Development Level

Tbio 5 | 10,625
Tchem 1 | 1,890
Tclin 1 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

Disease

Diastrophic dysplasia 4 | 21
psoriasis 4 | 6,685
Carcinoma 3 | 2,147
Diarrhea 3 | 155
cystic fibrosis 3 | 1,670
osteosarcoma 3 | 7,933
ulcerative colitis 3 | 2,087
Lung disease 2 | 136
Metabolic acidosis 2 | 49
Nephrolithiasis 2 | 31
astrocytoma 2 | 1,493
ependymoma 2 | 2,514
glioblastoma 2 | 5,572
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung adenocarcinoma 2 | 2,714
lung cancer 2 | 4,473
medulloblastoma, large-cell 2 | 6,234
non-small cell lung cancer 2 | 2,798
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
primitive neuroectodermal tumor 2 | 3,031
Acute urate nephropathy 1 | 6
Anemia 1 | 252
Anemia, Hemolytic 1 | 12
Anemia, hereditary spherocytic hemolytic 1 | 5
Aspergillosis 1 | 23
Athyreosis 1 | 4
Autistic Disorder 1 | 320
Azoospermia 1 | 89
BLOOD GROUP--FROESE 1 | 1
BLOOD GROUP--WALDNER TYPE 1 | 1
BLOOD GROUP--WRIGHT ANTIGEN 1 | 1
Bartter Disease 1 | 12
Bronchiectasis 1 | 29
Bronchiectasis with or without elevated sweat chloride 1 1 | 2
Bronchitis 1 | 44
Calcinosis 1 | 63
Central sleep apnea 1 | 12
Cholera 1 | 33
Colorectal Neoplasms 1 | 217
Common cold 1 | 63
Congenital hemolytic anemia 1 | 31
Cryohydrocytosis 1 | 1
DEAFNESS, AUTOSOMAL RECESSIVE 4, WITH ENLARGED VESTIBULAR AQUEDUCT 1 | 2
Deafness, autosomal recessive, 4 1 | 1
Diaphragmatic Hernia 1 | 40
Diphtheria 1 | 23
Distal Renal Tubular Acidosis 1 | 1
Elliptocytosis, Hereditary 1 | 5
Endolymphatic hydrops 1 | 3
Enlarged vestibular aqueduct 1 | 10
Epilepsy, Temporal Lobe 1 | 23
Exocrine pancreatic insufficiency 1 | 21
Goiter 1 | 27
Graves' disease 1 | 25
HE, STOMATOCYTIC 1 | 1
Hematological Disease 1 | 8
Hemochromatosis type 1 1 | 9
Hemolytic anemia 1 | 70
Hereditary elliptocytosis 1 | 20
Hereditary pancreatitis 1 | 4
Hereditary spherocytosis 1 | 20
Hodgkin's lymphoma, nodular sclerosis 1 | 24
Hyperalgesia 1 | 71
Hypokalemia 1 | 40
Idiopathic bronchiectasis 1 | 4
Infertility 1 | 163
Intestinal obstruction 1 | 16
MALARIA, CEREBRAL, RESISTANCE TO 1 | 2
Male infertility with azoospermia or oligozoospermia due to single gene mutation 1 | 9
Nonsyndromic deafness 1 | 121
Obstructive sleep apnea 1 | 28
Ovalocytosis, Hereditary Hemolytic 1 | 1
Ovalocytosis, Southeast Asian 1 | 1
Pancreatitis 1 | 97
Pancreatitis, Chronic 1 | 7
Pancreatitis, hereditary 1 | 6
Pendred syndrome 1 | 1
Pendred's syndrome 1 | 3
Polycystic kidney disease 1 | 54
Polyhydramnios 1 | 29
Pseudohyperkalemia Cardiff 1 | 1
RENAL TUBULAR ACIDOSIS, DISTAL, WITH HEMOLYTIC ANEMIA (disorder) 1 | 1
Renal tubular acidosis 1 | 14
Renal tubular acidosis, distal, autosomal dominant 1 | 1
Renal tubular acidosis, distal, autosomal recessive 1 | 2
Renal tubular acidosis, distal, with hemolytic anemia 1 | 1
Renal tubular acidosis, distal, with normal red cell morphology 1 | 1
Rhinitis 1 | 46
Sensorineural Hearing Loss (disorder) 1 | 11
Sensorineural hearing loss 1 | 107
Sinusitis 1 | 30
Spherocytosis 4 1 | 1
Steatorrhea 1 | 20
Substance-Related Disorders 1 | 114
Thyroid Hypoplasia 1 | 3
Tourette Syndrome 1 | 3
autosomal recessive nonsyndromic deafness 4 1 | 3
cystic fibrosis and chronic rhinosinusitis 1 | 213
head and neck cancer and chronic obstructive pulmonary disease 1 | 237

Tissue

Blood and immune system 7 | 17,995
Cardiovascular System 7 | 17,958
Digestive Tract 7 | 18,473
Endocrine System 7 | 18,512
Female tissues 7 | 18,647
Liver and Pancreas 7 | 18,136
Male tissues 7 | 17,969
Nervous System 7 | 18,561
Respiratory system 7 | 17,484
Skin and soft tissues 7 | 18,115
Urinary Tract 7 | 18,444

Target Family

Transporter 4 | 473
Ion Channel 3 | 341

GO Function

chloride transmembrane transpo... 7 | 7
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.85864 67.8 85
Pendrin SLC26A4 Tbio Transporter -2.65903 426.8 96
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.11115 1271.7 133
Cystic fibrosis transmembrane conductance regulator CFTR Tclin Ion Channel -3.77283 5988.4 267
Chloride anion exchanger SLC26A3 Tbio Transporter -2.81873 656.2 41
Solute carrier family 12 member 5 SLC12A5 Tchem Transporter -2.54604 352.6 176
Sulfate anion transporter 1 SLC26A1 Tbio Ion Channel -1.29595 19.3 72