Development Level

Tbio 14 | 11,445
Tchem 9 | 1,598
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased grip strength 2 | 116
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal duodenum morphology 1 | 4
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased pulmonary respirator... 1 | 5
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
enlarged spleen 1 | 41
enlarged stomach 1 | 2
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
microphthalmia 1 | 26
short tibia 1 | 97
small thymus 1 | 16
tremors 1 | 39

Disease

Carcinoma 15 | 11,493
medulloblastoma, large-cell 14 | 6,241
ependymoma 13 | 4,679
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
osteosarcoma 11 | 7,950
group 3 medulloblastoma 10 | 4,104
oligodendroglioma 9 | 2,850
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
astrocytic glioma 7 | 2,597
primitive neuroectodermal tumor 7 | 3,035
Kidney cancer 6 | 2,613
adult high grade glioma 6 | 3,801
colon cancer 6 | 1,478
lung cancer 6 | 4,740
lung carcinoma 6 | 2,843
Alcoholic Intoxication, Chronic 5 | 289
Epilepsy 5 | 792
Major Depressive Disorder 5 | 301
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
subependymal giant cell astrocytoma 5 | 2,287
Autistic Disorder 4 | 364
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Epilepsy, Temporal Lobe 4 | 23
Hypertension 4 | 396
Liver cancer 4 | 604
Mood Disorders 4 | 184
Multiple myeloma 4 | 1,332
Unipolar Depression 4 | 250
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Cardiomegaly 3 | 116
Depressive disorder 3 | 409
Down syndrome 3 | 499
Liver Cirrhosis, Experimental 3 | 769
Melanoma 3 | 711
Mental Depression 3 | 333
Muscle hypotonia 3 | 571
Obesity 3 | 678
Rheumatoid arthritis 3 | 1,191
active ulcerative colitis 3 | 764
adrenocortical carcinoma 3 | 1,428
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
Adult onset 2 | 82
Alcohol dependence 2 | 107
Alzheimer's disease 2 | 658
Amphetamine-Related Disorders 2 | 74
Asthma 2 | 385
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Cardiomyopathy 2 | 116
Cardiovascular Diseases 2 | 59
Chronic Lymphocytic Leukemia 2 | 262
Cocaine Dependence 2 | 51
Cocaine-Related Disorders 2 | 92
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Exercise-induced myalgia 2 | 8
Gout 2 | 106
Heart disease 2 | 306
High forehead 2 | 102
Hypertensive disease 2 | 292
Kidney disease 2 | 430
Myopathy 2 | 185
Pitt-Hopkins syndrome 2 | 20
Seizures 2 | 596
Skin cancer 2 | 469
Substance Withdrawal Syndrome 2 | 55
Substance-Related Disorders 2 | 115
Tall forehead 2 | 102
Toxic encephalopathy 2 | 141
Vascular disease 2 | 319
Ventricular arrhythmia 2 | 27
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010

Tissue

Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Male tissues 24 | 17,142
Blood and immune system 23 | 16,909
Female tissues 23 | 17,400
Skin and soft tissues 23 | 17,230
Nervous System 22 | 16,725
Urinary Tract 22 | 16,678
Liver and Pancreas 21 | 16,750
Respiratory system 21 | 16,393
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 15 | 12,091
Kinase 5 | 634
GPCR 4 | 408

GO Function

calcium channel regulator acti... 24 | 24
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Tetraspanin-13 TSPAN13 Tbio Non-IDG -0.44382 2.87 68
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Hippocalcin-like protein 4 HPCAL4 Tdark Non-IDG -0.58934 3.54 78
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Pro-neuropeptide Y NPY Tbio Non-IDG -3.83401 7433.3 432
Cardiac phospholamban PLN Tbio Non-IDG -1.93701 85.8 365
Neurexin-2 NRXN2 Tbio Non-IDG -0.88939 10.0 42