Development Level

Tbio 30 | 10,625
Tchem 9 | 1,890
Tclin 1 | 602
Tdark 1 | 7,003

IMPC Term

abnormal retinal pigmentation 2 | 61
decreased circulating insulin ... 2 | 75
increased body weight 2 | 42
increased bone mineral density 2 | 52
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal eye size 1 | 11
abnormal hair growth 1 | 8
abnormal nail morphology 1 | 7
abnormal retina morphology 1 | 100
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased memory-marker CD4-ne... 1 | 4
decreased rib number 1 | 59
hyperactivity 1 | 108
hypoactivity 1 | 89
immune system phenotype 1 | 17
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small adrenal glands 1 | 15

Disease

ovarian cancer 24 | 8,484
psoriasis 22 | 6,685
osteosarcoma 21 | 7,933
Atherosclerosis 14 | 275
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
medulloblastoma, large-cell 14 | 6,234
glioblastoma 13 | 5,572
lung cancer 13 | 4,466
malignant mesothelioma 13 | 3,162
pilocytic astrocytoma 13 | 3,086
invasive ductal carcinoma 12 | 2,950
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
diabetes mellitus 10 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
subependymal giant cell astrocytoma 10 | 2,287
Down syndrome 9 | 548
Lipid metabolism disorder 9 | 102
adrenocortical carcinoma 9 | 1,427
interstitial cystitis 9 | 2,299
pancreatic cancer 9 | 2,300
pediatric high grade glioma 9 | 2,712
Coronary artery disease 8 | 240
atypical teratoid / rhabdoid tumor 8 | 4,369
lung carcinoma 8 | 2,844
Metabolic syndrome X 7 | 155
Obesity 7 | 616
astrocytoma 7 | 1,493
atypical teratoid/rhabdoid tumor 7 | 1,095
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
oligodendroglioma 7 | 2,849
tuberculosis 7 | 1,557
ulcerative colitis 7 | 2,087
Alzheimer's disease 6 | 644
Cancer 6 | 2,346
Hypercholesterolemia, Familial 6 | 16
active Crohn's disease 6 | 918
cystic fibrosis 6 | 1,665
ependymoma 6 | 2,514
group 4 medulloblastoma 6 | 1,875
posterior fossa group A ependymoma 6 | 1,511
primitive neuroectodermal tumor 6 | 3,031
Cardiovascular system disease 5 | 194
Neurodegenerative disease 5 | 383
acute quadriplegic myopathy 5 | 1,157
adult high grade glioma 5 | 2,148
astrocytic glioma 5 | 2,241
dermatomyositis 5 | 933
juvenile dermatomyositis 5 | 1,189
lung adenocarcinoma 5 | 2,713
primary pancreatic ductal adenocarcinoma 5 | 1,271
spina bifida 5 | 1,064
Atopic dermatitis 4 | 944
Breast cancer 4 | 3,094
Cerebrovascular disease 4 | 231
Dementia 4 | 129
Duchenne muscular dystrophy 4 | 602
Hypertensive disease 4 | 193
Pick disease 4 | 1,893
Simpson-Golabi-Behmel syndrome 4 | 17
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
nasopharyngeal carcinoma 4 | 1,056
pituitary cancer 4 | 1,972
posterior fossa group B ependymoma 4 | 1,530
progressive supranuclear palsy 4 | 674
sonic hedgehog group medulloblastoma 4 | 1,482
Age related macular degeneration 3 | 84
Amyloidosis 3 | 68
Amyotrophic Lateral Sclerosis 3 | 431
Cardiovascular Diseases 3 | 50
Drug-Induced Liver Injury 3 | 118
Heart disease 3 | 279
Hyperlipidemia 3 | 25
Hyperlipoproteinemias 3 | 6
Hypertension 3 | 287
IGA Glomerulonephritis 3 | 454
Kidney disease 3 | 396
Lung Neoplasms 3 | 171
Peripheral Neuropathy 3 | 303
Toxic encephalopathy 3 | 131
Vascular disease 3 | 281
Weight Gain 3 | 87
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
group 3 medulloblastoma 3 | 2,254
hereditary spastic paraplegia 3 | 313
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
primary Sjogren syndrome 3 | 789
Endometriosis 2 | 535
Hypercholesterolemia 2 | 27
Multiple Sclerosis 2 | 498
Polycystic Ovary Syndrome 2 | 332
Type 2 diabetes mellitus 2 | 189
Waldenstrons macroglobulinemia 2 | 765
fibroadenoma 2 | 557
mucosa-associated lymphoid tissue lymphoma 2 | 480
nephrosclerosis 2 | 329
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 41 | 17,995
Cardiovascular System 41 | 17,958
Digestive Tract 41 | 18,473
Endocrine System 41 | 18,512
Female tissues 41 | 18,647
Liver and Pancreas 41 | 18,136
Nervous System 41 | 18,561
Respiratory system 41 | 17,484
Skin and soft tissues 41 | 18,115
Urinary Tract 41 | 18,444
Male tissues 40 | 17,969

Target Family

Non-IDG 36 | 11,971
Enzyme 2 | 4,146
Transporter 2 | 473
Nuclear Receptor 1 | 48

GO Function

cholesterol binding 41 | 41
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.80284 593.9 352
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.90374 836.7 239
Translocator protein 2 TSPO2 Tdark Non-IDG -0.56163 3.14 1
Steroidogenic acute regulatory protein, mitochondrial STAR Tbio Non-IDG -2.80784 708.8 168
StAR-related lipid transfer protein 6 STARD6 Tbio Non-IDG -1.04597 12.1 53
Oxysterol-binding protein-related protein 5 OSBPL5 Tbio Non-IDG -0.90199 8.33 55
Erlin-2 ERLIN2 Tbio Non-IDG -1.24538 18.7 148
Apolipoprotein F APOF Tbio Non-IDG -1.48899 35.4 199