Development Level

Tbio 67 | 11,445
Tchem 15 | 1,598
Tdark 5 | 6,588
Tclin 4 | 613

IMPC Phenotype

preweaning lethality, incomple... 8 | 499
preweaning lethality, complete... 6 | 979
decreased total body fat amoun... 3 | 207
decreased circulating fructosa... 2 | 30
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
absent vibrissae 1 | 12
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired righting response 1 | 26
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
long tibia 1 | 25
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

ovarian cancer 58 | 8,520
Carcinoma 53 | 11,493
psoriasis 49 | 6,694
osteosarcoma 40 | 7,950
glioblastoma 37 | 5,792
medulloblastoma, large-cell 37 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
ependymoma 30 | 4,679
lung cancer 30 | 4,740
Cancer 27 | 2,499
Breast cancer 24 | 3,578
adult high grade glioma 24 | 3,801
group 3 medulloblastoma 21 | 4,104
malignant mesothelioma 21 | 3,232
diabetes mellitus 19 | 1,728
subependymal giant cell astrocytoma 19 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
invasive ductal carcinoma 18 | 2,951
lung adenocarcinoma 18 | 2,716
pancreatic cancer 18 | 2,398
tuberculosis 18 | 2,010
Autosomal recessive predisposition 17 | 1,442
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
non-small cell lung cancer 17 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Pick disease 16 | 1,894
astrocytic glioma 16 | 2,597
breast carcinoma 15 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
juvenile dermatomyositis 15 | 1,187
oligodendroglioma 15 | 2,850
Astrocytoma, Pilocytic 14 | 3,081
primitive neuroectodermal tumor 14 | 3,035
Neurodegenerative disease 13 | 414
colon cancer 13 | 1,478
acute quadriplegic myopathy 12 | 1,158
ductal carcinoma in situ 12 | 1,745
lung carcinoma 12 | 2,843
ulcerative colitis 12 | 1,819
Alzheimer's disease 11 | 658
Kidney cancer 11 | 2,613
Melanoma 11 | 711
Multiple myeloma 11 | 1,332
Prostatic Neoplasms 11 | 495
interstitial cystitis 11 | 2,312
pituitary cancer 11 | 1,972
Parkinson's disease 10 | 392
astrocytoma 10 | 1,146
group 4 medulloblastoma 10 | 1,855
nasopharyngeal carcinoma 10 | 1,058
Bipolar Disorder 9 | 666
Breast Neoplasms 9 | 445
Cognitive delay 9 | 608
Epilepsy 9 | 792
Global developmental delay 9 | 608
Hypertensive disease 9 | 292
Intellectual disability 9 | 1,016
Mammary Neoplasms 9 | 425
Mental and motor retardation 9 | 608
Schizophrenia 9 | 1,160
active Crohn's disease 9 | 922
adrenocortical carcinoma 9 | 1,428
cystic fibrosis 9 | 1,696
dermatomyositis 9 | 966
Anemia 8 | 365
Atopic dermatitis 8 | 952
Carcinoma, Hepatocellular 8 | 228
Colonic Neoplasms 8 | 142
Dull intelligence 8 | 645
Hypertension 8 | 396
Kidney disease 8 | 430
Liver carcinoma 8 | 240
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Rheumatoid arthritis 8 | 1,191
Seizures 8 | 596
primary pancreatic ductal adenocarcinoma 8 | 1,109
spina bifida 8 | 1,074
Atherosclerosis 7 | 291
Chemical and Drug Induced Liver Injury 7 | 195
Depressive disorder 7 | 409
Duchenne muscular dystrophy 7 | 601
Stomach Neoplasms 7 | 300
Toxic encephalopathy 7 | 141
gastric carcinoma 7 | 807
Cerebellar Ataxia 6 | 304
Coronary artery disease 6 | 268
Dementia 6 | 175
Lung Neoplasms 6 | 232
Obesity 6 | 678
Osteoporosis 6 | 363
Parkinson Disease 6 | 64
Polycystic ovary syndrome 6 | 360
Short stature 6 | 531
Thrombocytopenia 6 | 197
Waldenstrons macroglobulinemia 6 | 765
cutaneous lupus erythematosus 6 | 1,057
hereditary spastic paraplegia 6 | 318

Tissue

Endocrine System 90 | 18,159
Digestive Tract 89 | 17,369
Female tissues 88 | 17,400
Liver and Pancreas 88 | 16,750
Male tissues 88 | 17,142
Respiratory system 88 | 16,393
Skin and soft tissues 88 | 17,230
Blood and immune system 87 | 16,909
Nervous System 87 | 16,725
Urinary Tract 87 | 16,678
Cardiovascular System 84 | 15,192

Target Family

Non-IDG 65 | 12,091
Enzyme 18 | 4,145
Transporter 4 | 473
Transcription Factor 3 | 1,400
Kinase 1 | 634

GO Function

chaperone binding 91 | 91
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
DnaJ homolog subfamily A member 4 DNAJA4 Tbio Non-IDG -0.52235 2.67 120
BAG family molecular chaperone regulator 1 BAG1 Tbio Non-IDG -2.50252 335.1 394
Mitochondrial import inner membrane translocase subunit Tim9 TIMM9 Tbio Enzyme -1.31703 21.3 72
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
BAG family molecular chaperone regulator 2 BAG2 Tbio Non-IDG -2.00557 102.4 235
Sacsin SACS Tbio Non-IDG -2.64601 427.1 19
Activator of 90 kDa heat shock protein ATPase homolog 2 AHSA2P Tdark Enzyme -0.05436 1.25 76