Development Level

Tbio 6 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

increased circulating iron lev... 1 | 30

Disease

Carcinoma 6 | 11,493
Autosomal recessive predisposition 4 | 1,442
Diastrophic dysplasia 4 | 21
Kidney cancer 4 | 2,613
Pendred Syndrome 4 | 22
psoriasis 4 | 6,694
Diarrhea 3 | 253
Failure to gain weight 3 | 365
Pediatric failure to thrive 3 | 365
cystic fibrosis 3 | 1,696
osteosarcoma 3 | 7,950
ulcerative colitis 3 | 1,819
Abdomen distended 2 | 43
Abnormality of metabolism/homeostasis 2 | 134
Constipation 2 | 181
Endometriosis 2 | 540
Epilepsy 2 | 792
Epilepsy, Temporal Lobe 2 | 23
Icterus 2 | 82
Intestinal Obstruction 2 | 31
Lung disease 2 | 142
Metabolic acidosis 2 | 90
Nephrocalcinosis 2 | 35
Nephrolithiasis 2 | 56
Nonsyndromic deafness 2 | 142
Schizophrenia 2 | 1,160
Seizures 2 | 596
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
Anemia, Hemolytic 1 | 55
Anemia, hereditary spherocytic hemolytic 1 | 5
Aspergillosis 1 | 26
Athyreosis 1 | 4
Athyroidal hypothyroidism 1 | 5
Autosomal dominant polycystic kidney disease 1 | 31
Bartter disease 1 | 13
Biliary cirrhosis 1 | 45
Bronchiectasis 1 | 64
Cardiovascular Abnormalities 1 | 31
Choledochal Cyst 1 | 9
Chronic lung disease 1 | 6
Cochlear malformation 1 | 5
Colitis, Ulcerative 1 | 59
Compensated hypothyroidism 1 | 5
Congenital hypothyroidism 1 | 26
DEAFNESS, AUTOSOMAL RECESSIVE 4, WITH ENLARGED VESTIBULAR AQUEDUCT 1 | 3
Diaphragmatic Hernia 1 | 40
Distal Renal Tubular Acidosis 1 | 3
Distal intestinal obstruction syndrome 1 | 2
Elliptocytosis found 1 | 7
Elliptocytosis, Hereditary 1 | 9
Endolymphatic hydrops 1 | 1
Enlarged vestibular aqueduct 1 | 10
Goiter 1 | 38
Graves' disease 1 | 24
HYPOTHYROIDISM, CONGENITAL, DUE TO THYROID DYSGENESIS 1 | 4
Hearing Loss, Sensorineural 1 | 11
Hereditary pancreatitis 1 | 6
Hernia, Diaphragmatic 1 | 40
Hyperactive renin-angiotensin system 1 | 8
Hypersomnia 1 | 8
Hypochloremia (disorder) 1 | 6
Hyponatremia 1 | 25
Hypoplastic cochlea 1 | 6
Idiopathic bronchiectasis 1 | 4
Increased plasma renin activity 1 | 8
Increased red cell osmotic fragility 1 | 4
Low tension glaucoma 1 | 7
Meconium ileus 1 | 3
Meconium ileus on ultrasonography 1 | 2
Metabolic alkalosis 1 | 4
Non-obstructive azoospermia 1 | 21
Pancreatic Insufficiency 1 | 13
Pancreatitis, Chronic 1 | 9
Pancreatitis, Hereditary 1 | 6
Pendred's syndrome 1 | 3
Polycystic Kidney, Autosomal Recessive 1 | 9
Postnatal growth retardation 1 | 57
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE 1 | 3
Recurrent bronchopulmonary infections 1 | 2
Reticulocytosis 1 | 20
Serum chloride level decreased (finding) 1 | 6
Sinusitis 1 | 65
Spherocytosis 1 | 5
Stomatocytosis Result 1 | 6
Thyroid Agenesis 1 | 5
Thyroid Hypoplasia 1 | 4
Thyroid carcinoma 1 | 5
Vestibular dysfunction 1 | 7
Vulvar leiomyoma 1 | 3
autosomal recessive nonsyndromic deafness 4 1 | 6
periodic paralysis (finding) 1 | 3

Tissue

Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 6 | 15,192

Target Family

Transporter 5 | 473
Ion Channel 3 | 344

GO Function

chloride transmembrane transpo... 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cystic fibrosis transmembrane conductance regulator CFTR Tclin Ion Channel -3.79415 6397.4 472
Solute carrier family 12 member 5 SLC12A5 Tbio Transporter -2.58623 402.8 217
Chloride anion exchanger SLC26A3 Tbio Transporter -2.83731 669.8 49
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.90119 75.2 94
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.23613 1628.1 165
Pendrin SLC26A4 Tbio Transporter -2.69164 501.3 100
Sulfate anion transporter 1 SLC26A1 Tbio Ion Channel -1.30769 18.8 77
Excitatory amino acid transporter 3 SLC1A1 Tchem Transporter -2.59660 395.6 251