Development Level

Tbio 23 | 11,445
Tchem 13 | 1,598
Tdark 5 | 6,588

IMPC Phenotype

decreased caudal vertebrae num... 2 | 53
increased circulating iron lev... 2 | 30
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
cystolithiasis 1 | 3
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
polycystic kidney 1 | 15
short tibia 1 | 97
small kidney 1 | 16

Disease

Carcinoma 32 | 11,493
atypical teratoid / rhabdoid tumor 18 | 5,112
medulloblastoma, large-cell 18 | 6,241
ovarian cancer 18 | 8,520
osteosarcoma 17 | 7,950
ependymoma 16 | 4,679
psoriasis 15 | 6,694
glioblastoma 13 | 5,792
group 3 medulloblastoma 13 | 4,104
lung carcinoma 13 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung cancer 11 | 4,740
malignant mesothelioma 11 | 3,232
oligodendroglioma 11 | 2,850
Astrocytoma, Pilocytic 10 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pancreatic cancer 10 | 2,398
primitive neuroectodermal tumor 10 | 3,035
Schizophrenia 9 | 1,160
adult high grade glioma 9 | 3,801
subependymal giant cell astrocytoma 9 | 2,287
Breast cancer 8 | 3,578
invasive ductal carcinoma 8 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pituitary cancer 8 | 1,972
Epilepsy 7 | 792
Lysinuric protein intolerance 7 | 15
Pick disease 7 | 1,894
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
non-small cell lung cancer 7 | 2,890
Hartnup disease 6 | 13
interstitial cystitis 6 | 2,312
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Amyotrophic lateral sclerosis 5 | 451
Atopic dermatitis 5 | 952
Bipolar Disorder 5 | 666
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
atypical teratoid/rhabdoid tumor 5 | 357
ductal carcinoma in situ 5 | 1,745
pediatric high grade glioma 5 | 1,064
Cancer 4 | 2,499
Cystinuria 4 | 18
Dicarboxylic aminoaciduria 4 | 4
Iminoglycinuria 4 | 4
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
group 4 medulloblastoma 4 | 1,855
Allan-Herndon-Dudley syndrome 3 | 11
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
HYPERGLYCINURIA (disorder) 3 | 12
Hyperglycinuria 3 | 3
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Toxic encephalopathy 3 | 141
acute quadriplegic myopathy 3 | 1,158
gastric carcinoma 3 | 807
lung adenocarcinoma 3 | 2,716
primary pancreatic ductal adenocarcinoma 3 | 1,109
Alzheimer's disease 2 | 658
Autistic Disorder 2 | 364
Autosomal recessive predisposition 2 | 1,442
Depressive disorder 2 | 409
Down syndrome 2 | 499
Dull intelligence 2 | 645
Glaucoma 2 | 239
Liver Cirrhosis, Experimental 2 | 769
Major Depressive Disorder 2 | 301
Mental Depression 2 | 333
Nerve Degeneration 2 | 121
Parkinson's disease 2 | 392
Pellagra 2 | 26
Polycystic ovary syndrome 2 | 360
Unipolar Depression 2 | 250
Vascular disease 2 | 319
X-linked cerebral adrenoleukodystrophy 2 | 116
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
facioscapulohumeral dystrophy 2 | 288
fibroadenoma 2 | 559
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
non diabetic and post-ischemic heart failure 2 | 200
posterior fossa group B ependymoma 2 | 416
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Endocrine System 40 | 18,159
Male tissues 40 | 17,142
Nervous System 40 | 16,725
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Urinary Tract 39 | 16,678
Liver and Pancreas 38 | 16,750
Skin and soft tissues 38 | 17,230
Female tissues 37 | 17,400
Respiratory system 36 | 16,393
Cardiovascular System 32 | 15,192

Target Family

Transporter 41 | 473

GO Function

amino acid transmembrane trans... 41 | 41
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cationic amino acid transporter 3 SLC7A3 Tbio Transporter -2.20835 146.6 38
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.90516 156.1 254
Proton-coupled amino acid transporter 2 SLC36A2 Tchem Transporter -1.78507 61.5 88
Sodium-coupled neutral amino acid transporter 5 SLC38A5 Tbio Transporter -3.03889 1061.8 77
Sodium-coupled neutral amino acid transporter 3 SLC38A3 Tbio Transporter 0.00000 59
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
Cationic amino acid transporter 2 SLC7A2 Tbio Transporter -1.55868 37.6 57
Sodium-coupled neutral amino acid transporter 2 SLC38A2 Tbio Transporter -1.98482 96.5 91
Excitatory amino acid transporter 4 SLC1A6 Tchem Transporter -1.89314 75.8 107
Sodium-dependent neutral amino acid transporter B(0)AT1 SLC6A19 Tchem Transporter -1.89653 74.4 32