Development Level

Tbio 39 | 11,651
Tchem 13 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

abnormal sleep behavior 2 | 70
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart left ventricle ... 1 | 16
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
convulsive seizures 1 | 13
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
increased body length 1 | 32
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 28 | 8,520
Carcinoma 26 | 11,493
psoriasis 24 | 6,694
osteosarcoma 20 | 7,950
lung cancer 18 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
atypical teratoid / rhabdoid tumor 16 | 5,112
Breast cancer 15 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
malignant mesothelioma 15 | 3,232
Cancer 13 | 2,499
glioblastoma 12 | 5,792
medulloblastoma, large-cell 12 | 6,241
non-small cell lung cancer 12 | 2,890
pancreatic cancer 12 | 2,398
Autosomal recessive predisposition 11 | 1,442
Depressive disorder 11 | 409
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
lung adenocarcinoma 11 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
tuberculosis 11 | 2,010
ulcerative colitis 11 | 1,819
adult high grade glioma 10 | 3,801
lung carcinoma 10 | 2,843
primitive neuroectodermal tumor 10 | 3,035
Alzheimer's disease 9 | 658
Astrocytoma, Pilocytic 9 | 3,081
Hypertension 9 | 396
Hypertensive disease 9 | 292
Menkes disease 9 | 19
breast carcinoma 9 | 1,638
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
interstitial cystitis 9 | 2,312
Schizophrenia 8 | 1,160
ductal carcinoma in situ 8 | 1,745
invasive ductal carcinoma 8 | 2,951
Anemia 7 | 365
Atherosclerosis 7 | 291
Atopic dermatitis 7 | 952
Hepatitis, Chronic 7 | 23
Liver Cirrhosis 7 | 181
Neurodegenerative disease 7 | 414
Pick disease 7 | 1,894
Toxic encephalopathy 7 | 141
Wilson disease 7 | 16
cutaneous lupus erythematosus 7 | 1,057
oligodendroglioma 7 | 2,850
Brain Ischemia 6 | 110
Dementia 6 | 175
Epilepsy 6 | 792
Kidney cancer 6 | 2,613
Melanoma 6 | 711
Seizures 6 | 596
Vascular disease 6 | 319
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
esophageal adenocarcinoma 6 | 737
primary pancreatic ductal adenocarcinoma 6 | 1,109
Amyotrophic lateral sclerosis 5 | 451
Brain disease 5 | 96
Chemical and Drug Induced Liver Injury 5 | 195
Disease Models, Animal 5 | 155
Fatigue 5 | 182
Hepatolenticular Degeneration 5 | 24
Intellectual disability 5 | 1,016
Liver Neoplasms, Experimental 5 | 59
Mental Depression 5 | 333
Multiple myeloma 5 | 1,332
Parkinson's disease 5 | 392
acute myeloid leukemia 5 | 783
colon cancer 5 | 1,478
interstitial lung disease 5 | 298
mucosa-associated lymphoid tissue lymphoma 5 | 484
pituitary cancer 5 | 1,972
Alcoholic Intoxication, Chronic 4 | 289
Arthritis 4 | 290
Bladder Neoplasm 4 | 112
Blepharoptosis 4 | 231
Breast Neoplasms 4 | 445
Colonic Neoplasms 4 | 142
Coronary artery disease 4 | 268
Dull intelligence 4 | 645
Heart failure 4 | 162
Hepatitis B 4 | 108
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Mammary Neoplasms 4 | 425
Nerve Degeneration 4 | 121
Osteoporosis 4 | 363
Parkinson Disease 4 | 64
Proteinuria 4 | 144
Rheumatoid arthritis 4 | 1,191
Thrombocytopenia 4 | 197
Urinary Bladder Neoplasms 4 | 114
Waldenstrons macroglobulinemia 4 | 765
fibroadenoma 4 | 559
gastric carcinoma 4 | 807

Tissue

Endocrine System 53 | 18,159
Female tissues 53 | 17,400
Skin and soft tissues 53 | 17,230
Blood and immune system 52 | 16,909
Digestive Tract 51 | 17,369
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Urinary Tract 51 | 16,678
Nervous System 50 | 16,725
Respiratory system 50 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Enzyme 27 | 4,145
Non-IDG 23 | 12,091
Transcription Factor 3 | 1,400
Ion Channel 1 | 344

GO Function

copper ion binding 54 | 54
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.24186 173.0 274
Zinc finger protein SNAI3 SNAI3 Tbio Transcription Factor -1.02195 9.05 94
L-dopachrome tautomerase DCT Tbio Enzyme -2.30152 161.6 299
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Alpha-synuclein SNCA Tchem Non-IDG -3.63937 4224.9 1813
Laccase domain-containing protein 1 LACC1 Tbio Enzyme -1.14478 13.5 52
Angiogenin ANG Tbio Enzyme -2.88667 826.6 256
Interleukin-1 alpha IL1A Tchem Non-IDG -3.56722 3688.9 1000
Glypican-1 GPC1 Tbio Non-IDG -2.38207 232.3 202