Development Level

Tbio 35 | 11,445
Tdark 7 | 6,588
Tchem 3 | 1,598

IMPC Phenotype

increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97

Disease

Carcinoma 38 | 11,493
atypical teratoid / rhabdoid tumor 23 | 5,112
medulloblastoma, large-cell 23 | 6,241
glioblastoma 22 | 5,792
osteosarcoma 22 | 7,950
group 3 medulloblastoma 21 | 4,104
ovarian cancer 21 | 8,520
oligodendroglioma 19 | 2,850
ependymoma 18 | 4,679
psoriasis 18 | 6,694
Astrocytoma, Pilocytic 17 | 3,081
lung carcinoma 16 | 2,843
adult high grade glioma 15 | 3,801
astrocytic glioma 15 | 2,597
primitive neuroectodermal tumor 12 | 3,035
lung cancer 11 | 4,740
Breast cancer 10 | 3,578
Pick disease 10 | 1,894
pituitary cancer 10 | 1,972
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
subependymal giant cell astrocytoma 9 | 2,287
lung adenocarcinoma 8 | 2,716
invasive ductal carcinoma 7 | 2,951
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Kidney cancer 6 | 2,613
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
malignant mesothelioma 6 | 3,232
Alzheimer's disease 5 | 658
Cataract 8 multiple types 5 | 33
Parkinson's disease 5 | 392
ductal carcinoma in situ 5 | 1,745
non-small cell lung cancer 5 | 2,890
Down syndrome 4 | 499
Griscelli syndrome 4 | 24
Melanoma 4 | 711
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
Skin cancer 4 | 469
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
nasopharyngeal carcinoma 4 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Common variable immunodeficiency 3 | 101
Schizophrenia 3 | 1,160
active ulcerative colitis 3 | 764
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive limb-girdle muscular dystrophy type 2B 2 | 5
Bipolar Disorder 2 | 666
Botulism 2 | 24
Cancer 2 | 2,499
Chronic Lymphocytic Leukemia 2 | 262
Chronic obstructive pulmonary disease 2 | 184
Dementia 2 | 175
Depressive Symptoms 2 | 28
Endometriosis 2 | 540
Huntington's disease 2 | 76
Hypertension 2 | 396
Hypertensive disease 2 | 292
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
atypical teratoid/rhabdoid tumor 2 | 357
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
posterior fossa group B ependymoma 2 | 416
substance-related disorder 2 | 162
ulcerative colitis 2 | 1,819
Autoimmune thyroiditis 1 | 27
Celiac disease 1 | 116
Chronic tic disorder 1 | 8
Ciliopathy 1 | 71
Fundus dystrophy 1 | 83
Hyperlipidemia 1 | 43
Hypertrophy 1 | 17
Malignant tumor of prostate 1 | 26
Meniere's disease 1 | 24
Multiple system atrophy 1 | 29
Nephrotic Syndrome 1 | 78
PARKINSON DISEASE, LATE-ONSET 1 | 20
Parkinsonian Disorders 1 | 56
Retinitis pigmentosa 25 1 | 9
Retinitis pigmentosa 28 1 | 19
Scrapie 1 | 17
Serum cholesterol raised 1 | 22
Steatohepatitis 1 | 44

Tissue

Urinary Tract 43 | 16,678
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 39 | 16,393
Skin and soft tissues 39 | 17,230
Blood and immune system 36 | 16,909
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 41 | 12,091
Ion Channel 2 | 344
Epigenetic 1 | 242
Kinase 1 | 634

GO Function

clathrin binding 45 | 45
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synaptotagmin-15 SYT15 Tdark Non-IDG -0.22617 1.25 9
Synaptotagmin-2 SYT2 Tbio Non-IDG -1.93503 86.7 222
Sodium channel and clathrin linker 1 SCLT1 Tdark Non-IDG -0.50820 2.61 97
Synaptotagmin-like protein 2 SYTL2 Tbio Non-IDG -1.27949 19.5 60
Synaptotagmin-7 SYT7 Tbio Non-IDG -1.75931 60.3 170
Synaptotagmin-like protein 3 SYTL3 Tbio Non-IDG -1.02669 10.4 84
Delta and Notch-like epidermal growth factor-related receptor DNER Tbio Non-IDG -1.65805 49.1 185
Neurocalcin-delta NCALD Tbio Non-IDG -1.30940 20.7 102
Synaptotagmin-14 SYT14 Tdark Non-IDG -0.71321 4.64 25
Synaptotagmin-8 SYT8 Tbio Non-IDG -0.75787 4.64 73