Development Level

Tchem 11 | 1,598
Tdark 5 | 6,588
Tbio 3 | 11,445
Tclin 1 | 613

IMPC Phenotype

abnormal heart morphology 2 | 162
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased monocyte cell number 2 | 63
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal limb bud morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal urinary bladder morph... 1 | 11
decreased circulating alkaline... 1 | 46
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
embryonic growth retardation 1 | 106
enlarged pancreas 1 | 2
increased basophil cell number 1 | 7
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 14 | 11,493
psoriasis 8 | 6,694
cystic fibrosis 7 | 1,696
osteosarcoma 7 | 7,950
atypical teratoid / rhabdoid tumor 6 | 5,112
ovarian cancer 6 | 8,520
Breast cancer 5 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
Dentin sensitivity 4 | 14
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Hypertension 3 | 396
Melanoma 3 | 711
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
ARTHROGRYPOSIS, DISTAL, TYPE 2B 2 | 6
Cancer 2 | 2,499
Distal arthrogryposis 2 | 42
Endometrial cancer 2 | 311
Neurodegenerative disease 2 | 414
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Alcoholism 1 | 45
Arteriosclerotic Parkinsonism 1 | 8
Autosomal dominant nonsyndromic deafness 25 1 | 6
Autosomal dominant polycystic kidney disease 1 | 31
Autosomal recessive nonsyndromic deafness 13 1 | 1
Blastomycosis 1 | 12
Bone Diseases 1 | 8
Bone disease 1 | 10
Brachyolmia Type 3 1 | 1
Cervical Dystonia 1 | 26
Chronic Kidney Diseases 1 | 13
Chronic Obstructive Airway Disease 1 | 37
Congenital hemolytic anemia 1 | 32
Digital Arthropathy-Brachydactyly, Familial 1 | 1
Disturbance in mood 1 | 3
Edema 1 | 81
Episodic ataxia 1 | 22
Extrapyramidal disease 1 | 8
Fascioliasis 1 | 17
Frozen shoulder 1 | 5
Gaucher disease type 3 1 | 67
General anesthesia 1 | 53
Glycoproteinosis 1 | 12
HEREDITARY MOTOR AND SENSORY NEUROPATHY, TYPE IIC (disorder) 1 | 1
Hydrarthrosis 1 | 4
Hypertensive disorder 1 | 56
Hypertrophy 1 | 17
Hypokalemia Prevention 1 | 6
Hyponatremia 1 | 25
Influenza A Prevention 1 | 7
Influenza due to Influenza A virus 1 | 7
Leprosy 1 | 73
Low compliance bladder 1 | 11
Metatrophic dysplasia 1 | 1
Metatropic dwarfism 1 | 1
Nephrotic Syndrome 1 | 78
Neurotoxicity Syndromes 1 | 26
Nonorganic psychosis 1 | 84
Parastremmatic dwarfism 1 | 1
Paronychia 1 | 7
Postencephalitic parkinsonism 1 | 12
Progressive renal failure 1 | 13
Pulmonary Disease, Chronic Obstructive 1 | 31
Reticulocytosis 1 | 20
SODIUM SERUM LEVEL QUANTITATIVE TRAIT LOCUS 1 1 | 1
SPINAL MUSCULAR ATROPHY, DISTAL, CONGENITAL NONPROGRESSIVE (disorder) 1 | 1
SPONDYLOEPIPHYSEAL DYSPLASIA, MAROTEAUX TYPE 1 | 1
Scapuloperoneal Form of Spinal Muscular Atrophy 1 | 1
Scapuloperoneal spinal muscular atrophy 1 | 1
Scoliosis 1 | 44
Splenic infarction 1 | 6
Spondylometaphyseal dysplasia, Kozlowski type 1 | 2
Urination Disorders 1 | 4
Visceral leishmaniasis 1 | 14
X-linked endothelial corneal dystrophy 1 | 9
lingual-facial-buccal dyskinesia 1 | 13

Tissue

Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Digestive Tract 19 | 17,369
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Blood and immune system 18 | 16,909
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Cardiovascular System 17 | 15,192
Liver and Pancreas 17 | 16,750

Target Family

Ion Channel 20 | 344

GO Function

cation channel activity 20 | 20
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Calcium homeostasis modulator protein 3 CALHM3 Tdark Ion Channel -0.10646 0.35 86
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tchem Ion Channel -2.19236 141.8 121
Acid-sensing ion channel 3 ASIC3 Tchem Ion Channel -2.28745 195.8 130
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Piezo-type mechanosensitive ion channel component 2 PIEZO2 Tbio Ion Channel -2.31598 196.2 140
Mucolipin-1 MCOLN1 Tchem Ion Channel -2.43459 272.2 132
Short transient receptor potential channel 1 TRPC1 Tbio Ion Channel -2.52589 340.7 162
Calcium homeostasis modulator protein 4 CALHM4 Tdark Ion Channel 0.00000 4