Development Level

Tchem 12 | 1,598
Tbio 3 | 11,445
Tclin 2 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased heart rate 1 | 18
prolonged RR interval 1 | 8

Disease

Carcinoma 13 | 11,493
psoriasis 8 | 6,694
lung carcinoma 7 | 2,843
Asthma 6 | 385
Cancer 6 | 2,499
cutaneous lupus erythematosus 6 | 1,057
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
Hypersensitivity 5 | 63
Multiple Sclerosis 5 | 540
Pneumonia 5 | 174
Rheumatoid arthritis 5 | 1,191
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
osteosarcoma 5 | 7,950
tuberculosis 5 | 2,010
Acquired immunodeficiency syndrome 4 | 197
Astrocytoma, Pilocytic 4 | 3,081
Celiac disease 4 | 116
Human immunodeficiency virus infectious disease 4 | 138
Inflammatory bowel disease 4 | 151
Status Epilepticus 4 | 98
adult high grade glioma 4 | 3,801
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
medulloblastoma, large-cell 4 | 6,241
ulcerative colitis 4 | 1,819
Arthritis 3 | 290
Atherosclerosis 3 | 291
Dermatitis, Atopic 3 | 37
HIV Infections 3 | 102
Hypersensitivity reaction type II disease 3 | 253
Liver disease 3 | 237
Lung disease 3 | 142
Pulmonary Fibrosis 3 | 106
glioblastoma 3 | 5,792
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
invasive ductal carcinoma 3 | 2,951
mucosa-associated lymphoid tissue lymphoma 3 | 484
non-small cell lung cancer 3 | 2,890
primary Sjogren syndrome 3 | 735
sarcoidosis 3 | 370
Age related macular degeneration 2 | 72
Arthralgia 2 | 90
Autoimmune Diseases 2 | 67
Colitis, Ulcerative 2 | 59
Contact Dermatitis 2 | 81
Dermatitis 2 | 157
Dermatitis, Contact 2 | 71
Encephalitis 2 | 64
Hepatitis C 2 | 94
Human immunodeficiency virus type 1, susceptibility to 2 | 26
Kidney disease 2 | 430
Liver diseases 2 | 87
Malaria 2 | 160
Molluscum contagiosum 2 | 8
Nausea and vomiting 2 | 97
Obesity 2 | 678
Primary sclerosing cholangitis 2 | 14
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
group 3 medulloblastoma 2 | 4,104
head and neck cancer 2 | 271
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
Acne 1 | 52
Actinic keratosis 1 | 21
Acute cystitis 1 | 35
Alopecia areata 1 | 41
Chloracne 1 | 32
Confusion 1 | 21
Dyspareunia 1 | 12
Eosinophilic esophagitis 1 | 16
Glomerulonephritis 1 | 46
Hemiparesis 1 | 34
Histoplasmosis 1 | 13
Infiltrate of lung 1 | 17
Ischemia 1 | 28
Kaposi's sarcoma 1 | 22
Lytic lesion 1 | 32
Nephritis 1 | 51
Pain 1 | 103
Plague 1 | 19
Progressive multifocal leukoencephalopathy 1 | 25
Pyelonephritis 1 | 13
Respiratory Hypersensitivity 1 | 19
Rotting teeth 1 | 73
Sezary Syndrome 1 | 27
Skin Ulcer 1 | 48
Smallpox 1 | 19
Type 1 diabetes mellitus 1 | 109
West Nile fever 1 | 7
chronic kidney disease 1 | 90
hypopigmented skin patch 1 | 59
tick-borne encephalitis 1 | 14

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Nervous System 16 | 16,725
Cardiovascular System 14 | 15,192

Target Family

GPCR 17 | 408

GO Function

chemokine receptor activity 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
Chemokine XC receptor 1 XCR1 Tbio GPCR -1.80855 55.7 206
C-X-C chemokine receptor type 3 CXCR3 Tchem GPCR -2.92733 849.1 650
C-C chemokine receptor type 9 CCR9 Tchem GPCR -2.06247 109.9 394
Atypical chemokine receptor 4 ACKR4 Tbio GPCR -1.64581 46.0 143
Uracil nucleotide/cysteinyl leukotriene receptor GPR17 Tchem GPCR -2.19520 156.1 280
Chemokine-like receptor 1 CMKLR1 Tchem GPCR -2.23881 164.2 383
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.06548 1112.4 530
C-C chemokine receptor type 4 CCR4 Tclin GPCR -2.03230 71.2 486
C-C chemokine receptor type 3 CCR3 Tchem GPCR -2.62143 397.9 554