Development Level

Tbio 9 | 11,651
Tclin 6 | 612
Tchem 1 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
brachydactyly 1 | 19
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
syndactyly 1 | 23

Disease

Carcinoma 16 | 11,493
Kidney cancer 9 | 2,613
ependymoma 9 | 4,679
osteosarcoma 8 | 7,950
psoriasis 8 | 6,694
medulloblastoma, large-cell 7 | 6,241
Breast cancer 6 | 3,578
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Melanoma 5 | 711
Mood Disorders 5 | 184
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Hypertension 4 | 396
Hypertensive disease 4 | 292
Liver cancer 4 | 604
Skin cancer 4 | 469
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
Asthma 3 | 385
Atherosclerosis 3 | 291
Cardiomyopathy 3 | 116
Cognitive delay 3 | 608
Endometrial cancer 3 | 311
Global developmental delay 3 | 608
Increase in blood pressure 3 | 119
Mental and motor retardation 3 | 608
Parkinson's disease 3 | 392
Type 2 diabetes mellitus 3 | 272
adrenocortical carcinoma 3 | 1,428
breast carcinoma 3 | 1,638
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
Adenoma 2 | 167
Advanced bone age 2 | 35
Angina Pectoris 2 | 32
Atopic dermatitis 2 | 952
Atrial Fibrillation 2 | 124
Cancer 2 | 2,499
Carcinoma, Hepatocellular 2 | 228
Cardiomyopathies 2 | 110
Cerebrovascular accident 2 | 63
Creatine phosphokinase serum increased 2 | 110
Depressive disorder 2 | 409
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Elevated creatine kinase 2 | 110
Heart disease 2 | 306
Heart failure 2 | 162
Hepatomegaly 2 | 285
High density lipoprotein decreased 2 | 10
Highly variable severity 2 | 157
Hyperinsulinism 2 | 133
Hypertensive disorder 2 | 57
Hyperuricemia 2 | 47
Immune system cancer 2 | 140
Insulin Resistance 2 | 72
Large intestine cancer 2 | 126
Liver carcinoma 2 | 240
Long QT syndrome 2 | 39
Multiple Sclerosis 2 | 540
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Myopathy 2 | 185
Osteoporosis 2 | 363
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
Pulmonary hypertension 2 | 86
Refractive error 2 | 50
Renal Insufficiency 2 | 90
Reperfusion Injury 2 | 86
Variable expressivity 2 | 157
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
limb-girdle muscular dystrophy 2 | 37
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pulmonary arterial hypertension 2 | 76
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Male tissues 17 | 17,142
Skin and soft tissues 17 | 17,230
Liver and Pancreas 16 | 16,750
Nervous System 16 | 16,725
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Respiratory system 15 | 16,393

Target Family

Non-IDG 7 | 12,091
Ion Channel 5 | 344
Enzyme 2 | 4,145
Nuclear Receptor 2 | 48
GPCR 1 | 408

GO Function

alpha-actinin binding 17 | 17
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leucine-rich repeat-containing protein 10 LRRC10 Tdark Non-IDG -0.93112 8.19 42
Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D Tclin Ion Channel -2.43448 273.2 215
Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C Tclin Ion Channel -2.75188 537.5 330
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Peroxisome proliferator-activated receptor gamma PPARG Tclin Nuclear Receptor -3.96393 9579.5 773
Potassium voltage-gated channel subfamily A member 5 KCNA5 Tclin Ion Channel -2.61528 428.3 209
Retinoic acid receptor alpha RARA Tclin Nuclear Receptor -2.97339 919.3 562
Small conductance calcium-activated potassium channel protein 2 KCNN2 Tchem Ion Channel -1.38831 20.5 78
Xin actin-binding repeat-containing protein 2 XIRP2 Tbio Non-IDG -0.94115 9.06 17
Synaptopodin-2 SYNPO2 Tbio Non-IDG -1.31714 27.9 42