Development Level

Tbio 30 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal tail morphology 1 | 25
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating creatine... 1 | 4
decreased circulating serum al... 1 | 82
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating creatine... 1 | 5
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
small heart 1 | 10

Disease

Carcinoma 20 | 11,493
ovarian cancer 20 | 8,520
medulloblastoma, large-cell 18 | 6,241
lung cancer 15 | 4,740
glioblastoma 14 | 5,792
osteosarcoma 14 | 7,950
atypical teratoid / rhabdoid tumor 12 | 5,112
psoriasis 12 | 6,694
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
oligodendroglioma 10 | 2,850
Breast cancer 9 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
primitive neuroectodermal tumor 9 | 3,035
Neurodegenerative disease 8 | 414
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
colon cancer 7 | 1,478
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
Cognitive delay 6 | 608
Depressive disorder 6 | 409
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Mental and motor retardation 6 | 608
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
diabetes mellitus 6 | 1,728
Autosomal recessive predisposition 5 | 1,442
Parkinson's disease 5 | 392
Short stature 5 | 531
Waldenstrons macroglobulinemia 5 | 765
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
urothelial carcinoma 5 | 318
Alzheimer's disease 4 | 658
Dull intelligence 4 | 645
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Muscle hypotonia 4 | 571
Obesity 4 | 678
Poor school performance 4 | 645
Strabismus 4 | 270
chronic rhinosinusitis 4 | 512
dermatomyositis 4 | 966
pancreatic cancer 4 | 2,398
pediatric high grade glioma 4 | 1,064
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Anteverted nostril 3 | 191
Anxiety 3 | 136
Autistic Disorder 3 | 364
Big calvaria 3 | 147
Blepharoptosis 3 | 231
Broad flat nasal bridge 3 | 236
Cerebellar Ataxia 3 | 304
Cryptorchidism 3 | 296
Dementia 3 | 175
Failure to gain weight 3 | 365
Hirsutism 3 | 47
Huntington's disease 3 | 76
Hyperreflexia 3 | 209
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hypoplastic feet 3 | 66
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Infantile onset 3 | 238
Malaria 3 | 160
Mental Depression 3 | 333
Mood Disorders 3 | 184
Multicystic Dysplastic Kidney 3 | 52
Muscle Spasticity 3 | 195
Muscular atrophy 3 | 71
Nasal bridge wide 3 | 236
Neurodevelopmental Disorders 3 | 70
Nystagmus 3 | 317
Pediatric failure to thrive 3 | 365
Seizures 3 | 596
Short nose 3 | 132
Small nose 3 | 132
cutaneous lupus erythematosus 3 | 1,057
gastric cancer 3 | 459
interstitial cystitis 3 | 2,312
nasopharyngeal carcinoma 3 | 1,058
obsessive-compulsive disorder 3 | 61

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Respiratory system 36 | 16,393
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192
Nervous System 35 | 16,725

Target Family

Non-IDG 26 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

GO Function

beta-tubulin binding 36 | 36
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Microtubule-associated protein 1S MAP1S Tbio Non-IDG -1.49769 36.1 141
Emerin EMD Tbio Non-IDG -2.80459 640.6 299
Structural maintenance of chromosomes protein 3 SMC3 Tbio Non-IDG -2.10209 115.2 244