Development Level

Tbio 6 | 11,445

IMPC Phenotype

abnormal lens morphology 1 | 81
cardiovascular system phenotyp... 1 | 36
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
thrombocytopenia 1 | 56

Disease

osteosarcoma 6 | 7,950
Carcinoma 5 | 11,493
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Cancer 3 | 2,499
adrenocortical carcinoma 3 | 1,428
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
Alzheimer's disease 2 | 658
Down syndrome 2 | 499
Pilocytic astrocytoma 2 | 56
Rheumatoid arthritis 2 | 1,191
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Alzheimer Disease 1 | 83
Angina Pectoris 1 | 32
Atherosclerosis 1 | 291
Atherosclerosis of aorta 1 | 5
Atopic dermatitis 1 | 952
Autoimmune thyroiditis 1 | 27
Bipolar Disorder 1 | 666
Cataract 8 multiple types 1 | 33
Chronic tic disorder 1 | 8
Common variable immunodeficiency 1 | 101
Coronary Arteriosclerosis 1 | 6
Dementia 1 | 175
Dyspnea 1 | 76
Familial hypercholesterolemia - homozygous 1 | 7
Familial hyperlipidemia 1 | 6
Gaucher disease type 1 1 | 180
Globe disease 1 | 67
Gout 1 | 106
Heart murmur 1 | 5
Huntington's disease 1 | 76
Hypercholesterolemia 1 | 44
Hypercholesterolemia, Familial 1 | 23
Hyperlipidemia 1 | 43
Hyperlipoproteinemia Type IIa 1 | 11
Impaired left ventricular function 1 | 16
Kidney disease 1 | 430
Left-Sided Heart Failure 1 | 16
Leukemia, Acute Myeloid 1 | 17
Leukemia, Myelocytic, Acute 1 | 120
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Experimental 1 | 769
Low density lipoprotein increased 1 | 8
Major Depressive Disorder 1 | 301
Malignant tumor of prostate 1 | 26
Myocardial Infarction 1 | 151
Neurodegenerative disease 1 | 414
Parkinson's disease 1 | 392
Pick disease 1 | 1,894
Plaque build-up in arteries supplying blood to heart 1 | 6
Renal Artery Stenosis 1 | 9
Scrapie 1 | 17
Serum cholesterol raised 1 | 22
Sitosterolemia 1 | 9
Steatohepatitis 1 | 44
Subvalvular aortic stenosis 1 | 4
Sudden Cardiac Death 1 | 29
Thyroid lymphoma 1 | 1
Tic disorder 1 | 8
Unipolar Depression 1 | 250
acute T cell leukemia 1 | 17
acute quadriplegic myopathy 1 | 1,158
adrenocortical adenoma 1 | 131
aldosterone-producing adenoma 1 | 665
atypical teratoid/rhabdoid tumor 1 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
facioscapulohumeral dystrophy 1 | 288
limb girdle muscular dystrophy 2A 1 | 213
mucosa-associated lymphoid tissue lymphoma 1 | 484
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,109
progressive supranuclear palsy 1 | 676
spina bifida 1 | 1,074
substance-related disorder 1 | 162

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 6 | 12,091

GO Function

clathrin adaptor activity 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin-interacting protein 1 HIP1 Tbio Non-IDG -1.73638 55.9 202
Disabled homolog 2 DAB2 Tbio Non-IDG -2.26146 184.8 239
Phosphatidylinositol-binding clathrin assembly protein PICALM Tbio Non-IDG -1.92862 84.7 130
Beta-arrestin-1 ARRB1 Tbio Non-IDG -2.63877 418.5 490
Huntingtin-interacting protein 1-related protein HIP1R Tbio Non-IDG -1.52916 38.6 195
Low density lipoprotein receptor adapter protein 1 LDLRAP1 Tbio Non-IDG -2.44381 269.9 357