Development Level

Tbio 29 | 11,445
Tchem 14 | 1,598

IMPC Phenotype

abnormal behavior 4 | 298
preweaning lethality, complete... 3 | 979
decreased circulating glucose ... 2 | 126
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal head morphology 1 | 10
abnormal social-conspecific in... 1 | 3
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating creatine... 1 | 5
increased circulating glycerol... 1 | 9
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19

Disease

Carcinoma 33 | 11,493
ovarian cancer 33 | 8,520
glioblastoma 25 | 5,792
osteosarcoma 25 | 7,950
Cancer 23 | 2,499
medulloblastoma, large-cell 23 | 6,241
atypical teratoid / rhabdoid tumor 21 | 5,112
psoriasis 20 | 6,694
lung cancer 18 | 4,740
Breast cancer 16 | 3,578
ependymoma 13 | 4,679
astrocytic glioma 12 | 2,597
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
oligodendroglioma 12 | 2,850
adult high grade glioma 11 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Kidney cancer 10 | 2,613
primitive neuroectodermal tumor 10 | 3,035
Breast Neoplasms 9 | 445
Intellectual disability 9 | 1,016
Mammary Neoplasms 9 | 425
Rheumatoid arthritis 9 | 1,191
Waldenstrons macroglobulinemia 9 | 765
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
group 4 medulloblastoma 8 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
juvenile dermatomyositis 8 | 1,187
lung adenocarcinoma 8 | 2,716
Astrocytoma, Pilocytic 7 | 3,081
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Multiple myeloma 7 | 1,332
Poor school performance 7 | 645
Schizophrenia 7 | 1,160
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
group 3 medulloblastoma 7 | 4,104
invasive ductal carcinoma 7 | 2,951
Crohn's disease 6 | 321
Obesity 6 | 678
Pick disease 6 | 1,894
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
lung carcinoma 6 | 2,843
medulloblastoma 6 | 720
pancreatic cancer 6 | 2,398
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Autistic Disorder 5 | 364
Broad flat nasal bridge 5 | 236
Liver cancer 5 | 604
Nasal bridge wide 5 | 236
Pancreatic Neoplasm 5 | 85
Pancreatic Neoplasms 5 | 85
Prostate cancer 5 | 175
Prostatic Neoplasms 5 | 495
Small head 5 | 374
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
pediatric high grade glioma 5 | 1,064
Adenoid Cystic Carcinoma 4 | 99
Carcinoma, Adenoid Cystic 4 | 99
Carcinoma, Hepatocellular 4 | 228
Colorectal Neoplasms 4 | 243
Immune system cancer 4 | 140
Liver carcinoma 4 | 240
Lymphoid leukemia 4 | 160
Mammary Neoplasms, Experimental 4 | 154
Muscle hypotonia 4 | 571
Myocardial Infarction 4 | 151
Nausea and vomiting 4 | 97
Neoplasm Invasiveness 4 | 161
Ovarian Neoplasms 4 | 102
aldosterone-producing adenoma 4 | 665
ductal carcinoma in situ 4 | 1,745
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
ovarian neoplasm 4 | 99
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Bipolar Disorder 3 | 666
Diabetes Mellitus, Type 2 3 | 142
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Major Depressive Disorder 3 | 301
Strabismus 3 | 270
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
interstitial cystitis 3 | 2,312
progressive supranuclear palsy 3 | 676
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis 3 | 2,010

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Skin and soft tissues 42 | 17,230
Blood and immune system 41 | 16,909
Cardiovascular System 41 | 15,192
Female tissues 41 | 17,400
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Urinary Tract 41 | 16,678

Target Family

Non-IDG 15 | 12,091
Epigenetic 10 | 242
Enzyme 7 | 4,145
Transcription Factor 7 | 1,400
Kinase 3 | 634
TF/Epigenetic 1 | 38

GO Function

androgen receptor binding 43 | 43
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
Calreticulin CALR Tbio Non-IDG -3.19563 1544.2 778
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Protein/nucleic acid deglycase DJ-1 PARK7 Tbio Enzyme -2.89261 835.5 625
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PPARGC1A Tbio Non-IDG -2.86449 728.1 274
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.86389 713.1 332
Lysine-specific histone demethylase 1A KDM1A Tchem Epigenetic -2.68692 516.3 473
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417