Development Level

Tbio 7 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal coat- hair morphology 1 | 19
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
embryonic lethality prior to o... 1 | 239
increased aggression 1 | 4
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
Breast cancer 5 | 3,578
medulloblastoma, large-cell 5 | 6,241
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Rothmund-Thomson syndrome 3 | 19
Squamous cell carcinoma 3 | 129
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
Baller-Gerold syndrome 2 | 12
Bloom syndrome 2 | 29
Breast Neoplasms 2 | 445
Cancer 2 | 2,499
Cryptorchidism 2 | 296
Decreased size of teeth 2 | 62
Decreased width of tooth 2 | 59
Diarrhea 2 | 253
High pitched voice 2 | 23
Hypertensive disease 2 | 292
Intellectual disability 2 | 1,016
Kidney Diseases 2 | 114
Kidney cancer 2 | 2,613
Lymphoma 2 | 81
Malignant Squamous Cell Neoplasm 2 | 17
Mammary Neoplasms 2 | 425
Microdontia (disorder) 2 | 59
Myopia 2 | 176
Photosensitivity of skin 2 | 51
Rapadilino syndrome 2 | 7
Schimke immuno-osseous dysplasia 2 | 8
Short nose 2 | 132
Short stature 2 | 531
Small nose 2 | 132
Waldenstrons macroglobulinemia 2 | 765
Werner syndrome 2 | 29
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Absent carpal bones 1 | 2
Absent eyebrow 1 | 13
Absent finger 1 | 4
Absent metacarpal(s) 1 | 1
Annular pancreas 1 | 12
Anteriorly placed anus 1 | 7
Atrophic condition of skin 1 | 25
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 13
Brachyturricephaly 1 | 4
Brittle hair 1 | 25
Carpal bone anomalies 1 | 5
Cleft uvula 1 | 27
Congenital anomaly of spine 1 | 16
Congenital anomaly of the kidney 1 | 12
Congenital hypoplasia of radius 1 | 23
Forearm reduction defects 1 | 2
Hypoplasia of thumb 1 | 26
Juvenile zonular cataracts 1 | 1
Limited elbow movement 1 | 6
Limited shoulder movement 1 | 3
Madarosis of eyebrow 1 | 13
Midface capillary hemangioma 1 | 1
Mottled pigmentation 1 | 4
Nail Diseases 1 | 24
Nail abnormality 1 | 22
Patellar hypoplasia 1 | 2
Perineal fistula 1 | 1
Poikiloderma 1 | 14
Premature canities 1 | 24
Radial ray hypoplasia 1 | 23
Rectovaginal Fistula 1 | 5
Reduced tensile strength of hair 1 | 25
Rib fusion 1 | 16
Saddle nose 1 | 6
Thin hypoplastic alae nasi 1 | 51
Tooth hypoplasia 1 | 7
Tooth, Supernumerary 1 | 7

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 3 | 4,145

GO Function

annealing helicase activity 8 | 8
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA annealing helicase and endonuclease ZRANB3 ZRANB3 Tbio Enzyme -2.18014 154.3 36
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
ATP-dependent DNA helicase Q1 RECQL Tbio Enzyme -1.87053 80.0 73
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 SMARCAL1 Tbio Non-IDG -1.74852 65.1 133
DNA repair and recombination protein RAD54-like RAD54L Tbio Non-IDG -1.28409 19.0 161
Annexin A1 ANXA1 Tbio Non-IDG -2.90864 897.0 765
Bloom syndrome protein BLM Tchem Non-IDG -2.03028 104.1 314