 | 1,109
ulcerative colitis 4 | 1,819
Insulinoma 3 | 24
Melanoma 3 | 711
Pick disease 3 | 1,894
Rheumatoid arthritis 3 | 1,191
Stomach Neoplasms 3 | 300
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074
Abdominal pain, episodic 2 | 9
Acromegaly 2 | 51
Adrenal cortical adenoma 2 | 19
Atopic dermatitis 2 | 952
Basal cell carcinoma 2 | 54
Brain Neoplasms 2 | 33
Breast Neoplasms 2 | 445
Carcinoma, Basal Cell 2 | 28
Chloracne 2 | 32
Chronic obstructive pulmonary disease 2 | 184
Congenital hereditary endothelial dystrophy of cornea 2 | 8
Diarrhea 2 | 253
Dilated ventricles (finding) 2 | 121
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Esophageal Squamous Cell Carcinoma 2 | 77
Esophagitis 2 | 35
HIV Infections 2 | 102
Hormone receptor positive malignant neoplasm of breast 2 | 10
Hypercalcemia 2 | 59
Hyperparathyroidism 2 | 48
Increased serum parathyroid hormone 2 | 14
Intestinal Neoplasms 2 | 12
Liver Cirrhosis, Experimental 2 | 769
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Mammary Neoplasms, Experimental 2 | 154
Melanocytic nevus 2 | 43
Mesothelioma, Malignant 2 | 105
Multiple endocrine neoplasia type 2A 2 | 20
Neuronal ceroid lipofuscinosis 2 2 | 17
Parkinson's disease 2 | 392
Prolactinoma 2 | 11
Prostatic Neoplasms 2 | 495
Squamous cell carcinoma of esophagus 2 | 77
Stomach cancer 2 | 30
Systemic lupus erythematosus 2 | 194
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
hereditary spastic paraplegia 2 | 318
intermittent abdominal pain 2 | 9
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
sarcoidosis 2 | 370

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Cardiovascular System 30 | 15,192
Female tissues 30 | 17,400

Target Family

Non-IDG 13 | 12,091
Kinase 11 | 634
Enzyme 5 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

GO Function

cyclin binding 31 | 31
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein INCA1 INCA1 Tbio Non-IDG -1.27674 18.1 105
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Protein PROCA1 PROCA1 Tbio Non-IDG -0.54042 3.33 57
F-box only protein 31 FBXO31 Tbio Non-IDG -0.38620 2.03 157
Ubiquitin carboxyl-terminal hydrolase 2 USP2 Tbio Enzyme -1.91393 84.9 300
Cyclin-G-associated kinase GAK Tchem Kinase -1.85747 68.2 231
DNA polymerase nu POLN Tbio Enzyme -2.17621 148.9 60
MyoD family inhibitor domain-containing protein MDFIC Tbio Non-IDG -2.90969 749.0 122
Insulinoma-associated protein 1 INSM1 Tbio Transcription Factor -2.56531 362.4 56
Cullin-3 CUL3 Tbio Non-IDG -3.26322 1670.8 307