Development Level

Tbio 20 | 11,445
Tdark 9 | 6,588
Tchem 4 | 1,598

IMPC Phenotype

decreased grip strength 1 | 116
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
increased circulating iron lev... 1 | 30
vertebral fusion 1 | 23

Disease

Carcinoma 20 | 11,493
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 13 | 6,241
psoriasis 12 | 6,694
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung carcinoma 7 | 2,843
Breast cancer 6 | 3,578
Autistic Disorder 5 | 364
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
Asperger syndrome 4 | 37
Astrocytoma, Pilocytic 4 | 3,081
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
medulloblastoma 4 | 720
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Echinococcosis 3 | 26
Liver Cirrhosis, Experimental 3 | 769
Schizophrenia 3 | 1,160
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
non-small cell lung carcinoma 3 | 317
pancreatic cancer 3 | 2,398
primitive neuroectodermal tumor 3 | 3,035
Atopic dermatitis 2 | 952
Atypical autism 2 | 26
Autism spectrum disorder 2 | 101
Cocaine-Related Disorders 2 | 92
Fatty liver disease 2 | 103
Intellectual disability 2 | 1,016
Myocardial Ischemia 2 | 169
Obesity 2 | 678
Steatorrhea 2 | 34
active Crohn's disease 2 | 922
cystic fibrosis 2 | 1,696
group 4 medulloblastoma 2 | 1,855
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
Abdominal Pain 1 | 98
Adverse reaction to drug 1 | 61
Aggressive Periodontitis 1 | 12
Alcoholic Intoxication, Chronic 1 | 289
Alopecia 1 | 115
Autism Spectrum Disorders 1 | 75
Brain Injuries 1 | 65
Cholestasis 1 | 155
Chondrodysplasia punctata 1 | 41
Chondrosarcoma 1 | 21
Degenerative polyarthritis 1 | 115
Diabetes Mellitus, Experimental 1 | 108
Drug-Related Side Effects and Adverse Reactions 1 | 62
Human immunodeficiency virus infectious disease 1 | 138
Hyperopia 1 | 70
Hypotrichosis 1 | 47
Hypotrichosis 13 1 | 2
Hypotrichosis 6 1 | 4
Hypotrichosis 7 1 | 4
Hypotrichosis 8 1 | 6
Hypotrichosis simplex 1 | 7
Hypoxia 1 | 33
Ichthyosis vulgaris 1 | 11
Kabuki syndrome 1 | 27
Liver neoplasms 1 | 130
Lung Neoplasms 1 | 232
Meckel's diverticulum 1 | 5
Melanoma 1 | 711
Monilethrix 1 | 18
Ocular albinism 1 | 26
Osteoarthritis 1 | 184
Pancreatitis 1 | 123
Peeling skin syndrome 1 | 17
Pericarditis 1 | 13
Pruritus 1 | 58
Retinoblastoma 1 | 19
Rickets 1 | 49
Skin cancer 1 | 469
Total Hypotrichosis, Mari type 1 | 1
Wilson disease 1 | 16
Woolly hair, autosomal dominant 1 | 5
Woolly hair, congenital 1 | 5
Wooly hair 1 | 17
X-linked cerebral adrenoleukodystrophy 1 | 116
chronic kidney disease 1 | 90
maturity-onset diabetes of the young 1 | 32
posterior fossa group A ependymoma 1 | 468
posterior fossa group B ependymoma 1 | 416

Tissue

Skin and soft tissues 31 | 17,230
Endocrine System 30 | 18,159
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Digestive Tract 29 | 17,369
Nervous System 29 | 16,725
Urinary Tract 29 | 16,678
Blood and immune system 28 | 16,909
Female tissues 28 | 17,400
Respiratory system 25 | 16,393
Cardiovascular System 23 | 15,192

Target Family

Enzyme 31 | 4,145
Non-IDG 2 | 12,091

GO Function

carboxylic ester hydrolase act... 33 | 33
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative inactive carboxylesterase 4 CES1P1 Tbio Enzyme -2.62475 722.3 0
Acyl-coenzyme A thioesterase 9, mitochondrial ACOT9 Tdark Enzyme -0.13093 1.45 171
Acyl-coenzyme A thioesterase 1 ACOT1 Tdark Enzyme -2.14311 129.6 43
Acyl-coenzyme A thioesterase 4 ACOT4 Tbio Enzyme -0.53787 2.87 58
Arylacetamide deacetylase-like 2 AADACL2 Tdark Enzyme 0.41 0.15 90
Protein ABHD1 ABHD1 Tdark Enzyme -0.22185 2.20 106
Neuroligin-1 NLGN1 Tbio Enzyme -1.96626 95.1 225
Cytosolic acyl coenzyme A thioester hydrolase ACOT7 Tbio Enzyme -2.06780 111.8 102
Lysophospholipase-like protein 1 LYPLAL1 Tbio Enzyme -1.18623 14.4 127
Neuroligin-2 NLGN2 Tbio Enzyme -1.71616 50.4 77