Development Level

Tbio 5 | 11,651

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal iris transilluminatio... 1 | 2
abnormal retina morphology 1 | 71
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
enlarged thymus 1 | 5
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
atypical teratoid / rhabdoid tumor 3 | 5,112
osteosarcoma 3 | 7,950
pituitary cancer 3 | 1,972
Kidney cancer 2 | 2,613
Oculocutaneous albinism 2 | 29
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
AMELOGENESIS IMPERFECTA, HYPOMATURATION TYPE, IIA5 1 | 1
Abnormality of macular pigmentation 1 | 16
Achromatopsia 1 | 16
Adenoid Cystic Carcinoma 1 | 99
Amelogenesis Imperfecta hypomaturation type 1 | 7
Amelogenesis Imperfecta, Type III 1 | 3
Amelogenesis imperfecta 1 | 29
Amelogenesis imperfecta, hypocalcification type 1 | 2
Amelogenesis imperfecta, hypomaturation type IIA5 1 | 1
Asthma 1 | 385
Astrocytoma, Pilocytic 1 | 3,081
Atherosclerosis 1 | 291
Autosomal recessive predisposition 1 | 1,442
Brain Ischemia 1 | 110
Breast cancer 1 | 3,578
Carcinoma, Adenoid Cystic 1 | 99
Celiac disease 1 | 116
Chediak-Higashi syndrome 1 | 26
Congenital stationary night blindness 1 | 29
Congenital stationary night blindness 1B 1 | 6
Difficulties with night vision 1 | 87
Hermansky-Pudlak syndrome 1 | 42
Hypoplasia of optic disc 1 | 12
Macular pigmentary changes 1 | 16
Malaria 1 | 160
Multiple Sclerosis 1 | 540
Night Blindness 1 | 101
Night Blindness, Congenital Stationary, Type 1D 1 | 1
Night blindness, congenital stationary 1 | 16
Night blindness, congenital stationary, complete 1 | 10
Night blindness, stationary 1 | 10
Ocular albinism 1 | 26
Oguchi disease 1 | 10
Podoconiosis 1 | 5
Posterior polymorphous corneal dystrophy 1 | 19
Reduced visual acuity 1 | 63
Rosacea 1 | 25
Salivary Gland Neoplasms 1 | 46
Severe myopia 1 | 22
Skin-Hair-Eye Pigmentation, Variation In, 4 1 | 1
active Crohn's disease 1 | 922
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 459
group 4 medulloblastoma 1 | 1,855
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
medulloblastoma 1 | 720
non primary Sjogren syndrome sicca 1 | 891
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
primary pancreatic ductal adenocarcinoma 1 | 1,109
tuberculosis 1 | 2,010

Tissue

Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Blood and immune system 4 | 16,909
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369

Target Family

Transporter 5 | 473

GO Function

calcium, potassium:sodium anti... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.63611 43.9 61
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.32054 20.8 63
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Sodium/potassium/calcium exchanger 1 SLC24A1 Tbio Transporter -1.90810 81.5 92