Development Level

Tbio 24 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
embryonic lethality prior to t... 2 | 278
increased body length 2 | 32
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal ileum morphology 1 | 2
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tail morphology 1 | 25
abnormal vocalization 1 | 21
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatine... 1 | 4
decreased fluid intake 1 | 3
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating creatine... 1 | 5
increased circulating sodium l... 1 | 71
increased total body fat amoun... 1 | 134
mydriasis 1 | 6
polycystic kidney 1 | 15
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10

Disease

Carcinoma 16 | 11,493
ovarian cancer 15 | 8,520
psoriasis 15 | 6,694
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 13 | 7,950
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
oligodendroglioma 11 | 2,850
Pick disease 10 | 1,894
astrocytic glioma 10 | 2,597
atypical teratoid / rhabdoid tumor 10 | 5,112
lung adenocarcinoma 10 | 2,716
Breast cancer 9 | 3,578
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
malignant mesothelioma 8 | 3,232
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
colon cancer 7 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
lung carcinoma 7 | 2,843
Depressive disorder 5 | 409
Intellectual disability 5 | 1,016
Obesity 5 | 678
Paraplegia 5 | 74
breast carcinoma 5 | 1,638
chronic rhinosinusitis 5 | 512
cutaneous lupus erythematosus 5 | 1,057
group 4 medulloblastoma 5 | 1,855
pituitary cancer 5 | 1,972
tuberculosis 5 | 2,010
Big calvaria 4 | 147
Dull intelligence 4 | 645
Endometriosis 4 | 540
Increased head circumference 4 | 147
Increased size of cranium 4 | 147
Increased size of skull 4 | 147
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Neurodegenerative disease 4 | 414
Poor school performance 4 | 645
Ritscher-Schinzel syndrome 4 | 11
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
pediatric high grade glioma 4 | 1,064
urothelial carcinoma 4 | 318
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Cognitive delay 3 | 608
Down syndrome 3 | 499
Frontal bossing 3 | 157
Global developmental delay 3 | 608
Hydrocephalus 3 | 152
Hypertensive disease 3 | 292
Kidney cancer 3 | 2,613
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Nystagmus 3 | 317
Parkinson's disease 3 | 392
Schizophrenia 3 | 1,160
Short stature 3 | 531
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
cystic fibrosis 3 | 1,696
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Anteverted nostril 2 | 191
Bipolar Disorder 2 | 666
Byzanthine arch palate 2 | 194
Creatine phosphokinase serum increased 2 | 110
Dementia 2 | 175
Elevated creatine kinase 2 | 110
Epilepsy 2 | 792
Huntington's disease 2 | 76
Hypertension 2 | 396
Mental Depression 2 | 333
Myopathy 2 | 185
Neurodevelopmental Disorders 2 | 70
Seizures 2 | 596
Short nose 2 | 132
Small nose 2 | 132
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Female tissues 29 | 17,400
Liver and Pancreas 29 | 16,750
Male tissues 29 | 17,142
Respiratory system 29 | 16,393
Skin and soft tissues 29 | 17,230
Urinary Tract 29 | 16,678
Cardiovascular System 28 | 15,192
Nervous System 27 | 16,725

Target Family

Non-IDG 20 | 12,091
Enzyme 9 | 4,145
Epigenetic 2 | 242
Ion Channel 1 | 344
Transporter 1 | 473

GO Function

alpha-tubulin binding 33 | 33
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Histone-lysine N-methyltransferase SETD2 SETD2 Tchem Epigenetic -2.83266 645.3 214
Putative WAS protein family homolog 4 WASH4P Tdark Non-IDG 0.00000 0
Protein BEX4 BEX4 Tbio Non-IDG -0.42070 1.71 90
WAS protein family homolog 2 WASH2P Tdark Non-IDG -0.28297 2.17 0
Neurocalcin-delta NCALD Tbio Non-IDG -1.30940 20.7 102
Sodium-dependent noradrenaline transporter SLC6A2 Tclin Transporter -2.87529 687.5 105