Development Level

Tbio 14 | 11,445
Tclin 11 | 613
Tchem 7 | 1,598

IMPC Phenotype

abnormal bone structure 2 | 187
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal craniofacial morpholo... 1 | 33
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal gait 1 | 69
anophthalmia 1 | 33
decreased T cell number 1 | 15
decreased circulating alkaline... 1 | 46
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
increased CD4-positive, alpha ... 1 | 4
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
limb grasping 1 | 41
microphthalmia 1 | 26
tremors 1 | 39

Disease

Carcinoma 22 | 11,493
Cancer 18 | 2,499
osteosarcoma 17 | 7,950
glioblastoma 16 | 5,792
psoriasis 15 | 6,694
interstitial cystitis 14 | 2,312
invasive ductal carcinoma 14 | 2,951
Astrocytoma, Pilocytic 12 | 3,081
cutaneous lupus erythematosus 12 | 1,057
lung cancer 12 | 4,740
lung carcinoma 12 | 2,843
ovarian cancer 12 | 8,520
adult high grade glioma 11 | 3,801
tuberculosis 11 | 2,010
Rheumatoid arthritis 10 | 1,191
ulcerative colitis 10 | 1,819
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
malignant mesothelioma 9 | 3,232
Breast cancer 8 | 3,578
Liver Cirrhosis, Experimental 8 | 769
breast carcinoma 8 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Kidney cancer 7 | 2,613
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
Multiple Sclerosis 6 | 540
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
pituitary cancer 6 | 1,972
primary Sjogren syndrome 6 | 735
primitive neuroectodermal tumor 6 | 3,035
subependymal giant cell astrocytoma 6 | 2,287
Arthritis, Rheumatoid 5 | 174
Asthma 5 | 385
Human immunodeficiency virus infectious disease 5 | 138
Lung disease 5 | 142
medulloblastoma 5 | 720
Arthritis 4 | 290
Atopic dermatitis 4 | 952
Hypersensitivity reaction type II disease 4 | 253
Neoplasm Metastasis 4 | 168
Schizophrenia 4 | 1,160
dermatomyositis 4 | 966
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
Anemia 3 | 365
Autistic Disorder 3 | 364
Autosomal recessive predisposition 3 | 1,442
Cerebrovascular disease 3 | 238
Gliosis 3 | 56
Hypertension 3 | 396
Prostatic Neoplasms 3 | 495
Type 1 Diabetes Mellitus Treatment Adjunct 3 | 4
Type 2 Diabetes Mellitus Treatment Adjunct 3 | 7
adrenocortical carcinoma 3 | 1,428
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
nephrosclerosis 3 | 333
pancreatic cancer 3 | 2,398
sarcoidosis 3 | 370
Allergic hypersensitivity disease 2 | 126
Alzheimer's disease 2 | 658
Arthritis, Juvenile 2 | 126
Atherosclerosis 2 | 291
Cerebrovascular accident 2 | 63
Cholestasis 2 | 155
Dementia 2 | 175
Dermatitis 2 | 157
Down syndrome 2 | 499
Endometriosis 2 | 540
Hepatitis B 2 | 108
Inflammatory bowel disease 2 | 151
Influenza 2 | 142
Juvenile arthritis 2 | 126
Kidney disease 2 | 430
Liver cancer 2 | 604
Malaria 2 | 160
Mental Depression 2 | 333
Miller-Dieker lissencephaly syndrome 2 | 19
Neoplasm Invasiveness 2 | 161
Stroke 2 | 33
Type 2 diabetes mellitus 2 | 272
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
chronic lymphosyte leukemia 2 | 204
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
nasopharyngeal carcinoma 2 | 1,058
non diabetic and post-ischemic heart failure 2 | 200
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Digestive Tract 32 | 17,369
Skin and soft tissues 32 | 17,230
Endocrine System 31 | 18,159
Liver and Pancreas 31 | 16,750
Urinary Tract 31 | 16,678
Blood and immune system 30 | 16,909
Female tissues 30 | 17,400
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 29 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 26 | 12,091
GPCR 5 | 408
Kinase 1 | 634

GO Function

coreceptor activity 32 | 32
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Transmembrane and immunoglobulin domain-containing protein 2 TMIGD2 Tbio Non-IDG -0.76538 6.16 140
Leukocyte immunoglobulin-like receptor subfamily A member 4 LILRA4 Tbio Non-IDG -0.86432 8.22 140
Integrin alpha-4 ITGA4 Tclin Non-IDG -2.53262 310.4 1312
T-cell surface glycoprotein CD8 alpha chain CD8A Tbio Non-IDG -2.37172 222.6 3514
Transforming growth factor beta receptor type 3 TGFBR3 Tbio Non-IDG -1.92250 80.6 270
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
Receptor activity-modifying protein 2 RAMP2 Tclin Non-IDG -1.88714 81.5 157
C-X-C chemokine receptor type 4 CXCR4 Tclin GPCR -3.41606 2525.3 1240