Development Level

Tchem 7 | 1,598
Tbio 3 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
enlarged lymph nodes 1 | 37
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 11 | 11,493
ovarian cancer 5 | 8,520
Endometriosis 4 | 540
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
Amenorrhea Secondary to Ovarian Dysfunction 3 | 8
Astrocytoma, Pilocytic 3 | 3,081
Atrophic vaginitis 3 | 14
Contraception 3 | 15
Corpus Luteum Insufficiency Syndrome 3 | 8
Dysfunctional uterine bleeding 3 | 9
Endometrial Hyperplasia Prevention 3 | 9
Endometrial carcinoma 3 | 15
Infertility Secondary to Progesterone Deficiency 3 | 8
Menopausal flushing 3 | 17
Postmenopausal osteoporosis 3 | 19
Prevention of Premature Labor 3 | 9
Secondary malignant neoplasm of kidney 3 | 9
Secondary physiologic amenorrhea 3 | 32
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
CATSPER-Related Male Infertility 2 | 3
Infertility 2 | 188
Kidney cancer 2 | 2,613
Male infertility 2 | 206
Spermatogenic Failure 7 2 | 3
active ulcerative colitis 2 | 764
head and neck cancer 2 | 271
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Amphetamine-Related Disorders 1 | 74
Ankylosing spondylitis 1 | 140
Ataxia, Appendicular 1 | 25
Ataxia, Truncal 1 | 21
Atrophy of cerebellum 1 | 103
Autosomal dominant polycystic kidney disease 1 | 31
Autosomal recessive spinocerebellar ataxia 10 1 | 2
Bladder Neoplasm 1 | 112
Bradycardia 1 | 36
Brugada Syndrome (disorder) 1 | 15
Brugada syndrome 1 | 29
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiovascular system disease 1 | 246
Cerebellar Dysmetria 1 | 56
Cerebellar degeneration 1 | 103
Chondroma 1 | 15
Conduction disorder of the heart 1 | 79
Congenital dyserythropoietic anemia 1 | 18
Congenital pes cavus 1 | 88
Deafness, Sensorineural, And Male Infertility 1 | 2
Deafness-Infertility Syndrome 1 | 2
Dentin sensitivity 1 | 14
Dysarthria 1 | 192
EKG abnormalities 1 | 78
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Endometrial cancer 1 | 311
Gait Ataxia 1 | 51
Gastrointestinal stromal tumor 1 | 62
Hereditary ataxia 1 | 2
Hypermetric saccades 1 | 1
Hyperreflexia 1 | 209
Infratentorial atrophy 1 | 103
Leiomyoma 1 | 32
Leiomyosarcoma 1 | 24
Leprosy 1 | 73
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Melanoma 1 | 711
Muscular fasciculation 1 | 22
Neurilemmoma 1 | 23
Neurodegenerative disease 1 | 414
Pain 1 | 103
Paronychia 1 | 7
Polyhydramnios 1 | 108
Prolonged QT interval 1 | 15
Right bundle branch block 1 | 17
SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 10 1 | 1
Sensorineural hearing loss 1 | 106
Skin cancer 1 | 469
Spinocerebellar Ataxias 1 | 34
Spondylitis, Ankylosing 1 | 11
Syncope 1 | 22
Synovial sarcoma 1 | 25
Tracheomalacia 1 | 22
Urinary Bladder Neoplasms 1 | 114
Vertebrobasilar insufficiency 1 | 9
Visceral leishmaniasis 1 | 14
interstitial lung disease 1 | 298
non-small cell lung carcinoma 1 | 317
uncontrolled asthma 1 | 56

Tissue

Endocrine System 12 | 18,159
Digestive Tract 11 | 17,369
Liver and Pancreas 11 | 16,750
Blood and immune system 10 | 16,909
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Nervous System 9 | 16,725
Cardiovascular System 6 | 15,192

Target Family

Ion Channel 11 | 344
Non-IDG 1 | 12,091

GO Function

calcium activated cation chann... 12 | 12
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tchem Ion Channel -2.19236 141.8 121
Anoctamin-10 ANO10 Tbio Non-IDG -1.22069 14.6 54
Transient receptor potential cation channel subfamily M member 5 TRPM5 Tchem Ion Channel -1.98611 95.5 113
Calcium homeostasis modulator protein 1 CALHM1 Tbio Ion Channel -1.71853 53.7 94
Anoctamin-1 ANO1 Tclin Ion Channel -2.58674 414.4 565
Polycystic kidney disease 2-like 1 protein PKD2L1 Tchem Ion Channel -1.95186 96.8 100
Transient receptor potential cation channel subfamily M member 4 TRPM4 Tchem Ion Channel -2.19653 160.9 186
Cation channel sperm-associated protein 1 CATSPER1 Tchem Ion Channel -1.18190 14.0 103
Anoctamin-6 ANO6 Tbio Ion Channel -2.50568 319.2 90
Cation channel sperm-associated protein 4 CATSPER4 Tchem Ion Channel 0.03 0.94 43