Development Level

Tbio 20 | 11,445
Tchem 8 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 2 | 278
impaired pupillary reflex 2 | 26
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
cataract 1 | 92
corneal opacity 1 | 32
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
fused cornea and lens 1 | 5
hydrometra 1 | 53
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
limb grasping 1 | 41
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Cancer 19 | 2,499
malignant mesothelioma 14 | 3,232
ovarian cancer 14 | 8,520
psoriasis 14 | 6,694
Breast cancer 13 | 3,578
lung cancer 12 | 4,740
Carcinoma 11 | 11,493
invasive ductal carcinoma 11 | 2,951
lung carcinoma 10 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Atherosclerosis 8 | 291
Liver Cirrhosis, Experimental 8 | 769
Pulmonary Fibrosis 8 | 106
diabetes mellitus 8 | 1,728
lung adenocarcinoma 8 | 2,716
medulloblastoma, large-cell 8 | 6,241
Alzheimer's disease 7 | 658
Breast Neoplasms 7 | 445
Kidney disease 7 | 430
Lung disease 7 | 142
Mammary Neoplasms 7 | 425
cystic fibrosis 7 | 1,696
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
osteosarcoma 7 | 7,950
Arthritis 6 | 290
Depressive disorder 6 | 409
Hypersensitivity reaction type II disease 6 | 253
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
atypical teratoid / rhabdoid tumor 6 | 5,112
colon cancer 6 | 1,478
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
non-small cell lung cancer 6 | 2,890
Carcinoma, Hepatocellular 5 | 228
Cleft Lip 5 | 141
Cleft Palate 5 | 271
Coronary artery disease 5 | 268
Endometriosis 5 | 540
Inflammation 5 | 120
Liver carcinoma 5 | 240
Mesothelioma, Malignant 5 | 105
Myocardial Ischemia 5 | 169
Prostatic Neoplasms 5 | 495
Reperfusion Injury 5 | 86
ductal carcinoma in situ 5 | 1,745
fibroadenoma 5 | 559
interstitial cystitis 5 | 2,312
mucosa-associated lymphoid tissue lymphoma 5 | 484
pancreatic cancer 5 | 2,398
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Amyloidosis 4 | 67
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Gastrointestinal system disease 4 | 54
Keratitis 4 | 62
Liver Cirrhosis 4 | 181
Melanoma 4 | 711
Neoplasm Metastasis 4 | 168
Osteoporosis 4 | 363
Vascular disease 4 | 319
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
limb girdle muscular dystrophy 2A 4 | 213
non primary Sjogren syndrome sicca 4 | 891
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Adenoma 3 | 167
Arthritis, Rheumatoid 3 | 174
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Cerebrovascular disease 3 | 238
Heart disease 3 | 306
Malaria 3 | 160
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Polycystic ovary syndrome 3 | 360
Proliferative vitreoretinopathy 3 | 17
Seizures 3 | 596
Status Epilepticus 3 | 98
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Digestive Tract 30 | 17,369
Male tissues 30 | 17,142
Blood and immune system 29 | 16,909
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Nervous System 28 | 16,725
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400

GO Function

chemoattractant activity 30 | 30
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane glycoprotein NMB GPNMB Tbio Non-IDG -2.05817 130.8 293
Beta-defensin 104 DEFB104B Tbio Non-IDG -1.60840 38.0 35
Secretogranin-2 SCG2 Tbio Non-IDG -2.37107 283.4 175
Nucleic acid dioxygenase ALKBH1 ALKBH1 Tbio Enzyme -2.09946 119.6 149
Serum amyloid A-1 protein SAA1 Tbio Non-IDG -3.09466 1265.8 371
C-C motif chemokine 16 CCL16 Tbio Non-IDG -2.43196 263.6 267
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607
High mobility group protein B2 HMGB2 Tbio Transcription Factor -1.52510 34.5 267
Serum amyloid A-2 protein SAA2 Tbio Non-IDG -1.53680 32.0 35
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667