Development Level

Tbio 19 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal skin condition 1 | 6
absent teeth 1 | 3
corneal opacity 1 | 32
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
fused cornea and lens 1 | 5
hyperactivity 1 | 148
increased circulating amylase ... 1 | 25
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased monocyte cell number 1 | 63
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 17 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 10 | 8,520
group 3 medulloblastoma 9 | 4,104
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
psoriasis 9 | 6,694
glioblastoma 8 | 5,792
Cancer 7 | 2,499
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
adult high grade glioma 6 | 3,801
primitive neuroectodermal tumor 6 | 3,035
acute quadriplegic myopathy 5 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
astrocytic glioma 4 | 2,597
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Dilated cardiomyopathy 3 | 56
Hydrolethalus syndrome 3 | 128
Hypertrophic Cardiomyopathy 3 | 117
Liver Cirrhosis, Experimental 3 | 769
Multiple myeloma 3 | 1,332
Myocardial Infarction 3 | 151
Schizophrenia 3 | 1,160
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Adenocarcinoma 2 | 122
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Bipolar Disorder 2 | 666
Blastic phase chronic myeloid leukemia 2 | 58
Breast Neoplasms 2 | 445
Cardiomyopathy 2 | 116
Cardiomyopathy, Hypertrophic 2 | 24
Chronic Myelocytic Leukemia Accelerated Phase 2 | 59
Chronic eosinophilic leukemia 2 | 11
Chronic phase chronic myeloid leukemia 2 | 45
Depressive disorder 2 | 409
Dermatofibrosarcoma protuberans 2 | 15
Diabetes Mellitus, Experimental 2 | 108
Diabetic Nephropathies 2 | 37
Diabetic Nephropathy 2 | 34
Esophageal Neoplasms 2 | 69
Fatigue 2 | 182
Gastrointestinal stromal tumor 2 | 62
Idiopathic hypereosinophilic syndrome 2 | 10
Left ventricular noncompaction 2 | 26
Liver neoplasms 2 | 130
Mammary Neoplasms 2 | 425
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 2 | 9
Myocardial Ischemia 2 | 169
Nemaline myopathy 2 | 17
Obesity 2 | 678
Peripheral vascular disease 2 | 87
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 2 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 2 | 47
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
Recurrent respiratory infections 2 | 141
Stomach Neoplasms 2 | 300
Systemic mast cell disease 2 | 12
Tachycardia, Ventricular 2 | 22
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
limb girdle muscular dystrophy 2A 2 | 213
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
Hyperglycemia 1 | 137

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678
Nervous System 25 | 16,725
Respiratory system 25 | 16,393

Target Family

Non-IDG 22 | 12,091
Kinase 3 | 634
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Function

actin monomer binding 27 | 27
metal ion binding 2,256 | 2,256
DNA binding 1,481 | 1,481
ATP binding 1,477 | 1,477
RNA binding 1,383 | 1,383
identical protein binding 1,084 | 1,084
zinc ion binding 828 | 828
transcription factor activity,... 816 | 816
protein homodimerization activ... 801 | 801
calcium ion binding 690 | 690
G-protein coupled receptor act... 658 | 658
protein heterodimerization act... 473 | 473
olfactory receptor activity 425 | 425
protein kinase binding 410 | 410
chromatin binding 378 | 378
receptor binding 374 | 374
sequence-specific DNA binding 374 | 374
GTP binding 372 | 372
protein serine-threonine kinas... 360 | 360
RNA polymerase II core promote... 346 | 346
enzyme binding 340 | 340
ubiquitin protein ligase bindi... 301 | 301
transcription factor binding 297 | 297
GTPase activity 286 | 286
GTPase activator activity 281 | 281
cadherin binding 277 | 277
transcriptional activator acti... 274 | 274
actin binding 272 | 272
ubiquitin-protein transferase ... 260 | 260
transcription coactivator acti... 249 | 249
serine-type endopeptidase acti... 246 | 246
protein domain specific bindin... 241 | 241
protein complex binding 231 | 231
structural molecule activity 229 | 229
microtubule binding 212 | 212
nucleic acid binding 210 | 210
signal transducer activity 208 | 208
transcription regulatory regio... 205 | 205
RNA polymerase II regulatory r... 204 | 204
receptor activity 202 | 202
transmembrane signaling recept... 202 | 202
ubiquitin protein ligase activ... 202 | 202
transcription corepressor acti... 200 | 200
magnesium ion binding 197 | 197
calmodulin binding 194 | 194
protein C-terminus binding 191 | 191
protein kinase activity 182 | 182
carbohydrate binding 178 | 178
RNA polymerase II transcriptio... 174 | 174
cytokine activity 171 | 171
antigen binding 169 | 169
growth factor activity 162 | 162
heparin binding 161 | 161
protein dimerization activity 161 | 161
structural constituent of ribo... 161 | 161
actin filament binding 151 | 151
iron ion binding 139 | 139
transcriptional activator acti... 139 | 139
Rab GTPase binding 138 | 138
transcriptional repressor acti... 135 | 135
transporter activity 134 | 134
heme binding 129 | 129
ATPase activity 128 | 128
lipid binding 127 | 127
SH3 domain binding 125 | 125
protein tyrosine kinase activi... 122 | 122
ion channel binding 118 | 118
mRNA binding 118 | 118
Ras guanyl-nucleotide exchange... 116 | 116
metalloendopeptidase activity 115 | 115
unfolded protein binding 113 | 113
integrin binding 112 | 112
histone binding 111 | 111
protease binding 108 | 108
histone deacetylase binding 107 | 107
structural constituent of cyto... 107 | 107
guanyl-nucleotide exchange fac... 106 | 106
protein N-terminus binding 106 | 106
peptide antigen binding 103 | 103
hormone activity 96 | 96
serine-type endopeptidase inhi... 96 | 96
odorant binding 94 | 94
kinase binding 92 | 92
single-stranded DNA binding 92 | 92
chaperone binding 91 | 91
oxidoreductase activity 91 | 91
protein tyrosine phosphatase a... 91 | 91
PDZ domain binding 87 | 87
thiol-dependent ubiquitinyl hy... 86 | 86
kinase activity 84 | 84
transcriptional repressor acti... 84 | 84
beta-catenin binding 83 | 83
hydrolase activity 80 | 80
peptidase activity 80 | 80
protein binding, bridging 80 | 80
ATPase binding 79 | 79
double-stranded DNA binding 79 | 79
phospholipid binding 78 | 78
phosphatidylinositol binding 77 | 77
thiol-dependent ubiquitin-spec... 76 | 76
drug binding 75 | 75

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thymosin beta-15B TMSB15B Tdark Non-IDG -0.96314 17.3 9
Thymosin beta-15A TMSB15B Tdark Non-IDG -0.96314 17.3 40
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Leiomodin-3 LMOD3 Tbio Non-IDG -1.00928 10.3 27
Thymosin beta-10 TMSB10 Tbio Non-IDG -2.17282 149.8 81
Abelson tyrosine-protein kinase 2 ABL2 Tchem Kinase -1.86293 71.2 358
Metastasis suppressor protein 1 MTSS1 Tbio Non-IDG -2.73880 551.8 126
Leiomodin-2 LMOD2 Tbio Non-IDG -0.89671 9.37 55
Profilin-4 PFN4 Tdark Non-IDG -0.52386 3.41 23
Thymosin beta-4 TMSB4X Tbio Non-IDG -2.71532 511.8 173