Development Level

Tbio 4 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 2 | 298
decreased bone mineral density 2 | 126
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung cancer 4 | 2,890
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Cancer 3 | 2,499
adrenocortical carcinoma 3 | 1,428
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
Alcoholic Intoxication, Chronic 2 | 289
Autosomal recessive predisposition 2 | 1,442
Flushing 2 | 60
Schizophrenia 2 | 1,160
Succinic semialdehyde dehydrogenase deficiency 2 | 16
acute myeloid leukemia 2 | 783
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
ependymoma 2 | 4,679
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormal skeletal development 1 | 60
Abnormality of retinal pigmentation 1 | 111
Alcohol abuse 1 | 50
Alcohol dependence 1 | 107
Alcoholic Intoxication 1 | 34
Alcoholism 1 | 45
Atopic dermatitis 1 | 952
Autoimmune lymphoproliferative syndrome type 4 1 | 6
Brain infarction 1 | 22
Central nervous system demyelination 1 | 28
Cerebral palsy 1 | 40
Coloboma 1 | 51
Colorectal Neoplasms 1 | 243
Corneal Injuries 1 | 1
Corneal erosion 1 | 16
Coronary artery disease 1 | 268
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
Dry skin 1 | 75
Dysarthria 1 | 192
Dysplasia of tooth enamel 1 | 35
Epilepsy 1 | 792
Erythema 1 | 58
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Gaucher disease type 1 1 | 180
Generalized hyperpigmentation 1 | 22
Heart Injuries 1 | 3
Heroin dependence 1 | 30
Hyperkeratosis 1 | 50
Hyperkyphosis 1 | 111
Hypoplasia of the optic nerve 1 | 17
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Intracranial aneurysm 1 | 24
Kidney disease 1 | 430
Kyphosis deformity of spine 1 | 114
Little's Disease 1 | 14
Liver Cirrhosis, Experimental 1 | 769
Liver disease 1 | 237
Macular degeneration 1 | 65
Matthew-Wood syndrome 1 | 11
Microphthalmia 1 | 76
Muscle Spasticity 1 | 195
Myopia 1 | 176
Osteochondrodysplasias 1 | 72
Photodysphoria 1 | 121
Photophobia 1 | 121
Precancerous Conditions 1 | 80
Pyramidal sign 1 | 29
Quadriplegia 1 | 20
Retinal Diseases 1 | 55
Retinal pigment epithelial abnormality 1 | 111
Seizures 1 | 596
Sengers syndrome 1 | 18
Squamous cell carcinoma of esophagus 1 | 77
Stomach Neoplasms 1 | 300
Substance abuse 1 | 59
Thin dental enamel 1 | 35
Vascular Diseases 1 | 16
Wernicke-Korsakoff syndrome 1 | 10
X-linked cerebral adrenoleukodystrophy 1 | 116
Xerosis 1 | 75
active Crohn's disease 1 | 922
esophageal cancer 1 | 22
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
limb girdle muscular dystrophy 2B 1 | 40
pediatric high grade glioma 1 | 1,064
substance-related disorder 1 | 162

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Enzyme 6 | 4,145

GO Function

aldehyde dehydrogenase [NAD(P)... 6 | 6
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 Tchem Enzyme -2.12624 141.3 310
Aldehyde dehydrogenase family 1 member A3 ALDH1A3 Tbio Enzyme -1.98798 93.8 120
Aldehyde dehydrogenase family 3 member B1 ALDH3B1 Tbio Enzyme 0.00000 182
Aldehyde dehydrogenase family 3 member B2 ALDH3B2 Tbio Enzyme -0.92036 7.80 176