Development Level

Tbio 29 | 10,625
Tclin 12 | 602
Tchem 8 | 1,890
Tdark 4 | 7,003

Collection

Eligible Ion Channel Proteins 19 | 117

IMPC Term

abnormal heart morphology 1 | 51
abnormal testis morphology 1 | 30
enlarged heart 1 | 111
improved glucose tolerance 1 | 56
small testis 1 | 37

Disease

psoriasis 23 | 6,685
osteosarcoma 21 | 7,933
medulloblastoma, large-cell 20 | 6,234
ovarian cancer 19 | 8,484
atypical teratoid / rhabdoid tumor 17 | 4,369
glioblastoma 15 | 5,572
cystic fibrosis 14 | 1,665
oligodendroglioma 14 | 2,849
malignant mesothelioma 13 | 3,162
pilocytic astrocytoma 13 | 3,086
primitive neuroectodermal tumor 13 | 3,031
Carcinoma 12 | 2,147
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
lung cancer 12 | 4,466
lung carcinoma 12 | 2,844
pancreatic cancer 12 | 2,300
Epilepsy 11 | 346
Anxiety 10 | 24
Breast cancer 10 | 3,094
General anesthesia 10 | 53
Insomnia 10 | 20
Tonic-clonic epilepsy 10 | 47
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
medulloblastoma 10 | 1,524
pediatric high grade glioma 10 | 2,712
ulcerative colitis 10 | 2,087
Diastrophic dysplasia 9 | 21
Sedation as Adjunct to Anesthesia 9 | 15
ependymoma 9 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
lung adenocarcinoma 9 | 2,713
non-small cell lung cancer 9 | 2,798
Pick disease 8 | 1,893
Schizophrenia 8 | 501
astrocytic glioma 7 | 2,241
colon cancer 7 | 1,475
interstitial cystitis 7 | 2,299
subependymal giant cell astrocytoma 7 | 2,287
Nephrolithiasis 6 | 30
active Crohn's disease 6 | 918
astrocytoma 6 | 1,493
esophageal adenocarcinoma 6 | 737
posterior fossa group A ependymoma 6 | 1,511
Alcohol dependence 5 | 107
Alcohol withdrawal delirium 5 | 9
Alcohol withdrawal syndrome 5 | 9
Autistic Disorder 5 | 320
Benzodiazepine Induced Sedation 5 | 8
Benzodiazepine Maintained Anesthesia 5 | 8
Benzodiazepine Toxicity 5 | 8
Conscious sedation 5 | 10
Feeling agitated 5 | 7
Induce Anterograde Amnesia 5 | 9
Local anesthesia 5 | 40
Panic disorder 5 | 55
Preoperative Anxiety 5 | 9
Sedation 5 | 11
Sedation in Intubated Patients 5 | 8
Spasticity 5 | 26
Status Epilepticus 5 | 85
Tetanus 5 | 66
adult high grade glioma 5 | 2,148
nasopharyngeal carcinoma 5 | 1,056
non primary Sjogren syndrome sicca 5 | 840
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,271
tuberculosis and treatment for 6 months 5 | 686
Anxiety associated with Menopause 4 | 7
BESTROPHINOPATHY 4 | 4
Dent disease 4 | 20
Diarrhea 4 | 155
Down syndrome 4 | 548
Generalized anxiety disorder 4 | 29
Intellectual disability 4 | 573
Irritable bowel syndrome 4 | 59
Mixed anxiety and depressive disorder 4 | 10
Multiple myeloma 4 | 1,327
Nonsyndromic deafness 4 | 121
Osteopetrosis 4 | 40
Partial Epilepsy Treatment Adjunct 4 | 16
Peptic ulcer 4 | 22
Pre-Op Apprehension 4 | 10
Severe Insomnia 4 | 7
Severe anxiety (panic) 4 | 7
Vitelliform macular dystrophy 4 | 14
adrenocortical carcinoma 4 | 1,427
atypical teratoid/rhabdoid tumor 4 | 1,095
cutaneous lupus erythematosus 4 | 1,056
diabetes mellitus 4 | 1,663
ductal carcinoma in situ 4 | 1,745
group 4 medulloblastoma 4 | 1,875
hepatocellular carcinoma 4 | 532
invasive ductal carcinoma 4 | 2,950
pancreatic carcinoma 4 | 567
Duchenne muscular dystrophy 3 | 602
acute myeloid leukemia 3 | 780
aldosterone-producing adenoma 3 | 664
juvenile dermatomyositis 3 | 1,189
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064

Tissue

Female tissues 52 | 18,647
Digestive Tract 51 | 18,473
Endocrine System 51 | 18,512
Nervous System 51 | 18,561
Skin and soft tissues 51 | 18,115
Urinary Tract 51 | 18,444
Blood and immune system 50 | 17,995
Cardiovascular System 50 | 17,958
Male tissues 50 | 17,969
Liver and Pancreas 49 | 18,136
Respiratory system 49 | 17,484

Target Family

Ion Channel 41 | 341
Transporter 10 | 473
Non-IDG 2 | 11,971

GO Function

chloride channel activity 53 | 53
metal ion binding 1,917 | 1,917
ATP binding 1,467 | 1,467
DNA binding 1,432 | 1,432
zinc ion binding 1,155 | 1,155
poly(A) RNA binding 1,107 | 1,107
transcription factor activity,... 853 | 853
calcium ion binding 695 | 695
G-protein coupled receptor act... 661 | 661
protein homodimerization activ... 569 | 569
RNA binding 445 | 445
olfactory receptor activity 424 | 424
sequence-specific DNA binding 398 | 398
GTP binding 374 | 374
chromatin binding 372 | 372
protein serine/threonine kinas... 336 | 336
RNA polymerase II core promote... 332 | 332
identical protein binding 311 | 311
nucleotide binding 311 | 311
receptor binding 303 | 303
protein kinase binding 289 | 289
enzyme binding 286 | 286
cadherin binding involved in c... 277 | 277
GTPase activator activity 273 | 273
ubiquitin protein ligase bindi... 258 | 258
ubiquitin-protein transferase ... 253 | 253
serine-type endopeptidase acti... 246 | 246
transcription coactivator acti... 241 | 241
transcription factor binding 240 | 240
structural molecule activity 232 | 232
GTPase activity 231 | 231
transcriptional activator acti... 230 | 230
ligase activity 227 | 227
protein heterodimerization act... 227 | 227
structural constituent of ribo... 212 | 212
transcription regulatory regio... 202 | 202
transmembrane signaling recept... 201 | 201
RNA polymerase II regulatory r... 200 | 200
receptor activity 200 | 200
transcription corepressor acti... 198 | 198
magnesium ion binding 197 | 197
signal transducer activity 196 | 196
nucleic acid binding 184 | 184
protein kinase activity 183 | 183
carbohydrate binding 180 | 180
ubiquitin protein ligase activ... 173 | 173
RNA polymerase II transcriptio... 162 | 162
heparin binding 160 | 160
iron ion binding 141 | 141
lipid binding 136 | 136
transporter activity 136 | 136
actin binding 133 | 133
ATPase activity 132 | 132
protein C-terminus binding 129 | 129
heme binding 127 | 127
microtubule binding 123 | 123
protein tyrosine kinase activi... 119 | 119
cytokine activity 118 | 118
Ras guanyl-nucleotide exchange... 113 | 113
mRNA binding 112 | 112
metalloendopeptidase activity 112 | 112
transcriptional repressor acti... 110 | 110
structural constituent of cyto... 108 | 108
Rab GTPase binding 105 | 105
antigen binding 104 | 104
protein domain specific bindin... 102 | 102
peptide antigen binding 101 | 101
guanyl-nucleotide exchange fac... 98 | 98
protein complex binding 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 92 | 92
oxidoreductase activity 91 | 91
transcriptional activator acti... 91 | 91
actin filament binding 89 | 89
hydrolase activity 89 | 89
ion channel binding 89 | 89
protein tyrosine phosphatase a... 88 | 88
electron carrier activity 87 | 87
protease binding 87 | 87
histone binding 86 | 86
integrin binding 83 | 83
growth factor activity 82 | 82
phospholipid binding 82 | 82
single-stranded DNA binding 81 | 81
unfolded protein binding 77 | 77
kinase activity 75 | 75
thiol-dependent ubiquitin-spec... 75 | 75
phosphatidylinositol binding 74 | 74
calmodulin binding 73 | 73
histone deacetylase binding 73 | 73
Rho guanyl-nucleotide exchange... 72 | 72
drug binding 71 | 71
double-stranded DNA binding 70 | 70
peptidase activity 70 | 70
protein N-terminus binding 70 | 70
virus receptor activity 68 | 68
beta-catenin binding 67 | 67
microtubule motor activity 67 | 67
protein transporter activity 67 | 67
calcium channel activity 66 | 66
ubiquitin binding 66 | 66

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Solute carrier family 26 member 9 SLC26A9 Tbio Transporter -1.20448 19.3 27
H(+)/Cl(-) exchange transporter 7 CLCN7 Tbio Ion Channel -1.91579 94.4 137
H(+)/Cl(-) exchange transporter 4 CLCN4 Tbio Ion Channel -1.48227 31.6 116
H(+)/Cl(-) exchange transporter 5 CLCN5 Tbio Ion Channel -2.29453 217.9 141
Sulfate transporter SLC26A2 Tbio Transporter -2.43817 275.5 68
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
H(+)/Cl(-) exchange transporter 3 CLCN3 Tchem Ion Channel -2.24361 194.9 155
Anoctamin-1 ANO1 Tclin Ion Channel -2.48376 362.3 422