Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating unsatura... 1 | 2
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
pallor 1 | 34

Disease

ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
glioblastoma 6 | 5,792
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
Carcinoma 4 | 11,493
ependymoma 4 | 4,679
lung cancer 4 | 4,740
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
Alzheimer's disease 3 | 658
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
ductal carcinoma in situ 3 | 1,745
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Gaucher disease type 1 2 | 180
Leber congenital amaurosis 2 | 69
astrocytic glioma 2 | 2,597
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Alcohol abuse 1 | 50
Alzheimer Disease 1 | 83
Amyloidosis 1 | 67
Angina Pectoris 1 | 32
Aortic aneurysm 1 | 38
Arcus Senilis 1 | 11
Arcus juvenilis 1 | 5
Autoimmune thyroiditis 1 | 27
Cardiovascular system disease 1 | 246
Chronic obstructive pulmonary disease 1 | 184
Chronic tic disorder 1 | 8
Common Migraine 1 | 7
Coronary Arteriosclerosis 1 | 6
Coronary Disease 1 | 25
Coronary artery disease 1 | 268
Coronary heart disease 1 | 16
Dementia 1 | 175
Down syndrome 1 | 499
Dyslipidemias 1 | 27
Dyspnea 1 | 76
Endometrial cancer 1 | 311
Familial hypocalciuric hypercalcemia 1 | 20
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Hypercholesterolemia 1 | 44
Hyperlipidemia 1 | 43
Hyperplasia 1 | 27
Impaired left ventricular function 1 | 16
Large intestine cancer 1 | 126
Left-Sided Heart Failure 1 | 16
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Lipid metabolism disorder 1 | 114
Liver cancer 1 | 604
Lung Neoplasms 1 | 232
Lymphoid leukemia 1 | 160
Major Depressive Disorder 1 | 301
Melanoma 1 | 711
Migraine Disorders 1 | 76
Migraine without Aura 1 | 11
Myocardial Infarction 1 | 151
Non-alcoholic Fatty Liver Disease 1 | 42
Nonsyndromic deafness 1 | 142
Plaque build-up in arteries supplying blood to heart 1 | 6
Q fever 1 | 15
Renal Artery Stenosis 1 | 9
Serum cholesterol raised 1 | 22
Skin cancer 1 | 469
Steatohepatitis 1 | 44
Sudden Cardiac Death 1 | 29
Tic disorder 1 | 8
Unipolar Depression 1 | 250
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
acute T cell leukemia 1 | 17
breast carcinoma 1 | 1,638
fibroadenoma 1 | 559
nasopharyngeal carcinoma 1 | 1,058
osteoporosis-pseudoglioma syndrome 1 | 9
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
progressive supranuclear palsy 1 | 676
sarcoidosis 1 | 370
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 6 | 12,091
GPCR 1 | 408

GO Function

clathrin heavy chain binding 7 | 7
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell migration-inducing and hyaluronan-binding protein CEMIP Tbio Non-IDG -1.58210 41.5 144
Clathrin light chain A CLTA Tbio Non-IDG -1.32676 16.0 244
Clathrin light chain B CLTB Tbio Non-IDG -2.29105 193.6 153
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.06808 938.9 585
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130
Prolow-density lipoprotein receptor-related protein 1 LRP1 Tbio Non-IDG -2.52012 357.1 711
Protein GPR107 GPR107 Tdark GPCR -0.45738 4.03 113