Development Level

Tbio 6 | 11,651
Tclin 4 | 612
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal locomotor activation 1 | 16
cataract 1 | 92
decreased body weight 1 | 161
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ependymoma 10 | 4,679
ovarian cancer 10 | 8,520
group 3 medulloblastoma 9 | 4,104
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
Astrocytoma, Pilocytic 7 | 3,081
Carcinoma 7 | 11,493
astrocytic glioma 7 | 2,597
medulloblastoma, large-cell 7 | 6,241
oligodendroglioma 7 | 2,850
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
primitive neuroectodermal tumor 6 | 3,035
Hypertension 5 | 396
Schizophrenia 5 | 1,160
colon cancer 5 | 1,478
lung cancer 5 | 4,740
Cancer 4 | 2,499
Heart disease 4 | 306
Kidney cancer 4 | 2,613
Ventricular arrhythmia 4 | 27
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
osteosarcoma 4 | 7,950
pituitary cancer 4 | 1,972
Acquired metabolic disease 3 | 336
Alzheimer's disease 3 | 658
Amyloidosis 3 | 67
Aspergillosis 3 | 26
Asthma 3 | 385
Cerebrovascular disease 3 | 238
Epilepsy 3 | 792
Idiopathic scoliosis 3 | 31
Long QT syndrome 1 3 | 20
Malignant hyperthermia 3 | 26
Multiple epiphyseal dysplasia 3 | 18
Otitis externa 3 | 10
Pertussis 3 | 20
Pick disease 3 | 1,894
Pseudoachondroplasia 3 | 14
Sporotrichosis 3 | 10
Supraventricular arrhythmia 3 | 4
Tetanus 3 | 68
Toxic encephalopathy 3 | 141
chronic rhinosinusitis 3 | 512
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Anxiety 2 | 136
Bipolar Disorder 2 | 666
Cardiomyopathies 2 | 110
Chronic obstructive pulmonary disease 2 | 184
Depressive disorder 2 | 409
Duchenne muscular dystrophy 2 | 601
Fibrosis 2 | 44
Mental Depression 2 | 333
Osteoporosis 2 | 363
Parkinson's disease 2 | 392
Ventricular Dysfunction, Left 2 | 22
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
Administration of Local Anesthetic Nerve Block 1 | 14
Atrioventricular block 1 | 35
Bronchiectasis 1 | 64
Canavan disease 1 | 10
Cardiac arrest 1 | 36
Common cold 1 | 69
Corneal ectasia 1 | 11
Decompensated cardiac failure 1 | 9
Essential tremor 1 | 28
Gaucher disease type 3 1 | 67
Hemangioma 1 | 69
Hyperlipidemia 1 | 43
Hypertensive disorder 1 | 57
Hypokalemia 1 | 52
Insulin Resistance 1 | 72
Local anesthesia, by infiltration 1 | 14
Memory Disorders 1 | 40
Migraine Prevention 1 | 23
Motor Skills Disorders 1 | 8
Myasthenia gravis 1 | 23
Nasal congestion 1 | 23
Open-angle glaucoma 1 | 27
Pulmonary emphysema 1 | 48
Rhinitis 1 | 55
Tear film insufficiency 1 | 15
Timothy syndrome 1 | 11

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Enzyme 7 | 4,145
Non-IDG 3 | 12,091
GPCR 2 | 408

GO Function

adenylate cyclase binding 12 | 12
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pituitary adenylate cyclase-activating polypeptide type I receptor ADCYAP1R1 Tchem GPCR -1.98111 94.8 184
Adenylyl cyclase-associated protein 1 CAP1 Tbio Enzyme -1.03272 8.93 160
Adenylyl cyclase-associated protein 2 CAP2 Tbio Enzyme -0.39794 2.39 125
A-kinase anchor protein 5 AKAP5 Tbio Enzyme -2.07031 126.3 196
Calmodulin-1 CALM3 Tclin Non-IDG -3.59093 5859.5 0
Adenylate cyclase type 2 ADCY2 Tbio Enzyme -1.37166 21.4 117
Calmodulin-2 CALM3 Tclin Non-IDG -3.59834 5859.5 0
Calmodulin-3 CALM3 Tclin Non-IDG -3.59140 5859.5 0
A-kinase anchor protein 12 AKAP12 Tbio Enzyme -2.00948 126.8 160
Adenylate cyclase type 5 ADCY5 Tchem Enzyme -2.37306 236.5 103