Development Level

Tbio 51 | 11,445
Tclin 6 | 613
Tchem 5 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

decreased grip strength 5 | 116
abnormal locomotor behavior 3 | 24
decreased fasted circulating g... 3 | 65
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
preweaning lethality, complete... 3 | 979
tremors 3 | 39
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased circulating HDL chol... 2 | 68
decreased circulating alkaline... 2 | 46
decreased circulating choleste... 2 | 93
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
enlarged stomach 2 | 2
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased red blood cell distr... 2 | 34
short tibia 2 | 97
small thymus 2 | 16
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal tail movements 1 | 12
absent startle reflex 1 | 24
aorta stenosis 1 | 2
decreased body length 1 | 101
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased coping response 1 | 8
decreased food intake 1 | 13
decreased glycosylated hemoglo... 1 | 1
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
dilated heart left ventricle 1 | 11
enlarged liver 1 | 2
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
male infertility 1 | 123
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 52 | 11,493
osteosarcoma 36 | 7,950
ovarian cancer 33 | 8,520
glioblastoma 30 | 5,792
interstitial cystitis 30 | 2,312
lung cancer 27 | 4,740
medulloblastoma, large-cell 26 | 6,241
Cancer 25 | 2,499
Kidney cancer 24 | 2,613
atypical teratoid / rhabdoid tumor 24 | 5,112
psoriasis 24 | 6,694
Breast cancer 23 | 3,578
ependymoma 23 | 4,679
malignant mesothelioma 23 | 3,232
adult high grade glioma 22 | 3,801
invasive ductal carcinoma 20 | 2,951
Astrocytoma, Pilocytic 19 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung carcinoma 19 | 2,843
non-small cell lung cancer 19 | 2,890
lung adenocarcinoma 17 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
pituitary cancer 15 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
Autistic Disorder 14 | 364
group 3 medulloblastoma 14 | 4,104
pancreatic cancer 14 | 2,398
ulcerative colitis 14 | 1,819
cutaneous lupus erythematosus 13 | 1,057
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
primitive neuroectodermal tumor 13 | 3,035
tuberculosis 13 | 2,010
Schizophrenia 12 | 1,160
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
Liver cancer 11 | 604
colon cancer 11 | 1,478
oligodendroglioma 11 | 2,850
breast carcinoma 10 | 1,638
Liver Cirrhosis, Experimental 9 | 769
group 4 medulloblastoma 9 | 1,855
primary Sjogren syndrome 9 | 735
Multiple Sclerosis 8 | 540
astrocytic glioma 8 | 2,597
pediatric high grade glioma 8 | 1,064
Autosomal recessive predisposition 7 | 1,442
Down syndrome 7 | 499
Endometrial cancer 7 | 311
Pick disease 7 | 1,894
dermatomyositis 7 | 966
diabetes mellitus 7 | 1,728
medulloblastoma 7 | 720
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Autism spectrum disorder 6 | 101
Crohn's disease 6 | 321
Melanoma 6 | 711
Obesity 6 | 678
Prostatic Neoplasms 6 | 495
spina bifida 6 | 1,074
Asperger syndrome 5 | 37
Asthma 5 | 385
Atopic dermatitis 5 | 952
Cleft lip-palate-ectodermal dysplasia syndrome 5 | 8
Duchenne muscular dystrophy 5 | 601
Hypersensitivity reaction type II disease 5 | 253
Intellectual disability 5 | 1,016
Kidney disease 5 | 430
Vascular disease 5 | 319
astrocytoma 5 | 1,146
nasopharyngeal carcinoma 5 | 1,058
Alopecia 4 | 115
Amyotrophic lateral sclerosis 4 | 451
Autism Spectrum Disorders 4 | 75
Bipolar Disorder 4 | 666
Cardiomyopathy, Dilated 4 | 83
Chronic Lymphocytic Leukemia 4 | 262
Dilated cardiomyopathy 4 | 56
Endometriosis 4 | 540
Malaria 4 | 160
Nicotine dependence 4 | 54
Pitt-Hopkins syndrome 4 | 20
Rheumatoid arthritis 4 | 1,191
Skin cancer 4 | 469
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
acute quadriplegic myopathy 4 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
juvenile dermatomyositis 4 | 1,187
primary pancreatic ductal adenocarcinoma 4 | 1,109
sonic hedgehog group medulloblastoma 4 | 467
Arthritis 3 | 290
Mental Depression 3 | 333
Myocardial Ischemia 3 | 169
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562

Tissue

Blood and immune system 60 | 16,909
Digestive Tract 60 | 17,369
Liver and Pancreas 60 | 16,750
Urinary Tract 60 | 16,678
Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Male tissues 59 | 17,142
Respiratory system 59 | 16,393
Skin and soft tissues 59 | 17,230
Nervous System 58 | 16,725
Cardiovascular System 53 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 10 | 4,145
GPCR 1 | 408
Transporter 1 | 473

GO Function

cell adhesion molecule binding 63 | 63
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Teneurin-1 TENM1 Tbio Non-IDG -1.81805 61.8 60
Small cell adhesion glycoprotein SMAGP Tdark Non-IDG -0.06695 1.95 82
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Plakophilin-3 PKP3 Tbio Non-IDG -1.37372 26.0 200
Cytotoxic and regulatory T-cell molecule CRTAM Tbio Non-IDG -1.11760 15.6 131
Teneurin-4 TENM4 Tbio Non-IDG -1.41343 23.9 19
Glycophorin-C GYPC Tbio Non-IDG -2.88194 722.9 302