Development Level

Tbio 9 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased fasted circulating g... 1 | 65
persistence of hyaloid vascula... 1 | 33

Disease

lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
Carcinoma 5 | 11,493
glioblastoma 5 | 5,792
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Cancer 4 | 2,499
Endometrial Neoplasms 4 | 55
Endometriosis 4 | 540
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
psoriasis 4 | 6,694
Alcoholic Intoxication, Chronic 3 | 289
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Diabetic complication 3 | 3
Dysmenorrhea 3 | 21
Epilepsy 3 | 792
Liver Cirrhosis, Experimental 3 | 769
Pain 3 | 103
Polycystic ovary syndrome 3 | 360
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
oligodendroglioma 3 | 2,850
Cell Transformation, Neoplastic 2 | 97
Cognitive delay 2 | 608
Diabetic neuropathy 2 | 4
Disorders of Sex Development 2 | 5
Dull intelligence 2 | 645
Episodic ataxia 2 | 22
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Gout 2 | 106
Hepatitis B 2 | 108
Hepatomegaly 2 | 285
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Neoplasms, Hormone-Dependent 2 | 3
Neoplastic Cell Transformation 2 | 89
Obesity 2 | 678
Osteoarthritis 2 | 184
Pancreatic cystadenoma 2 | 4
Pediatric failure to thrive 2 | 365
Pick disease 2 | 1,894
Poor school performance 2 | 645
Respiratory Distress Syndrome, Adult 2 | 40
Seizures 2 | 596
Small head 2 | 374
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Delayed Puberty 1 | 97
Galactosemia 1 | 19
High-grade hypermetropia 1 | 24
Hyperglycemia 1 | 137
Increased bilirubin level (finding) 1 | 18
Intrahepatic cholestasis 1 | 20
Juvenile rheumatoid arthritis 1 | 111
Legg-Calve-Perthes disease 1 | 14
Low serum estradiol levels 1 | 22
Manic mood 1 | 6
Phenylketonuria 1 | 20
Primary hypogonadism 1 | 37
Primary physiologic amenorrhea 1 | 55
Sparse body hair 1 | 32
Sparse pubic hair 1 | 31

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Cardiovascular System 10 | 15,192

Target Family

Enzyme 12 | 4,145
Ion Channel 2 | 344
Non-IDG 1 | 12,091

GO Function

aldo-keto reductase (NADP) act... 15 | 15
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aflatoxin B1 aldehyde reductase member 2 AKR7A2 Tbio Enzyme -2.57327 369.6 197
Sepiapterin reductase SPR Tbio Enzyme -1.58814 36.9 174
Aflatoxin B1 aldehyde reductase member 4 AKR7L Tdark Enzyme -1.01509 16.2 0
Inositol oxygenase MIOX Tbio Enzyme -1.73181 60.0 146
Voltage-gated potassium channel subunit beta-1 KCNAB1 Tbio Ion Channel -1.73441 56.3 218
Aldose reductase AKR1B1 Tclin Enzyme -3.27314 1915.8 350
Cytochrome b5 CYB5A Tbio Non-IDG -3.24845 1711.7 270
Alcohol dehydrogenase [NADP(+)] AKR1A1 Tchem Enzyme -2.13997 131.7 381
3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 Tbio Enzyme -1.87479 75.7 171
Aldo-keto reductase family 1 member C4 AKR1C4 Tbio Enzyme -1.70148 51.4 221