Development Level

Tbio 3 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
preweaning lethality, complete... 1 | 979
prolonged ST segment 1 | 36

Disease

Carcinoma 6 | 11,493
medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
Cancer 4 | 2,499
Alcoholic Intoxication, Chronic 3 | 289
diabetes mellitus 3 | 1,728
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Hypertension 2 | 396
Hypertensive disorder 2 | 56
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Stomach Neoplasms 2 | 300
Waldenstrons macroglobulinemia 2 | 765
Weight Gain 2 | 100
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,398
type II diabetes mellitus and post-ischemic heart failure 2 | 88
Acro-Osteolysis 1 | 12
Acrocallosal syndrome 1 | 12
Agenesis of teeth 1 | 21
Aggressive Periodontitis 1 | 12
Albuminuria 1 | 21
Arrhythmias, Cardiac 1 | 19
Articular gout 1 | 11
Atrophy of alveolar ridges 1 | 1
Atypical autism 1 | 26
Autosomal dominant polycystic kidney disease 1 | 31
Berylliosis 1 | 28
Blastic phase chronic myeloid leukemia 1 | 58
Bone Marrow Diseases 1 | 7
C1 inhibitor deficiency 1 | 8
Calcified choroid plexus 1 | 2
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Chronic furunculosis 1 | 2
Chronic phase chronic myeloid leukemia 1 | 45
Congenital palmoplantar keratosis 1 | 1
Cycloplegia 1 | 12
Dermatofibrosarcoma protuberans 1 | 15
Diabetic retinopathy 1 | 56
Drug Hypersensitivity 1 | 34
Exanthem 1 | 37
Extrahepatic cholestasis 1 | 2
Flattening of alveolar margin 1 | 1
Flattening of alveolar processes of jaw 1 | 1
Gastrointestinal stromal tumor 1 | 62
Gingivitis 1 | 29
HAIM-MUNK SYNDROME 1 | 1
Keratosis palmoplantaris with periodontopathia and onychogryposis 1 | 1
Kidney Failure, Chronic 1 | 46
Memory Disorders 1 | 40
Meningococcal Infections 1 | 4
Miles-Carpenter syndrome 1 | 4
Myocardial Infarction Prevention 1 | 7
Papillon-Lefevre Syndrome 1 | 1
Periodontitis, Aggressive, 1 1 | 1
Periodontitis, Juvenile 1 | 1
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 1 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 1 | 47
Pimples 1 | 10
Plague 1 | 19
Pleural empyema 1 | 12
Potter's facies 1 | 10
Recurrent bacterial skin infections 1 | 8
Recurrent cutaneous abscess formation 1 | 4
Reduced number of teeth 1 | 21
Severe periodontitis 1 | 1
Skin Abnormalities 1 | 37
Staphylococcal Infections 1 | 5
Substance abuse 1 | 59
Superficial Ocular Infection 1 | 6
Tapering pointed ends of distal finger phalanges 1 | 3
Toxic diffuse goiter 1 | 2
Urinary tract obstruction 1 | 11
pustule 1 | 10

Tissue

Digestive Tract 9 | 17,369
Nervous System 9 | 16,725
Cardiovascular System 8 | 15,192
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Respiratory system 8 | 16,393
Blood and immune system 7 | 16,909
Liver and Pancreas 7 | 16,750
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 2 | 12,091
Transporter 1 | 473

GO Function

chloride ion binding 9 | 9
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
G/T mismatch-specific thymine DNA glycosylase TDG Tbio Enzyme -2.46252 297.6 225
Angiotensin-converting enzyme ACE Tclin Enzyme -4.52754 30363.8 643
Neuroligin-4, X-linked NLGN4X Tbio Enzyme -1.77739 57.8 135
Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 Tchem Enzyme -1.92807 86.0 320
Pancreatic alpha-amylase AMY2A Tclin Enzyme -2.93089 824.2 250
Solute carrier family 22 member 6 SLC22A6 Tclin Transporter -2.32617 211.2 200
Atrial natriuretic peptide receptor 3 NPR3 Tchem Non-IDG -2.25697 195.6 264
Lipocalin-1 LCN1 Tbio Non-IDG -2.34933 221.3 172