Development Level

Tchem 8 | 1,388
Tbio 2 | 11,651

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
improved glucose tolerance 1 | 79
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16

Disease

Obesity 7 | 678
osteosarcoma 7 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,954
Carcinoma 5 | 11,493
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,290
invasive ductal carcinoma 4 | 2,950
pancreatic cancer 4 | 2,398
Cannabis dependence 3 | 23
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,637
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
non-small cell lung cancer 3 | 2,890
ovarian cancer 3 | 8,519
primary pancreatic ductal adenocarcinoma 3 | 1,108
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,577
Pain agnosia 2 | 104
Rheumatoid arthritis 2 | 1,191
active ulcerative colitis 2 | 764
colon cancer 2 | 1,478
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Abdominal Pain 1 | 98
Action Tremor 1 | 22
Alcoholic Intoxication, Chronic 1 | 289
Atherosclerosis 1 | 291
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
Babinski Reflex 1 | 100
Barrett's esophagus 1 | 182
Barth syndrome 1 | 23
Cerebellar Dysmetria 1 | 56
Cerebellar degeneration 1 | 103
Congenital pes cavus 1 | 88
Decreased nerve conduction velocity 1 | 35
Decreased tendon reflex 1 | 122
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Distal amyotrophy 1 | 51
Distal sensory impairment 1 | 52
Dysarthria 1 | 192
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Huntington Disease 1 | 13
Hyperreflexia 1 | 209
Infratentorial atrophy 1 | 103
Major Depressive Disorder 1 | 301
Marijuana Abuse 1 | 31
Mood Disorders 1 | 184
Muscle Spasticity 1 | 195
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
Nonorganic psychosis 1 | 84
Osteoporosis 1 | 363
Pancreatitis 1 | 123
Pancreatitis, Chronic 1 | 9
Peripheral Neuropathy 1 | 134
Peripheral sensorimotor neuropathy 1 | 16
Phenotypic variability 1 | 150
Pick disease 1 | 1,894
Polycystic kidney disease 1 1 | 21
Polyneuropathy 1 | 64
Psychotic Disorders 1 | 151
Schizophrenia 1 | 1,160
Seizures 1 | 596
Sengers syndrome 1 | 18
Sensorineural Hearing Loss (disorder) 1 | 284
Slow progression 1 | 89
Spastic Quadriplegia 1 | 42
Steatorrhea 1 | 34
Substance Withdrawal Syndrome 1 | 55
Substance-Related Disorders 1 | 115
Unipolar Depression 1 | 250
active Crohn's disease 1 | 922
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
atypical teratoid/rhabdoid tumor 1 | 357
diabetes mellitus 1 | 1,728
esophageal adenocarcinoma 1 | 737
maturity-onset diabetes of the young 1 | 32
oligodendroglioma 1 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pterygium 1 | 76

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 10 | 4,145

GO Function

acylglycerol lipase activity 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Monoglyceride lipase MGLL Tchem Enzyme -2.48367 314.7 296
Monoacylglycerol lipase ABHD6 ABHD6 Tchem Enzyme -1.37418 26.1 71
Sn1-specific diacylglycerol lipase alpha DAGLA Tchem Enzyme -1.11500 11.4 129
Sn1-specific diacylglycerol lipase beta DAGLB Tchem Enzyme -1.26798 14.5 78
Protein ABHD16A ABHD16A Tchem Enzyme -1.69084 46.7 72
Fatty-acid amide hydrolase 1 FAAH Tchem Enzyme -2.62088 429.1 312
Monoacylglycerol lipase ABHD2 ABHD2 Tbio Enzyme -1.02814 11.4 112
Bile salt-activated lipase CEL Tchem Enzyme -2.57254 373.8 0
Pancreatic lipase-related protein 2 PNLIPRP2 Tbio Enzyme 0.00000 0
Monoacylglycerol lipase ABHD12 ABHD12 Tchem Enzyme -1.27115 18.3 143