Development Level

Tbio 16 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal testis morphology 1 | 43
decreased circulating alanine ... 1 | 47
decreased circulating phosphat... 1 | 27
decreased total body fat amoun... 1 | 207
edema 1 | 59
improved glucose tolerance 1 | 79
increased lean body mass 1 | 172
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

ovarian cancer 14 | 8,520
glioblastoma 13 | 5,792
ependymoma 11 | 4,679
medulloblastoma, large-cell 11 | 6,241
Carcinoma 10 | 11,493
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
adult high grade glioma 9 | 3,801
atypical teratoid / rhabdoid tumor 9 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pancreatic cancer 9 | 2,398
Cancer 8 | 2,499
lung adenocarcinoma 8 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
spina bifida 8 | 1,074
Astrocytoma, Pilocytic 7 | 3,081
Breast cancer 7 | 3,578
esophageal adenocarcinoma 6 | 737
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
pituitary cancer 6 | 1,972
Liver Cirrhosis, Experimental 5 | 769
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
subependymal giant cell astrocytoma 5 | 2,287
Animal Mammary Neoplasms 4 | 136
Becker muscular dystrophy 4 | 191
Duchenne muscular dystrophy 4 | 601
Mammary Neoplasms, Animal 4 | 136
Prostatic Neoplasms 4 | 495
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
limb girdle muscular dystrophy 2A 4 | 213
oligodendroglioma 4 | 2,850
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
Chemical and Drug Induced Liver Injury 3 | 195
Down syndrome 3 | 499
Mammary Neoplasms, Experimental 3 | 154
Neoplasm Invasiveness 3 | 161
Rheumatoid arthritis 3 | 1,191
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
group 3 medulloblastoma 3 | 4,104
nasopharyngeal carcinoma 3 | 1,058
Amyotrophic lateral sclerosis 2 | 451
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Carcinoma, Squamous Cell 2 | 110
Hepatitis B 2 | 108
Liver disease 2 | 237
Liver neoplasms 2 | 130
Mouth Neoplasms 2 | 55
Multiple myeloma 2 | 1,332
Pick disease 2 | 1,894
Prostate cancer 2 | 175
Schizophrenia 2 | 1,160
Squamous cell carcinoma 2 | 129
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
chronic kidney disease 2 | 90
chronic lymphosyte leukemia 2 | 204
colon cancer 2 | 1,478
dentatorubral-pallidoluysian atrophy 2 | 21
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
tuberculosis and treatment for 3 months 2 | 179
ulcerative colitis 2 | 1,819
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Antiphospholipid syndrome 1 | 19
Constipation 1 | 181
Death in early childhood 1 | 82
Death in infancy 1 | 82
Dyschezia 1 | 135
Gaucher disease type 1 1 | 180
Kidney Diseases 1 | 114
Malabsorption 1 | 82
Necrosis 1 | 53
Neoplasm Metastasis 1 | 168
Osteoporosis 1 | 363
Weight decreased 1 | 103
facioscapulohumeral dystrophy 1 | 288

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

GO Function

cadherin binding involved in c... 18 | 18
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-3 PKP3 Tbio Non-IDG -1.37372 26.0 200
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 BAIAP2L1 Tbio Non-IDG -1.09082 14.4 138
Cdc42 effector protein 1 CDC42EP1 Tbio Non-IDG -0.84557 7.77 106
Ras-related protein Rab-10 RAB10 Tbio Enzyme -1.62208 41.1 164
Tripartite motif-containing protein 29 TRIM29 Tbio Non-IDG -1.42599 31.3 334
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.17010 139.0 378
Tropomodulin-3 TMOD3 Tbio Non-IDG -1.07490 13.0 95