Development Level

Tbio 6 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

decreased erythrocyte cell num... 1 | 62
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 96
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 10 | 11,493
ovarian cancer 7 | 8,520
Cancer 6 | 2,499
osteosarcoma 6 | 7,950
Osteoporosis 5 | 363
lung adenocarcinoma 5 | 2,716
cutaneous lupus erythematosus 4 | 1,057
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Cleft Lip 3 | 141
Cleft Palate 3 | 271
Hemochromatosis 3 | 54
Hemochromatosis type 1 3 | 9
Mammary Neoplasms 3 | 425
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
pituitary cancer 3 | 1,972
Alzheimer's disease 2 | 658
Anemia 2 | 365
Ankylosing spondylitis 2 | 140
Ankylosis 2 | 28
Atopic dermatitis 2 | 952
Atransferrinemia 2 | 8
Autosomal recessive predisposition 2 | 1,442
Brachydactyly 2 | 156
Cognitive delay 2 | 608
Congenital Epicanthus 2 | 177
Downward slant of palpebral fissure 2 | 158
Elevated hepatic transaminases 2 | 81
Endometriosis 2 | 540
Fractures, Bone 2 | 13
Global developmental delay 2 | 608
Hemolytic anemia 2 | 77
Hepatic enzyme increased 2 | 81
Hyperferritinaemia 2 | 14
Hyperpigmentation 2 | 37
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypotrophic malar bone 2 | 129
Increased ferritin 2 | 14
Juvenile osteoporosis 2 | 4
Kidney cancer 2 | 2,613
Liver Cirrhosis 2 | 181
Liver Dysfunction 2 | 99
Liver disease 2 | 237
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Malar flattening 2 | 129
Mental and motor retardation 2 | 608
Neurodegenerative disease 2 | 414
Orbital separation excessive 2 | 244
Osteoarthritis 2 | 184
Osteoporosis, Juvenile 2 | 4
Otosclerosis 2 | 15
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Peripheral vascular disease 2 | 87
Schizophrenia 2 | 1,160
Serum ferritin increased 2 | 14
Short stature 2 | 531
Subclinical abnormal liver function tests 2 | 81
Thalassemia 2 | 53
Transaminases increased 2 | 81
Vascular disease 2 | 319
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
medulloblastoma, large-cell 2 | 6,241
pediatric high grade glioma 2 | 1,064
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormality of the hypothalamus-pituitary axis 1 | 12
Arthropathy 1 | 43
Atrophy of testis 1 | 14
Autosomal dominant late onset Parkinson disease 1 | 7
Cleft uvula 1 | 27
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Erectile dysfunction 1 | 32
Focal dermal hypoplasia 1 | 8
Hypoplasia of scrotum 1 | 24
Leprosy 1 | 73
Movement disease 1 | 11
Prolactinoma 1 | 11
Simple syndactyly of toes, first web space 1 | 23
Single transverse palmar crease 1 | 29
Temtamy preaxial brachydactyly syndrome 1 | 3
Thin hypoplastic alae nasi 1 | 51
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Blood and immune system 9 | 16,909
Endocrine System 9 | 18,159
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Liver and Pancreas 8 | 16,750
Respiratory system 8 | 16,393
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Function

co-receptor binding 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.65728 4647.9 684
Transferrin receptor protein 2 TFR2 Tbio Enzyme -2.11882 135.2 149
Dickkopf-related protein 1 DKK1 Tchem Non-IDG -2.79271 621.8 694
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.21660 1658.5 540
Hereditary hemochromatosis protein HFE Tbio Non-IDG -3.32815 2229.5 248
Neogenin NEO1 Tbio Non-IDG -2.07465 120.2 123
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Tchem Kinase -3.07199 1241.4 740
Protein Wnt-9b WNT9B Tbio Non-IDG -1.44759 27.3 98
Protein Wnt-3a WNT3A Tchem Non-IDG -2.74001 473.8 421
Dickkopf-related protein 2 DKK2 Tbio Non-IDG -1.61934 41.9 227