Development Level

Tbio 5 | 11,445
Tclin 1 | 613

IMPC Phenotype

decreased bone mineral content 2 | 151
decreased total body fat amoun... 2 | 207
increased circulating phosphat... 2 | 26
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal esophagus morphology 1 | 5
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged gallbladder 1 | 2
enlarged kidney 1 | 14
enlarged spleen 1 | 41
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

osteosarcoma 5 | 7,950
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Bipolar Disorder 3 | 666
Cancer 3 | 2,499
Carcinoma 3 | 11,493
Depressive disorder 3 | 409
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Mood Disorders 3 | 184
Schizophrenia 3 | 1,160
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
non-small cell lung cancer 3 | 2,890
psoriasis 3 | 6,694
Alcohol dependence 2 | 107
Alcoholic Intoxication, Chronic 2 | 289
Cocaine Dependence 2 | 51
Epilepsy 2 | 792
Unipolar Depression 2 | 250
astrocytic glioma 2 | 2,597
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Alzheimer's disease 1 | 658
Amnestic disorder 1 | 35
Amphetamine-Related Disorders 1 | 74
Arts syndrome 1 | 26
Atopic dermatitis 1 | 952
BARDET-BIEDL SYNDROME 19 1 | 2
Biliary dyskinesia 1 | 7
Bone disease 1 | 10
Bradycardia 1 | 36
Brain Injuries 1 | 65
Breast cancer 1 | 3,578
Cataract 7 1 | 32
Cerebrovascular disease 1 | 238
Cocaine-Related Disorders 1 | 92
Constipation 1 | 181
Dementia 1 | 175
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Diabetic Neuropathies 1 | 14
Dysuria 1 | 26
Excessive salivation 1 | 5
Gastric ulcer 1 | 33
Gastrointestinal Radiography Adjunct 1 | 11
Gaucher disease type 3 1 | 67
General anesthesia 1 | 53
Huntington's disease 1 | 76
Hyperglycemia 1 | 137
Increased Urinary Frequency 1 | 11
Kidney cancer 1 | 2,613
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Experimental 1 | 769
Morphine dependence 1 | 16
Muscarine Toxicity 1 | 3
Myocardial Infarction 1 | 151
Neurogenic Urinary Bladder 1 | 6
Opiate dependence 1 | 29
Pain agnosia 1 | 104
Parkinson's disease 1 | 392
Peptic Ulcer 1 | 27
Perioperative Mydriasis 1 | 3
Pick disease 1 | 1,894
Pilocytic astrocytoma 1 | 56
Rubinstein-Taybi syndrome 1 | 10
Schistosomiasis 1 | 35
Sinus bradycardia 1 | 7
Social Anhedonia 1 | 2
Somatic mutation 1 | 61
Substance Withdrawal Syndrome 1 | 55
Substance abuse 1 | 59
Substance-Related Disorders 1 | 115
Toxic encephalopathy 1 | 141
Urge incontinence of urine 1 | 3
Urgent desire to urinate 1 | 11
Urinary Incontinence 1 | 50
Urinary Tract Irritation 1 | 24
Vagal Reflex Bradycardia 1 | 5
Vascular disease 1 | 319
WHIM syndrome 1 | 7
adrenocortical carcinoma 1 | 1,428
clear cell sarcoma 1 | 6
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
medulloblastoma 1 | 720
oligodendroglioma 1 | 2,850
sarcoidosis 1 | 370
spina bifida 1 | 1,074

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145
GPCR 1 | 408
Transcription Factor 1 | 1,400

GO Function

arrestin family protein bindin... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-arrestin-1 ARRB1 Tbio Non-IDG -2.63877 418.5 490
Muscarinic acetylcholine receptor M2 CHRM2 Tclin GPCR -2.70017 498.2 391
Cyclic AMP-responsive element-binding protein 1 CREB1 Tbio Transcription Factor -3.62610 3982.3 1574
Beta-arrestin-2 ARRB2 Tbio Non-IDG -2.72576 487.8 250
E3 ubiquitin-protein ligase Itchy homolog ITCH Tbio Enzyme -2.06799 109.7 232
Arrestin domain-containing protein 1 ARRDC1 Tbio Non-IDG -0.64334 4.40 108