Development Level

Tbio 13 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

abnormal response to tactile s... 1 | 17
decreased circulating chloride... 1 | 30
decreased circulating triglyce... 1 | 79
increased circulating chloride... 1 | 41

Disease

ovarian cancer 10 | 8,520
osteosarcoma 8 | 7,950
Cancer 6 | 2,499
psoriasis 6 | 6,694
Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
subependymal giant cell astrocytoma 4 | 2,287
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Cockayne syndrome 2 | 60
Dystonia 2 | 164
Multiple myeloma 2 | 1,332
Neuronal ceroid lipofuscinosis 2 2 | 17
Parkinson's disease 2 | 392
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
atypical teratoid / rhabdoid tumor 2 | 5,112
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
ATRIOVENTRICULAR CANAL DEFECT 1 | 17
Abnormality of metabolism/homeostasis 1 | 134
Adult onset 1 | 82
Agoraphobia 1 | 21
Atrial Septal Defects 1 | 85
Autistic Disorder 1 | 364
Big calvaria 1 | 147
Bradykinesia 1 | 34
Broad forehead 1 | 59
Bronchioloalveolar Adenocarcinoma 1 | 14
Cataract 7 1 | 32
Cerebellar hypoplasia and atrophy 1 | 41
Colonic Neoplasms 1 | 142
Congenital Camptodactyly 1 | 40
Death in early childhood 1 | 82
Death in infancy 1 | 82
Delusional disorder 1 | 13
Dementia 1 | 175
Disease Progression 1 | 136
Downward slant of palpebral fissure 1 | 158
Dysgerminoma 1 | 11
Dystonic disease 1 | 106
Endocardial Cushion Defects 1 | 17
Frontal bossing 1 | 157
Gliosis in the substantia nigra 1 | 3
Hereditary spherocytosis 1 | 16
High, narrow palate 1 | 32
Hyperkyphosis 1 | 111
Hyperreflexia 1 | 209
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Kyphosis deformity of spine 1 | 114
Leprosy 1 | 73
Liver Cirrhosis 1 | 181
Low posterior hairline 1 | 52
Lung Neoplasms 1 | 232
Manganese Poisoning 1 | 11
Multiple system atrophy 1 | 29
Muscle Rigidity 1 | 49
Nerve Degeneration 1 | 121
Neurodegenerative disease 1 | 414
Ovarian Cysts 1 | 41
Ovarian Neoplasms 1 | 102
PARKINSON DISEASE, LATE-ONSET 1 | 20
Parkinson Disease 1 | 64
Parkinsonian Disorders 1 | 56
Paronychia 1 | 7
Poor speech 1 | 37
Postural instability 1 | 19
Problems speaking 1 | 37
Prominent back of the head 1 | 21
Prominent occiput 1 | 21
Protrusion of tongue 1 | 11
Pulmonary Stenosis 1 | 45
Rectal neoplasm 1 | 6
Recurrent respiratory infections 1 | 141
Short distal phalanges 1 | 50
Short philtrum 1 | 53
Speech Disorders 1 | 58
Stevens-Johnson syndrome 1 | 92
Stomach Neoplasms 1 | 300
Tetralogy of Fallot 1 | 63
Toxic encephalopathy 1 | 141
Tremor 1 | 113
X- linked recessive 1 | 110
Xeroderma pigmentosum 1 | 43
posterior fossa group A ependymoma 1 | 468
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 4 | 4,145

GO Function

cullin family protein binding 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DCN1-like protein 5 DCUN1D5 Tdark Non-IDG -0.30103 2.00 14
BTB/POZ domain-containing protein KCTD5 KCTD5 Tbio Non-IDG -1.70628 50.2 52
Anaphase-promoting complex subunit 11 ANAPC11 Tbio Enzyme -1.27406 17.9 239
DCN1-like protein 3 DCUN1D3 Tdark Non-IDG -0.38917 2.58 50
BTB/POZ domain-containing protein KCTD6 KCTD6 Tbio Non-IDG -0.10266 1.31 112
BTB/POZ domain-containing protein KCTD21 KCTD21 Tbio Non-IDG 0.60 0.27 84
DCN1-like protein 1 DCUN1D1 Tbio Non-IDG -1.35710 26.1 224
DNA damage-binding protein 1 DDB1 Tbio Non-IDG -2.34719 202.5 353
BTB/POZ domain-containing protein KCTD2 KCTD2 Tdark Non-IDG -0.29922 2.15 61
S-phase kinase-associated protein 1 SKP1 Tbio Enzyme -2.57150 310.1 381