Development Level

Tclin 3 | 613

Disease

Acute exacerbation of asthma 3 | 14
Administration of Local Anesthetic Nerve Block 3 | 14
Allergic Reactions 3 | 7
Allergic conjunctivitis 3 | 22
Allergic rhinitis 3 | 94
Asthma 3 | 385
Asthma management 3 | 19
Benign prostatic hyperplasia 3 | 7
Bronchiectasis 3 | 64
Bronchitis 3 | 43
Carcinoma 3 | 11,493
Cerebral Ischemia 3 | 37
Common cold 3 | 67
Cough 3 | 23
Dermal Necrosis 3 | 6
Diagnostic Test for Pheochromocytoma 3 | 6
Dilated pupil 3 | 6
Dyspnea 3 | 76
Exacerbation of asthma 3 | 11
Fever 3 | 138
Headache disorder 3 | 19
Hemorrhoids 3 | 13
Hypertension Secondary to Pheochromocytoma 3 | 6
Hypertensive Emergencies 3 | 10
Hypertensive disorder 3 | 56
Hypertensive emergency 3 | 3
Influenza-like symptoms 3 | 16
Local anesthesia, by infiltration 3 | 14
Low blood pressure 3 | 9
Nasal congestion 3 | 21
Nasal discharge 3 | 24
Open-angle glaucoma 3 | 27
Orthostatic hypotension 3 | 9
Parkinson's disease 3 | 392
Paroxysmal hypertension 3 | 6
Paroxysmal supraventricular tachycardia 3 | 12
Peripheral vascular disease 3 | 87
Pheochromocytoma 3 | 24
Prevention of Hypertension in Pheochromocytoma 3 | 6
Prevention of Posterior Synechiae 3 | 4
Proctitis 3 | 13
Pruritus ani 3 | 14
Pulmonary emphysema 3 | 48
Rectal pain 3 | 3
Red eye 3 | 7
Rhinitis 3 | 54
Seasonal allergic rhinitis 3 | 9
Sinus headache 3 | 16
Sneezing 3 | 12
Vasomotor rhinitis 3 | 12
Wheezing 3 | 7
anaphylaxis 3 | 11
Essential Hypertension 2 | 94
Hyperekplexia 2 | 16
Reverse Mydriasis from Ophthalmic Adrenergic or Anticholinergic Agent 2 | 2
Schizophrenia 2 | 1,160
Ureter carcinoma 2 | 2
Ureterolithiasis 2 | 4
psoriasis 2 | 6,694
Attention deficit hyperactivity disorder 1 | 278
Bipolar Disorder 1 | 666
Cannabis dependence 1 | 23
Cardiomegaly 1 | 116
Cerebrovascular disease 1 | 238
Cocaine Dependence 1 | 51
Cocaine abuse 1 | 19
Diabetes Mellitus, Experimental 1 | 108
Disorder of blood vessel 1 | 4
Hypotension 1 | 82
Hypotension Secondary to Spinal Anesthesia 1 | 2
Kidney Diseases 1 | 114
Liver Cirrhosis 1 | 181
Liver Cirrhosis, Experimental 1 | 769
Local anesthesia 1 | 40
Major Depressive Disorder 1 | 301
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Myasthenia gravis 1 | 23
Nerve Degeneration 1 | 121
Neurotoxicity Syndromes 1 | 26
Persistent erythema of skin 1 | 2
Persistent pulmonary hypertension of the newborn 1 | 8
Prevention of Hypotension During Spinal Anesthesia 1 | 2
Seizures 1 | 596
Unipolar Depression 1 | 250
Ventricular Remodeling 1 | 5
cocaine use 1 | 11
lung cancer 1 | 4,740
medulloblastoma, large-cell 1 | 6,241

Tissue

Blood and immune system 3 | 16,909
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678
Cardiovascular System 2 | 15,192

Target Family

GPCR 3 | 408

GO Function

alpha1-adrenergic receptor act... 3 | 3
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
Alpha-1B adrenergic receptor ADRA1B Tclin GPCR -2.30594 201.5 364
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236