Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal startle reflex 1 | 15
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
embryonic lethality prior to o... 1 | 239
increased bone mineral density 1 | 72
increased hemoglobin content 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 9 | 11,493
ovarian cancer 8 | 8,520
osteosarcoma 7 | 7,950
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
psoriasis 6 | 6,694
interstitial cystitis 5 | 2,312
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Cancer 4 | 2,499
Cardiomyopathy 4 | 116
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Breast cancer 3 | 3,578
Dilated cardiomyopathy 3 | 56
Osteoporosis 3 | 363
Prostatic Neoplasms 3 | 495
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
group 3 medulloblastoma 3 | 4,104
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
Alopecia 2 | 115
Arrhythmogenic right ventricular cardiomyopathy 2 | 30
Astrocytoma, Pilocytic 2 | 3,081
Breast Neoplasms 2 | 445
Cardiomyopathy, Dilated 2 | 83
Cardiomyopathy, right ventricular 2 | 7
Disease Progression 2 | 136
Kidney cancer 2 | 2,613
Liver disease 2 | 237
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Nerve Degeneration 2 | 121
No-Reflow Phenomenon 2 | 3
Pick disease 2 | 1,894
Stomach Neoplasms 2 | 300
Syncope 2 | 22
Ventricular arrhythmia 2 | 27
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
tuberculosis 2 | 2,010
Abnormality of the musculature 1 | 16
Acute coronary syndrome 1 | 39
Adrenal Gland Neoplasms 1 | 11
Adrenal cortical adenocarcinoma 1 | 4
Adrenal gland cancer 1 | 12
Afro-textured hair 1 | 13
Ameloblastoma 1 | 24
Aneurysm 1 | 7
Aneurysmal disease 1 | 6
Angiosarcoma 1 | 11
Arrhythmogenic Right Ventricular Dysplasia, Familial, 9 1 | 1
Arrhythmogenic right ventricular cardiomyopathy, type 9 1 | 1
Biliary tract cancer 1 | 19
Bone cancer 1 | 16
Curly hair (finding) 1 | 14
DOID:3858 1 | 6
DOID:8600 1 | 4
Fragile skin 1 | 18
Hemangiosarcoma 1 | 18
Hepatoblastoma 1 | 19
Hepatocellular Adenoma 1 | 10
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Hyperprolactinemia 1 | 27
Increased gastric cancer 1 | 21
Intestinal benign neoplasm 1 | 12
Kinky hair texture 1 | 13
LEFT VENTRICULAR NONCOMPACTION 10 1 | 40
Leiomyosarcoma of uterus 1 | 13
Malignant neoplasm of ovary 1 | 4
Micronodular cirrhosis 1 | 12
Nappy hair texture 1 | 13
Palpitations 1 | 18
Papilledema 1 | 11
Retinitis pigmentosa 4 1 | 38
Retroperitoneal cancer 1 | 4
Sparse eyebrow 1 | 42
Sparse scalp hair 1 | 42
Stomach cancer 1 | 30
Subacute progressive viral hepatitis 1 | 9
Tachycardia, Ventricular 1 | 22
Transitional cell carcinoma of bladder 1 | 17
Uterine adnexa cancer 1 | 4
Ventricular aneurysm 1 | 2
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 1 | 4,145

GO Function

alpha-catenin binding 11 | 11
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Plakophilin-3 PKP3 Tbio Non-IDG -1.37372 26.0 200
Cadherin-24 CDH24 Tbio Non-IDG 0.02 1.02 83
Receptor-type tyrosine-protein phosphatase T PTPRT Tbio Enzyme -1.35450 23.1 83
LIM domain-containing protein ajuba AJUBA Tbio Non-IDG -1.15520 13.9 65
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Armadillo repeat-containing protein 7 ARMC7 Tdark Non-IDG 0.00000 1.00 50
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Junction plakoglobin JUP Tbio Non-IDG -2.01808 101.8 719
Protein numb homolog NUMB Tbio Non-IDG -2.60072 402.1 564