Development Level

Tbio 5 | 11,445
Tchem 5 | 1,598

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal skin condition 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 9 | 11,493
ovarian cancer 6 | 8,520
Kidney cancer 5 | 2,613
Breast cancer 4 | 3,578
Cancer 4 | 2,499
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
psoriasis 4 | 6,694
Colonic Neoplasms 3 | 142
Hypertension 3 | 396
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Brain Ischemia 2 | 110
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
Cell Transformation, Neoplastic 2 | 97
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Dilated cardiomyopathy 2 | 56
Endometrial cancer 2 | 311
Familial isolated dilated cardiomyopathy 2 | 41
Heat Stroke 2 | 13
Hypertensive disease 2 | 292
Hypertrophic Cardiomyopathy 2 | 117
Kidney Failure, Chronic 2 | 46
Kidney disease 2 | 430
LEFT VENTRICULAR NONCOMPACTION 10 2 | 40
LEFT VENTRICULAR NONCOMPACTION 8 2 | 40
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Mantle cell lymphoma 2 | 23
Multiple myeloma 2 | 1,332
Neoplastic Cell Transformation 2 | 89
Pick disease 2 | 1,894
Unipolar Depression 2 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
esophageal adenocarcinoma 2 | 737
hereditary spastic paraplegia 2 | 318
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormality of the choroid 1 | 7
Autosomal dominant polycystic kidney disease 1 | 31
Biliary cirrhosis 1 | 45
Brain Neoplasms 1 | 33
Choroid Diseases 1 | 7
Chronic Kidney Diseases 1 | 13
Chronic Obstructive Airway Disease 1 | 37
Colitis, Ulcerative 1 | 59
Color vision defect, severe 1 | 31
Cone-rod dystrophy 2 1 | 2
Cone/cone-rod dystrophy 1 | 20
Cystitis 1 | 15
Disease Susceptibility 1 | 5
EMG: myopathic abnormalities 1 | 22
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Hepatitis 1 | 67
Limb ischemia 1 | 15
Liver Cirrhosis, Biliary 1 | 33
Myasthenia gravis 1 | 23
Neoplasms, Experimental 1 | 40
Neurodegenerative Diseases 1 | 38
Ovarian Cysts 1 | 41
Polycystic Kidney, Autosomal Dominant 1 | 7
Polycystic kidney disease, type 2 1 | 1
Polycystic liver disease 1 | 16
Primary cutaneous amyloidosis 1 | 29
Progressive renal failure 1 | 13
Recurrent sinopulmonary infections 1 | 6
Recurrent skin infections 1 | 21
Retinal flecking 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Skin Neoplasms 1 | 69
Stargardt disease 1 | 6
Tachycardia, Ventricular 1 | 22
Thymoma 1 | 16

Tissue

Liver and Pancreas 10 | 16,750
Nervous System 10 | 16,725
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Male tissues 9 | 17,142
Skin and soft tissues 9 | 17,230
Respiratory system 8 | 16,393

Target Family

Non-IDG 4 | 12,091
Ion Channel 3 | 344
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Function

actinin binding 10 | 10
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Prominin-1 PROM1 Tbio Non-IDG -3.30229 2035.0 351
Titin TTN Tbio Kinase -3.24415 1743.0 123
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -2.00418 105.2 236
MICAL-like protein 2 MICALL2 Tbio Non-IDG -0.91217 11.2 67
Short transient receptor potential channel 6 TRPC6 Tchem Ion Channel -2.82303 661.6 320
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.25002 172.0 220
Transcription factor p65 RELA Tchem Transcription Factor -3.00328 988.5 2215
PDZ and LIM domain protein 5 PDLIM5 Tbio Non-IDG -2.56478 370.4 237
Nuclear factor NF-kappa-B p105 subunit NFKB1 Tchem Transcription Factor -2.74349 505.0 1762