Development Level

Tchem 2 | 1,598
Tclin 2 | 613
Tbio 1 | 11,445

IMPC Phenotype

abnormal spine curvature 1 | 9
decreased circulating serum al... 1 | 82
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122

Disease

adult high grade glioma 4 | 3,801
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Carcinoma 3 | 11,493
Heart failure 3 | 162
Parkinson's disease 3 | 392
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
Acute exacerbation of asthma 2 | 14
Alzheimer's disease 2 | 658
Asthma 2 | 385
Asthma management 2 | 19
Atopic dermatitis 2 | 952
Bronchiectasis 2 | 64
Bronchitis 2 | 43
Cardiomegaly 2 | 116
Cardiovascular Diseases 2 | 59
Cerebrovascular disease 2 | 238
Depressive disorder 2 | 409
Hypertension 2 | 396
Hypertensive disease 2 | 292
Hypertensive disorder 2 | 56
Low blood pressure 2 | 9
Mental Depression 2 | 333
Mood Disorders 2 | 184
Myocardial Infarction 2 | 151
Neurodegenerative disease 2 | 414
Ocular hypertension 2 | 42
Open-angle glaucoma 2 | 27
Orthostatic hypotension 2 | 9
Pulmonary emphysema 2 | 48
aldosterone-producing adenoma 2 | 665
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
Acute coronary syndrome 1 | 39
Administration of Local Anesthetic Nerve Block 1 | 14
Allergic Reactions 1 | 7
Atrioventricular block 1 | 35
Birth Weight 1 | 13
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiac arrest 1 | 36
Cerebellar Dysmetria 1 | 56
Cerebral Ischemia 1 | 37
Congenital Abnormalities 1 | 11
Congenital Abnormality 1 | 11
Conscious sedation 1 | 10
Decompensated cardiac failure 1 | 9
Decreased visual acuity, progressive 1 | 36
Dermal Necrosis 1 | 6
Diagnostic Test for Pheochromocytoma 1 | 6
Diaphragmatic Hernia 1 | 40
Embryo Loss 1 | 7
Endomyocardial Fibrosis 1 | 13
Essential tremor 1 | 28
Exacerbation of asthma 1 | 11
Fibrosis 1 | 44
Gallbladder Neoplasms 1 | 10
Gilles de la Tourette syndrome 1 | 47
Granular cell tumor 1 | 10
Hernia, Diaphragmatic 1 | 40
Histiocytosis 1 | 12
Hyperemia 1 | 13
Hypertensive Emergencies 1 | 10
Local anesthesia, by infiltration 1 | 14
Migraine Prevention 1 | 23
Myocardial Reperfusion Injury 1 | 37
Myokymia 1 | 6
Nasal congestion 1 | 21
Nasal discharge 1 | 24
PARKINSON DISEASE 19, JUVENILE-ONSET 1 | 10
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paroxysmal hypertension 1 | 6
Paroxysmal supraventricular tachycardia 1 | 12
Peripheral Nervous System Diseases 1 | 52
Peripheral Neuropathy 1 | 134
Pheochromocytoma 1 | 24
Prevention of Cerebral Thrombosis 1 | 29
Prevention of Hypertension in Pheochromocytoma 1 | 6
Red eye 1 | 7
Rosacea 1 | 25
Skin disease 1 | 66
Supraventricular tachycardia 1 | 3
Young onset Parkinson disease 1 | 10
anaphylaxis 1 | 11
gallbladder neoplasm 1 | 10

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

GPCR 2 | 408
Enzyme 1 | 4,145
Kinase 1 | 634
Non-IDG 1 | 12,091

GO Function

alpha-2A adrenergic receptor b... 5 | 5
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Amyloid-like protein 1 APLP1 Tbio Non-IDG -1.88769 62.6 162
Beta-1 adrenergic receptor ADRB1 Tclin GPCR -2.88263 725.8 196
Ubiquitin carboxyl-terminal hydrolase isozyme L1 UCHL1 Tchem Enzyme -3.16318 1414.2 1378
Alpha-2C adrenergic receptor ADRA2C Tclin GPCR -1.97108 93.5 343
Beta-adrenergic receptor kinase 1 GRK2 Tchem Kinase -2.61043 428.8 455